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Senior Manager Statistical Programming Jobs in Boston, MA

Senior Director, Biostatistics

Waltham, MA ยท On-site

$250 - $290/hr

As a senior statistical leader and crossโ€‘functional partner, this role leads statistical ... Management, Statistical Programming, Translational Medicine, Program Management, and other ...

Posted today

Senior Director Biostatistics

Boston, MA ยท On-site

$250K - $300K/yr

... manage statistical efforts for multiple clinical studies across a clinical program; provide leadership and guidance to other members of biostatistics and statistical programming team * Formulate ...

... manage statistical efforts for multiple clinical studies across a clinical program; provide leadership and guidance to other members of biostatistics and statistical programming team * Formulate ...

Manage the statistical programming function and ensure delivery of high-quality datasets and ... senior leadership team, delivering timely biometrics insights and presentation support for high ...

Head of Biometrics

Watertown, MA ยท On-site

$310K - $395K/yr

Manage the statistical programming function and ensure delivery of high-quality datasets and ... senior leadership team, delivering timely biometrics insights and presentation support for high ...

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Senior Manager Statistical Programming information

See Boston, MA salary details

$26.1K

$107.6K

$181.4K

How much do senior manager statistical programming jobs pay per year?

As of Jul 19, 2026, the average yearly pay for senior manager statistical programming in Boston, MA is $107,563.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,500.00 and $116,200.00 per year, depending on experience, location, and employer.

What are Senior Manager Statistical Programming?

A Senior Manager Statistical Programming is a leadership role in the field of clinical research and biostatistics, typically within the pharmaceutical, biotechnology, or contract research organization (CRO) industries. This professional oversees teams of statistical programmers responsible for analyzing clinical trial data, ensuring data accuracy, and delivering high-quality statistical outputs for regulatory submissions. The role involves project management, resource allocation, mentoring staff, and collaborating with cross-functional teams to ensure compliance with regulatory standards and timelines.

What is the difference between Senior Manager Statistical Programming vs Statistical Programmer?

AspectSenior Manager Statistical ProgrammingStatistical Programmer
CredentialsBachelor's/Master's in Biostatistics, Computer Science, or related field; often with management experienceBachelor's or Master's in Biostatistics, Statistics, or related field
Work EnvironmentLeads teams, manages projects, collaborates with cross-functional teamsPerforms data analysis, programming, and validation tasks under supervision
Employer & Industry UsagePharmaceutical, biotech companies, CROs, clinical researchPharmaceutical, biotech, clinical research organizations

The main difference is that Senior Manager Statistical Programming oversees teams and manages projects, while Statistical Programmers focus on executing data analysis and programming tasks. The senior role involves leadership responsibilities, whereas the programmer role is more technical and task-oriented.

What are the key skills and qualifications needed to thrive as a Senior Manager Statistical Programming, and why are they important?

To thrive as a Senior Manager Statistical Programming, you need expertise in biostatistics, programming languages like SAS or R, and experience with clinical trial data, typically supported by an advanced degree in a quantitative field. Familiarity with regulatory requirements (e.g., CDISC standards), clinical data management systems, and project management tools is essential. Strong leadership, communication, and problem-solving skills help you lead teams and liaise with cross-functional stakeholders. These skills ensure accurate, compliant data analyses and effective team management for successful clinical trial outcomes.

How does a Senior Manager Statistical Programming typically collaborate with cross-functional teams in clinical research projects?

A Senior Manager Statistical Programming plays a pivotal role in coordinating with biostatisticians, clinical data managers, and medical writers to ensure seamless data flow and analysis throughout clinical trials. They oversee programming teams to deliver statistical outputs, such as tables, listings, and figures, while maintaining compliance with regulatory standards. Regular meetings and clear communication are essential, as the Senior Manager must interpret project requirements and translate them into actionable programming tasks, ensuring timelines and quality standards are met. This collaborative environment fosters continuous learning and problem-solving, as cross-functional input is vital for addressing complex data challenges.
What are popular job titles related to Senior Manager Statistical Programming jobs in Boston, MA? For Senior Manager Statistical Programming jobs in Boston, MA, the most frequently searched job titles are:
What job categories do people searching Senior Manager Statistical Programming jobs in Boston, MA look for? The top searched job categories for Senior Manager Statistical Programming jobs in Boston, MA are:
What cities near Boston, MA are hiring for Senior Manager Statistical Programming jobs? Cities near Boston, MA with the most Senior Manager Statistical Programming job openings:
Principal Statistical Programmer

Principal Statistical Programmer

Vertex Pharmaceuticals

Boston, MA โ€ข On-site

$149K - $223K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 21 days ago


Job description

Job Description
General Summary:
The Principal Statistical Programmer works with management to delegate tasks appropriately, track progress, and provide expert technical support to team members. In addition, the Principal Statistical Programmer is a designated member of clinical sub-team(s) in the role of project lead Statistical Programmer.
Key Duties and Responsibilities:
  • Works regularly with advanced features of SAS (including interfacing ability with other software applications and operating system tools)
  • Performs quality control checks of SAS code and output produced by other Statistical Programmers to ensure accuracy and consistency within group
  • Demonstrates in-depth knowledge of clinical development and medical data
  • Solves complex clinical trial reporting problems and demonstrates technical proficiency and exercises judgment in supporting daily operations and ensuring that study tasks are completed accurately and in a timely manner
  • Engages with a variety of other functions, including Statistical Programmers, Biostatisticians, Data Management, and other departments engaged in providing data and submission-related activities, often at Senior Management levels
  • Creates all files, documents, and analyses necessary to support an electronic submission in eCTD format, including ISS/ISE
  • Provides leadership to ensure compliance with Vertex SOP'S and FDA/ICH/GCP regulations
  • Provides technical and project management skills to create, review, and approve documentation required to support data analysis, reporting, and CDlSC data submission
  • Participates in project management cross-functional teams that work on standard operating procedures, guidelines, process improvements, system validation and acquisition, customization, and integration of new tools and technologies

Knowledge and Skills:
  • Proficiency in all SAS language, procedures, and functions commonly used in clinical trial reporting including the Macro language, BASE SAS, SAS/STAT and SAS/GRAPH
  • Intermediate knowledge of CDISC Standards
  • Intermediate knowledge of clinical trials
  • Regulatory submission experiences
  • Effective communication (written and verbal) skills to explain difficult information

Education and Experience:
  • Bachelors degree in a Scientific Discipline
  • Typically requires 5+ for M.S. or above and 8+ years for B.S. years of work experience in Biotech, Pharmaceuticals or Clinical Research Organization

Pay Range:
$149,200 - $223,800
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Remote-Eligible
Flex Eligibility Status:
In this Remote-Eligible role, you can choose to be designated as:
1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select
2. Hybrid: work remotely up to two days per week; or select
3. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Remote
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com