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Senior Prompt Engineering Jobs in Delaware (NOW HIRING)

Director, AI Product Development

Wilmington, DE · On-site

$226K - $236K/yr

Familiarity with LLMs, prompt engineering, RAG architectures, and/or agentic frameworks (e.g ... Strong executive communication skills; comfortable presenting product roadmaps and cases to senior ...

... programming adjustments to hearing devices, and maintains member's digital file in the office management system. Rings orders and collects payment when necessary. * Provides and ensures prompt and ...

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Senior Prompt Engineering information

What is a senior prompt engineer?

A Senior Prompt Engineer is a specialist who designs, develops, and optimizes prompts to interact effectively with artificial intelligence language models, such as ChatGPT or other generative AI systems. They leverage deep understanding of AI behavior and natural language processing to create instructions that yield accurate, relevant, and safe outputs. Senior Prompt Engineers may also lead teams, establish best practices, and collaborate with product, engineering, and research teams to improve AI performance and user experience.

What are the key skills and qualifications needed to thrive as a senior prompt engineer, and why are they important?

To excel as a Senior Prompt Engineer, you need strong expertise in natural language processing (NLP), machine learning principles, and experience with large language models, typically supported by a degree in computer science or a related field. Proficiency with programming languages like Python, frameworks such as TensorFlow or PyTorch, and prompt design tools is essential, as are any relevant certifications in AI or data science. Exceptional analytical thinking, creativity, and communication skills help in crafting effective prompts and collaborating with cross-functional teams. These competencies ensure the development of high-quality AI solutions that meet user requirements and drive innovation.

What are some common challenges faced by senior prompt engineers when collaborating with cross-functional teams?

Senior Prompt Engineers often work closely with data scientists, product managers, and software engineers to develop effective AI prompts. A common challenge is ensuring clear communication about technical constraints and user requirements, as team members may have varying levels of familiarity with prompt engineering concepts. Balancing creativity with practical limitations—such as model capabilities and ethical guidelines—requires active collaboration and adaptability. Additionally, aligning prompt design with evolving project goals can be complex, so strong project management and interpersonal skills are essential for success in this role.

What is the difference between Senior Prompt Engineering vs Prompt Engineer?

AspectSenior Prompt EngineeringPrompt Engineer
CredentialsTypically requires experience in AI, NLP, and related certificationsEntry to mid-level skills in AI and prompt design
Work EnvironmentAdvanced projects, leadership roles, strategic planningHands-on prompt creation, testing, and optimization
Industry UsageUsed in organizations developing AI models and NLP applicationsCommon in AI startups, research labs, and tech companies

Senior Prompt Engineering involves leading complex AI projects, designing advanced prompts, and mentoring teams, while Prompt Engineers focus on creating and refining prompts for specific applications. The senior role requires more experience and strategic oversight, whereas the prompt engineer role is more hands-on and task-focused.

Are senior prompt engineers still in demand?

Senior prompt engineers are increasingly in demand as organizations seek expertise in designing effective prompts for AI models like GPT. Their skills in natural language processing, machine learning, and AI tool integration are valuable across industries, and demand is expected to grow with the expansion of AI applications.

What are the most commonly searched types of Prompt Engineering jobs in Delaware?

The most popular types of Prompt Engineering jobs in Delaware are:

What are popular job titles related to Senior Prompt Engineering jobs in Delaware?

For Senior Prompt Engineering jobs in Delaware, the most frequently searched job titles are:

What cities in Delaware are hiring for Senior Prompt Engineering jobs?

Cities in Delaware with the most Senior Prompt Engineering job openings:

Director, AI Product Development

AstraZeneca

Wilmington, DE • On-site

$226K - $236K/yr

Full-time

Posted 16 days ago


AstraZeneca rating

8.4

Company rating: 8.4 out of 10

Based on 45 frontline employees who took The Breakroom Quiz

23rd of 86 rated pharmaceutical


Job description

Make a greater impact on lives through a digitally enabled enterprise.

We are working towards our aspiration of shaping the future of Pharma. Backed by investment at every step, we harness the latest technology, data, and innovative ways of working to introduce new approaches that put Digital at AstraZeneca's heart.

Be part of a chapter that's still being written. Trusted and empowered to change the way things are done, with the tools and support to get you there. Here we are free to unleash our curiosity and turn thinking into reality where smart risks and quick decisions come together to power disruption and innovation.

Office Locations: This is an on-site, office-based role. Please consider the following AZ US HUB locations - Wilmington, DE

This is a product leadership role: you will own the end-to-end lifecycle of AI-powered applications that go into the hands of field and headquarters teams, driving decisions that affect patients and brands at scale.

The Role:

The Director, AI Product Developmentispart oftheAI for Commercial (AIC) team within the newly founded Enterprise AI organization. You will lead the design, build, launch, and adoption of GenAI and ML-powered products that serveGlobal and US functions includingcommercial, medical,market access, and patient programs. You define the roadmap, drive cross-functional execution, and are accountable for measured business impact.

Key Responsibilities

  • Own the full AI product lifecycle: from problem definition andcustomerresearch throughAIdevelopment, UX design, deployment, adoption, and measurement. This means shipping products, not delivering reports.

  • Lead GenAI and agentic AI product development. Define product requirements and functional specifications for AI-powered applications, agentic workflows, and ML-driven tools serving medical, commercial, and field teams.

  • Translate business questions into product requirements. Partner with Marketing, Medical Affairs,GIBEX, Field Operations, and IT to align product capabilities with brandobjectives, field workflows, and launch timelines.

  • Partner with technicaldeliveryleads, engineering, and data science teams to translate requirements into scalable and governed solutions, ensure high-quality, timely execution. Establish clear RACI,maintainalignment on priorities, and drive accountability across a cross-functional delivery model.

  • Drive adoption andimpactmeasurement. Define success criteria beforelaunch; track usage, output quality, and downstream business impact post-launch. Communicate results to leadership with clarity.

  • Operate within enterprise AI governance. Navigate compliance requirements, data access controls, vendor management, and IT approval processes. Ensure all products are deployed responsibly and withappropriate documentation.

  • Stay current with GenAI, agentic AI, and pharma AI trends.Identifyemerging capabilities with strategic fit, pilot solutions with speed and rigor, and champion a platform-centric approach that enables reuse, scalability, and accelerated deployment across functions and markets.

MinimumRequirements

  • Bachelor's degree in a quantitative field (Computer Science, Statistics, Engineering, Economics, or equivalent); advanced degree preferred

  • 7+ years of experience building and shipping data science or AI products in a commercial setting; 3+ years of experiencein building Gen AI tools and platforms.

  • Demonstrated experience owning an AI product end-to-end: requirements, development, deployment, and post-launch measurement

  • Familiarity with LLMs, prompt engineering, RAG architectures, and/or agentic frameworks (e.g.,LangChain,LlamaIndex, or similar)

  • Fluency in Python and ML/AI tooling; experience with cloud platforms (AWS, Azure, or GCP)

  • Strong product thinking: ability to define user needs, write clear requirements, prioritize a backlog, and communicate tradeoffs to customers

  • 3+ years in Pharmaceutical or Life Sciences; familiarity with commercial data and field-facing workflows

Desirable Requirements

  • Experience building GenAI products under enterprise governance requirements

  • Background spanning multiple functions: Commercial, Medical Affairs, Market Access, or Insights & Analytics

  • Demonstrated ability to drive user adoption: training, change management, and usage analytics

  • Experience managing external suppliers and consultants against defined deliverables and timelines

  • Strong executive communication skills; comfortable presenting product roadmaps and cases to senior leadership in a matrixed organization

When we put unexpected teams in the same room, we unleash bold thinking with the power to encourage life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Are you ready to bring new insights and fresh thinking to the table?Fantastic! We have one seat available, and we hope it's yours. Apply today.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

Date Posted

20-Aug-2026

Closing Date

02-Sep-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.


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About AstraZeneca

Sourced by ZipRecruiter

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. A place built on courage, curiosity and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team. Make a meaningful impact that brings real benefits to society. By applying your knowledge of data, you will help to redefine our industry and ultimately save lives. Work with experts who share a common goal: to accelerate the potential of medicines and the science of tomorrow.

Industry

Pharmaceutical product wholesalers and pharmaceutical and medicine manufacturing

Company size

10,000+ Employees

Headquarters location

Cambridge, Cambridgeshire, GB