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Senior Machine Learning Scientist Jobs (NOW HIRING)

Senior Machine Learning Scientist

Seattle, WA · On-site

$104K - $142K/yr

Your Impact We are seeking highly skilled and innovative Machine Learning Scientists to join our AI ... PhD and with +5 years for ML Scientist, +8 years for Sr. ML Scientist, +10 years for Principal ML ...

Your Impact We are seeking highly skilled and innovative Machine Learning Scientists to join our AI ... PhD and with +5 years for ML Scientist, +8 years for Sr. ML Scientist, +10 years for Principal ML ...

$85K - $116K/yr

Machine Learning Scientist What you will do Let'sdo this.Let'schange the world.Within Amgen's Research and Development organization, the Therapeutic Protein Design (TPD) team supports the broad goal ...

Your Impact We are seeking highly skilled and innovative Machine Learning Scientists to join our AI ... PhD and with +5 years for ML Scientist, +8 years for Sr. ML Scientist, +10 years for Principal ML ...

Sr Machine Learning Scientist

Thousand Oaks, CA · On-site +1

$96K - $131K/yr

Machine Learning Scientist What you will do Let's do this. Let's change the world. Within Amgen's Research and Development organization, the Therapeutic Protein Design (TPD) team supports the broad ...

Senior Machine Learning Scientist

Austin, TX · On-site

$90K - $123K/yr

We are currently seeking an experienced, dynamic, organized, self-starter to join as a Senior Machine Learning Scientist for our Consulting and Digital Transformation (CDx) line of business. Key ...

Senior Machine Learning Scientist

Seattle, WA · On-site

$104K - $142K/yr

Your Impact We are seeking highly skilled and innovative Machine Learning Scientists to join our AI ... PhD and with +5 years for ML Scientist, +8 years for Sr. ML Scientist, +10 years for Principal ML ...

Senior Machine Learning Scientist

Boston, MA · On-site

$99K - $135K/yr

Your Impact We are seeking highly skilled and innovative Machine Learning Scientists to join our AI ... PhD and with +5 years for ML Scientist, +8 years for Sr. ML Scientist, +10 years for Principal ML ...

Machine Learning Scientist What you will do Let'sdo this.Let'schange the world.Within Amgen's Research and Development organization, the Therapeutic Protein Design (TPD) team supports the broad goal ...

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Senior Machine Learning Scientist information

See salary details

$66.5K

$110.5K

$164.5K

How much do senior machine learning scientist jobs pay per year?

As of Jul 24, 2026, the average yearly pay for senior machine learning scientist in the United States is $110,545.00, according to ZipRecruiter salary data. Most workers in this role earn between $91,500.00 and $125,000.00 per year, depending on experience, location, and employer.

What is the difference between Senior Machine Learning Scientist vs Data Scientist?

AspectSenior Machine Learning ScientistData Scientist
CredentialsMaster's or PhD in CS, ML, or related fieldBachelor's or Master's in CS, Statistics, or related field
Work EnvironmentFocus on developing ML models, algorithms, and researchData analysis, visualization, and business insights
Industry UsageUsed in AI-driven companies, tech firms, research labsCommon across industries for data analysis and reporting

While both roles involve working with data, Senior Machine Learning Scientists focus on developing advanced ML models and algorithms, often requiring research and deep technical expertise. Data Scientists typically analyze data to generate insights and support decision-making. The roles overlap but differ mainly in technical depth and focus area.

What are Senior Machine Learning Scientists?

Senior Machine Learning Scientists are experienced professionals who design, develop, and implement advanced machine learning models to solve complex business or research problems. They are responsible for leading projects, mentoring junior team members, and staying updated on the latest AI and data science technologies. Their work often involves analyzing large datasets, selecting the right algorithms, and optimizing model performance for real-world applications. In addition to technical expertise, they often collaborate cross-functionally to align machine learning solutions with organizational goals.

What are the key skills and qualifications needed to thrive as a Senior Machine Learning Scientist, and why are they important?

To thrive as a Senior Machine Learning Scientist, you need expertise in machine learning algorithms, statistical analysis, programming (usually in Python or R), and an advanced degree (often a Ph.D.) in a quantitative field. Experience with tools such as TensorFlow, PyTorch, scikit-learn, cloud platforms, and version control systems is typically expected, along with knowledge of deploying models in production environments. Exceptional problem-solving, communication, and leadership skills help you translate complex data insights into actionable business solutions and mentor junior team members. These skills are crucial for developing innovative models, ensuring robust deployment, and driving impactful data-driven decisions.

What are some common challenges Senior Machine Learning Scientists face when deploying models to production environments?

Senior Machine Learning Scientists often encounter challenges such as ensuring model scalability, maintaining model performance over time, and addressing data drift once models are deployed to production. Collaborating closely with engineering and operations teams is crucial to streamline deployment pipelines and monitor models for real-world reliability. It’s also important to communicate findings and potential risks to stakeholders, and to regularly update models based on new data or business requirements. These aspects make strong cross-functional teamwork and problem-solving skills essential in this role.
More about Senior Machine Learning Scientist jobs
What cities are hiring for Senior Machine Learning Scientist jobs? Cities with the most Senior Machine Learning Scientist job openings:
What are the most commonly searched types of Machine Learning Scientist jobs? The most popular types of Machine Learning Scientist jobs are:
What states have the most Senior Machine Learning Scientist jobs? States with the most job openings for Senior Machine Learning Scientist jobs include:
Infographic showing various Senior Machine Learning Scientist job openings in the United States as of July 2026, with employment types broken down into 1% As Needed, 72% Full Time, 25% Part Time, 1% Temporary, and 1% Contract. Highlights an 86% Physical, 2% Hybrid, and 12% Remote job distribution, with an average salary of $110,545 per year, or $53.1 per hour.
Senior Machine Learning Scientist I, Drug Discovery Analytics

Senior Machine Learning Scientist I, Drug Discovery Analytics

Revolution Medicines

Redwood City, CA • Hybrid

$112K - $153K/yr

Other

Posted 28 days ago


Job description

The Opportunity:

We are seeking a Senior Machine Learning Scientist to help accelerate drug discovery through advanced analytics and artificial intelligence. This role will develop predictive models and analytical methods that transform complex biological and chemical datasets into actionable insights that guide research decisions.

The Senior Machine Learning Scientist will work at the interface of data science, chemistry, and biology to support target discovery, compound optimization, and translational research. This position requires both strong machine learning expertise and the ability to collaborate effectively with experimental scientists to solve real-world scientific problems.

The successful candidate will contribute to building a data-driven discovery ecosystem where data, analytics, and experimentation continuously inform and accelerate one another.
Key responsibilities include:

  • Develop Predictive Models for Drug Discovery.

  • Independently Design and implement machine learning models to predict compound activity, selectivity, and developability.

  • Identify and Develop predictive frameworks for ADME/Tox, target engagement, and phenotypic screening outcomes.

  • Apply advanced modeling approaches including deep learning, graph neural networks, and ensemble methods.

  • Evaluate model performance and apply appropriate validation strategies.

  • Work with data engineers and ML engineers to integrate models into discovery pipelines.

  • Analyze Complex Scientific Data.

  • Perform exploratory data analysis on chemical, biological, and phenotypic datasets.

  • Integrate heterogeneous datasets including:

  • Chemical structure and screening data.

  • Structural biology and molecular simulation outputs.

  • Collaborate with Research Scientists.

  • Partner with medicinal chemists to support compound design and lead optimization.

  • Work with biologists to interpret experimental results and identify new target opportunities.

  • Translate scientific questions into computational modeling strategies.

Required Skills, Experience and Education:

  • PhD in machine learning, computational biology, computational chemistry, computer science, statistics, or a related quantitative field.

  • 6-10 years of experience applying machine learning or advanced analytics to scientific datasets.

  • Python and scientific computing libraries (NumPy, Pandas, SciPy).

  • Machine learning frameworks (PyTorch, TensorFlow, scikit-learn).

  • Model development, validation, and evaluation methods.

  • Data visualization and exploratory analysis.

  • Experience working with noisy and incomplete experimental datasets.

Preferred Skills:

  • Cheminformatics or molecular modeling tools (RDKit, OpenEye, etc.).

  • Multi-omics data analysis.

  • Cloud computing environments.

  • MLOps or scalable model deployment. 

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