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Senior Python Api Develop Jobs (NOW HIRING)

Sr Python Developer

Fort Mill, SC · Remote

$124K - $167K/yr

Design, develop, and maintain a central, monolithic system built on Python and Django. * Develop ... Experience designing and maintaining API platforms that serve multiple internal consumers.

Senior Python Developer

Princeton, NJ · Hybrid

$127K - $171K/yr

Develop, optimize, and maintain core Python applications and services, ensuring high code quality ... Authentication/authorization patterns (e.g., API keys, OAuth where applicable) * Reliable ...

Senior Python Developer

Chantilly, VA · On-site

$120K - $180K/yr

Design, develop, test, debug and document solutions with direction from senior team members from ... Experience with API design and implementation that conforms with REST standards * Experience with ...

Senior Python Developer

Jersey City, NJ · Hybrid

$126K - $170K/yr

Develop, optimize, and maintain core Python applications and services, ensuring high code quality ... Authentication/authorization patterns (e.g., API keys, OAuth where applicable) * Reliable ...

Senior Python Developer

Morristown, NJ · Hybrid

$125K - $168K/yr

Develop, optimize, and maintain core Python applications and services, ensuring high code quality ... Authentication/authorization patterns (e.g., API keys, OAuth where applicable) * Reliable ...

Python Developer

Newark, NJ · On-site

$52.50 - $72.50/hr

Should have hands on experience in Python API development. * Good oral and written communication skills. Responsibilities: * Ability to develop and maintain complex code written in Python. * Maintain ...

Senior Python Developer

San Jose, CA · On-site

$142K - $191K/yr

Senior Python DeveloperLooking for a passionate Python developer who is excited about joining a ... API services, experience of consuming services with Python technology stack will be highly ...

Senior Python Developer

San Jose, CA · On-site

$142K - $191K/yr

Senior Python Developer Looking for a passionate Python developer who is excited about joining a ... API services, experience of consuming services with Python technology stack will be highly ...

Sr. Python Developer

Richmond, VA · On-site

$118K - $160K/yr

They are in search of a highly motivated Sr. Python Developer who will be involved in design ... with SNS • API Experience • Applications side experience • Experience with data flows ...

Senior Python Developer

San Jose, CA · On-site

$142K - $191K/yr

Senior Python Developer Looking for a passionate Python developer who is excited about joining a ... Thorough understanding and knowledge of RESTful API services, experience of consuming services with ...

Python API Developer - SWE II

Annapolis Junction, MD · On-site

$51.25 - $70.75/hr

Responsibilities : • Design, develop, and sustain scalable, secure Python-based APIs • ... API Gateway, S3, EC2, IAM, and CloudWatch • Collaborate with cross-functional engineering, data ...

Senior Python Developer

Dallas, TX · On-site

$120K - $162K/yr

Design, develop, and maintain scalable Python-based applications in AWS cloud environments. Build ... Hands-on experience with AWS services including Lambda, S3, API Gateway, DynamoDB, and ...

Senior Python Developer

Manhattan, NY · On-site

$65K - $117K/yr

About the role As a Senior Python Developer, you will make an impact by designing and building ... API versioning, error handling, and documentation. * Develop event-driven and asynchronous ...

Senior Python Engineer

Chicago, IL · On-site

$125K - $168K/yr

Job Summary : 1872 Consulting is seeking a Senior Python Engineer to join their focused Software ... REST/SOAP API with third party applications • Design and develop new user interfaces for ...

Showing results 21-40

Senior Python Api Develop information

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$55K

$142K

$195K

How much do senior python api develop jobs pay per year?

As of Sep 10, 2026, the average yearly pay for senior python api develop in the United States is $141,976.00, according to ZipRecruiter salary data. Most workers in this role earn between $121,500.00 and $163,500.00 per year, depending on experience, location, and employer.

What are popular job titles related to Senior Python Api Develop jobs?

For Senior Python Api Develop jobs, the most frequently searched job titles are:

Infographic showing various Senior Python Api Develop job openings in the United States as of July 2026, with employment types broken down into 1% As Needed, 87% Full Time, 9% Part Time, and 3% Contract. Highlights an 90% Physical, 3% Hybrid, and 7% Remote job distribution, with an average salary of $141,976 per year, or $68.3 per hour.

Sr Python Developer

Fort Mill, SC • Remote

1 point system
IT Services • 51 - 200 employees

$124K - $167K/yr

Contractor

Re-posted 18 days ago


Job description

Hi ,
I hope you're doing well.

I'm reaching out regarding an exciting opportunity that I believe aligns well with your background and skill set.

To move forward, could you please provide the following details along with latest copy of resume:

two references are required in order to submit for this role. Without those I won’t be able to submit you.

Work Authorization and Expiry (If any)

LinkedIn Profile URL

Current Location with Zip code

Pay Expectation on W2 (hourly)

Complete JD:

Job Title

Sr Python Developer

Location

100% Remote Work

Duration

6 months + (Contract)

MUST HAVE:

  • 7+ years of experience, senior level
  • Experience in Design and Development
  • Full Stack with Python, Django, and Typescript
  • Typescript
  • Heavy APIs on backend
  • MySQL

Nice-to-Have / Preferred:

  • AI Tools – Claude, Codex, etc

Job Description:

Role Overview

We are seeking a Senior Software Engineer to support a core monolithic system that orchestrates lab order intake, processing, and interpretation. This role requires an individual who can take ambiguous, complex problems and drive them to completion. The successful candidate will act as a technical leader, mentoring other engineers and raising the bar for the team in architecture and execution, with a heavy focus on integration work connecting internal systems with lab pipelines.

Key Responsibilities

  • Own and deliver projects across product, platform, and stakeholder teams.
  • Design, develop, and maintain a central, monolithic system built on Python and Django.
  • Develop and enhance system integrations and core platform functionality with a strong emphasis on API-driven architecture.
  • Perform foundational engineering work focused on system improvements, stability, and modernization.
  • Provide production support, including participating in an on-call rotation and troubleshooting bugs.
  • Mentor teammates and elevate the team's technical execution standards.
  • Communicate clearly with both technical and non-technical audiences.

Required Qualifications

Experience: A minimum of 7+ years of professional software engineering experience is required. Candidates must demonstrate strong experience in system design, development, and real-world application architecture.

Technical Skills: Proficiency in Python and Django is mandatory. Candidates must have full-stack experience with a strong backend emphasis, including heavy API development and experience with TypeScript and MySQL.

Education: A formal degree is not required. Experience and technical skill are prioritized.

Preferred Qualifications

  • Experience in healthcare technology, clinical laboratory, or genomics industries.
  • Knowledge of AWS-native environments and cloud platforms.
  • Familiarity with containerization, Kubernetes, or infrastructure-as-code tools like Terraform.
  • Experience designing and maintaining API platforms that serve multiple internal consumers.
  • Familiarity with AI development tools such as Claude or Codex.

Thank You

Ranjeet Kumar | 1Point System LLC

Senior Technical Recruiter
• Email: ranjeet@1pointsys.com • Fax: 803-832-7973 • www.1pointsys.com

https://www.linkedin.com/in/ranjeet-kumar-829a4525b/

If you are unable to reach me directly, please feel free to contact my supervisor at ashish.trivedi@1pointsys.com . They will be able to assist you with any inquiries or provide the support you need.


115 Stone Village Drive • Suite C • Fort Mill, SC • 29708

         An E-Verified company | An Equal Opportunity Employer