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Senior Program Manager Jobs in Cambridge, MA (NOW HIRING)

Artis BioSolutions

Senior Program Manager

Watertown, MA

$140K - $165K/yr

The Senior Program Manager has an in-depth understanding of the processes and systems required to manage complex programs and projects, including extensive experience with Smartsheet, along with a ...

Astrion

Senior Program Manager

Hanscom Air Force Base, MA · On-site

$145K - $155K/yr

Overview SENIOR PROGRAM MANAGER LOCATION: Hanscom AFB, MA SALARY RANGE : $145,000 - $155,000 annually* *depending on experience, certifications, and qualifications JOB STATUS: Full-time;salaried ...

Astrion

Senior Program Manager

Hanscom Air Force Base, MA · On-site

$120K - $140K/yr

Overview Senior Program Manager WORK LOCATION :Hanscom AFB, MA Salary Range :$120,000-$140,000* *depen ding on experience, certifications, and qualifications JOB STATUS: Full-time; Salaried Clearance:

Harvard University

Senior Program Manager

Boston, MA · On-site

$57/hr

The Senior Program Manager is a key administrative and strategic partner to the Principal Investigators in NSAPH focused on environmental and public health applications and state-of-the-art causal ...

Harvard University

Senior Program Manager

Boston, MA · On-site

$126K - $126K/yr

The Senior Program Manager is a key administrative and strategic partner to the Principal Investigators in NSAPH focused on environmental and public health applications and state-of-the-art causal ...

Mimecast Limited

Senior Program Manager

Lexington, MA · On-site

$124 - $186/hr

Senior Program Manager***Product Operations -- Lexington, MA, US*Mimecast is looking for a Senior Program Manager to drive our new features and products from readiness through market launch. You'll ...

Astrion

Senior Program Manager

Hanscom Air Force Base, MA · On-site

$140K - $150K/yr

Overview SENIOR PROGRAM MANAGER LOCATION: Hanscom AFB, MA SALARY RANGE : $140,000 -$150,000 annually *depending on experience, certifications, and qualifications JOB STATUS: Full-time;salaried ...

Applied Research Solutions

Senior Program Manager

Bedford, MA · On-site

$122K - $122K/yr

Applied Research Solutions is seeking a Senior Program Manager to provide support to the Command, Control, Communications, and Battle Management Division (C3BM). Command, Control, Communications, and ...

Astrion

Senior Program Manager

Hanscom Air Force Base, MA · On-site

$140K - $150K/yr

Overview SENIOR PROGRAM MANAGER LOCATION: Hanscom AFB, MA SALARY RANGE : $140,000 -$150,000 annually *depending on experience, certifications, and qualifications JOB STATUS: Full-time;salaried ...

Harvard University

Senior Program Manager

Cambridge, MA

$127K - $128K/yr

The Senior Program Manager for NPLI serves as a senior client-facing program and operations lead responsible for managing NPLI's residential and custom program engagements from inquiry through ...

Harvard University

Senior Program Manager

Cambridge, MA · On-site

$57/hr

The Senior Program Manager for NPLI serves as a senior client-facing program and operations lead responsible for managing NPLI's residential and custom program engagements from inquiry through ...

Winaxis

SENIOR PROGRAM MANAGER

Burlington, MA · On-site

$126K - $126K/yr

Job Summary - Senior Program Manager (Technical Program Manager - Digital Commerce Platform Implementation) - Lead end-to-end digital commerce platform implementation programs, handling risks ...

Applied Research Solutions

Senior Program Manager

Bedford, MA · On-site

$122K - $122K/yr

ARS is seeking a Senior Program Manager providing support to the Command, Control, Communications and Battle Management Division (C3BM). Command, Control, Communications, and Battle Management (C3BM ...

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All JobsProgram JobsSenior Program Manager JobsSenior Program Manager Jobs in Cambridge, MA

Senior Program Manager information

See Cambridge, MA salary details

$42.6K

$125.9K

$170K

How much do senior program manager jobs pay per year?

As of Aug 27, 2026, the average yearly pay for senior program manager in Cambridge, MA is $125,860.00, according to ZipRecruiter salary data. Most workers in this role earn between $126,800.00 and $127,300.00 per year, depending on experience, location, and employer.

What is a senior program manager?

A senior program manager can work in many industries, including healthcare, construction, and technology, to improve the efficiency and profitability of a business or organization. As a senior program manager, your job duties involve using analytical skills to manage a project while overseeing a team. You organize resources, stay within budget, use SDLC guidelines, assess project risk, provide quality control to meet goals, and report on development. Minimum qualifications include a bachelor’s degree and industry experience, but an MBA specializing in project management can give you a competitive edge. Desired skills include leadership, organization, and the ability to conduct research. Having a diverse business background is also beneficial for this career.

How does a senior program manager typically collaborate with cross-functional teams to ensure project success?

A Senior Program Manager regularly works with cross-functional teams by facilitating communication among stakeholders, aligning project goals, and resolving conflicts that may arise between departments. They often lead meetings, set clear expectations, and provide updates to ensure all teams are on track with deliverables and timelines. Building strong relationships with product, engineering, finance, and other relevant teams is crucial to proactively identify and address potential risks. This collaborative approach not only streamlines workflows but also fosters a culture of accountability and shared ownership of program outcomes.

What are the key skills and qualifications needed to thrive as a senior program manager, and why are they important?

To thrive as a Senior Program Manager, you need expertise in project management, strategic planning, and cross-functional leadership, often supported by a bachelor's or master's degree and significant management experience. Familiarity with tools such as Microsoft Project, Jira, and project management certifications like PMP or Agile are typically required. Exceptional communication, stakeholder management, and problem-solving skills set top performers apart in this position. These skills are crucial for aligning teams, delivering complex projects on time, and driving organizational objectives.

What is the difference between Senior Program Manager vs Project Manager?

AspectSenior Program ManagerProject Manager
CredentialsTypically requires a bachelor's degree, PMP or PgMP certification, extensive experience in program managementUsually requires a bachelor's degree, PMP certification often preferred, less extensive experience needed
Work EnvironmentOversees multiple related projects within a program, strategic focusManages individual projects, tactical focus
Employer & Industry UsageCommon in large corporations, tech, healthcare, and finance sectorsWidely used across industries for specific project delivery

The Senior Program Manager focuses on managing multiple projects aligned with organizational goals, requiring strategic oversight and extensive experience. In contrast, the Project Manager handles individual projects, ensuring timely delivery and scope management. Both roles are vital but differ mainly in scope and complexity.

How much does a senior program manager make in the US?

A senior program manager in the US typically earns between $100,000 and $150,000 annually, with variations based on industry, location, and experience. Many senior program managers also receive bonuses and benefits, and strong project management skills and certifications like PMP can influence salary levels.
More about Senior Program Manager jobs

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For Senior Program Manager jobs in Cambridge, MA, the most frequently searched job titles are:

What job categories do people searching Senior Program Manager jobs in Cambridge, MA look for?

The top searched job categories for Senior Program Manager jobs in Cambridge, MA are:

What cities near Cambridge, MA are hiring for Senior Program Manager jobs?

Cities near Cambridge, MA with the most Senior Program Manager job openings:

Senior Program Manager jobs near you
Infographic showing various Senior Program Manager job openings in Cambridge, MA as of August 2026, with employment types broken down into 100% Full Time. Highlights an 60% In-person, and 40% Hybrid job distribution, with an average salary of $125,860 per year, or $60.5 per hour.

Senior Program Manager

Artis BioSolutions

Watertown, MA

$140K - $165K/yr

Full-time

Re-posted 10 days ago

Job description

We are seeking a self-driven, team-oriented, and entrepreneurial-minded Senior Program Manager to join Landmark Bio. The Senior Program Manager has an in-depth understanding of the processes and systems required to manage complex programs and projects, including extensive experience with Smartsheet, along with a functional understanding of the technical aspects of cell and gene therapy programs and awareness of Landmark Bio's business objectives.

The Senior Program Manager will support cross-functional program execution by driving operational coordination, maintaining program management tools and documentation, and serving as a key liaison between internal teams and external clients. This role is responsible for managing timelines, dashboards, communications, and process improvements while ensuring programs are executed efficiently and effectively.

Responsibilities
  • Support the planning, coordination, and execution of internal and client-facing programs
  • Develop and maintain program timelines, schedules, dashboards, and risk registers with support from senior program managers
  • Coordinate program materials and shared resources, escalating constraints and risks as appropriate
  • Generate and maintain documentation for program scope changes and client communications
  • Assist with capturing and sharing lessons learned across programs to improve operational efficiency
  • Create and update presentations for team meetings, leadership reviews, and client discussions
  • Serve as a Smartsheet super user for the organization, creating, managing, and optimizing complex workflows, automations, dashboards, and reporting tools
  • Develop and maintain program management resources including trackers, templates, dashboards, presentation materials, and other operational tools
  • Evaluate and recommend process improvements to enhance team collaboration, visibility, and efficiency
  • Collaborate cross-functionally on new system evaluations, tool implementations, and training initiatives
  • Maintain internal Microsoft Teams sites and external SharePoint client sites to ensure documentation is organized, current, and accessible
  • Archive program documentation at the close of programs in accordance with internal procedures
  • Own and maintain program management documentation including:
    • Program charters
    • Program plans and schedules
    • RACI matrices
    • Risk registers
    • Business requirements
    • Policies and procedures
    • Training materials
  • Ensure all documentation is accurate, complete, version-controlled, and properly stored
  • Serve as the primary point of contact for assigned clients
  • Coordinate and manage client meetings, teleconferences, and onsite visits
  • Prepare agendas, meeting minutes, action items, and follow-up communications
  • Build collaborative relationships with internal stakeholders and external partners to support successful program delivery
  • Assist in training personnel on evolving program management tools and systems
  • Develop training materials including slide decks, guides, and reference documentation
Qualifications
  • BS degree with 7+ years relevant experience (GMP pharmaceutical, biologics, and/or cell and gene therapy field) is required
  • PMP certification desired
  • High degree of proficiency in Smartsheet is required, including advanced skills in workflow design and implementation, template creation and management, user training and support, and reporting and analytics
  • Strong communication, problem solving, planning, and project management skills
  • Ability to support more than one project of a reasonable size simultaneously
$140,000 - $165,000 a year
Landmark Bio is dedicated to translating cutting-edge research into life-changing therapies. The company provides CMC development and GMP manufacturing capabilities for cell and gene therapies and other novel modalities, and partners with academic, biotech, and industry collaborators to advance next-generation manufacturing technologies.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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