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Senior Machine Learning Engineer Jobs in Poway, CA

Sr. AI/ML Engineer - Life Science

San Diego, CA · On-site

$110K - $152K/yr

The Sr. Machine Learning Engineer is largely self-driven, working in collaboration with others on one or more projects which are extremely complex in scope. This role is responsible for successfully ...

Sr. AI/ML Engineer - Life Science

San Diego, CA · On-site

$110K - $152K/yr

The Sr. Machine Learning Engineer is largely self-driven, working in collaboration with others on one or more projects which are extremely complex in scope. This role is responsible for successfully ...

Sr. AI/ML Engineer - Life Science

San Diego, CA · On-site

$110K - $152K/yr

The Sr. Machine Learning Engineer is largely self-driven, working in collaboration with others on one or more projects which are extremely complex in scope. This role is responsible for successfully ...

* Own model training and post-training pipelines end to end: SFT, RLHF, PPO, DPO, and reward model training in PyTorch * Build and maintain the infrastructure around RL training: rollout collection ...

* Own model training and post-training pipelines end to end: SFT, RLHF, PPO, DPO, and reward model training in PyTorch * Build and maintain the infrastructure around RL training: rollout collection ...

Company Qualcomm Incorporated Job Area Engineering Group, Engineering Group > Machine Learning Engineering General Summary We are seeking a highly skilled Core ML Engineer to design, develop, and ...

Senior Engineer - Machine Learning

San Diego, CA · On-site

$110K - $152K/yr

Engineering Group, Engineering Group > Machine Learning Engineering General Summary: We are seeking a highly skilled Core ML Engineer to design, develop, and optimize machine learning systems that ...

Showing results 41-60

Senior Machine Learning Engineer information

See Poway, CA salary details

$60.9K

$129.5K

$187.7K

How much do senior machine learning engineer jobs pay per year?

As of Sep 7, 2026, the average yearly pay for senior machine learning engineer in Poway, CA is $129,463.00, according to ZipRecruiter salary data. Most workers in this role earn between $106,900.00 and $146,800.00 per year, depending on experience, location, and employer.

What does a senior machine learning engineer do?

A Senior Machine Learning Engineer designs, develops, and implements machine learning models to solve complex problems. They are responsible for selecting appropriate algorithms, preprocessing data, and optimizing model performance. Additionally, they collaborate with data scientists, software engineers, and product teams to integrate machine learning solutions into production systems. Senior engineers also mentor junior team members and contribute to setting technical direction for machine learning projects.

What are some common challenges senior machine learning engineers face when deploying models to production, and how can they be addressed?

Senior Machine Learning Engineers often encounter challenges related to model scalability, maintaining performance in real-world scenarios, and ensuring reliable integration with existing systems. Addressing these challenges typically involves thorough testing, implementing robust monitoring for model drift, and collaborating closely with DevOps and software engineering teams to streamline deployment pipelines. Staying updated on best practices in MLOps and adopting tools for automated deployment and monitoring can greatly improve the reliability and efficiency of production models.

What are the key skills and qualifications needed to thrive as a senior machine learning engineer, and why are they important?

To thrive as a Senior Machine Learning Engineer, you need advanced knowledge of machine learning algorithms, statistical modeling, and programming languages like Python or Java, typically supported by a degree in computer science or a related field. Experience with frameworks and tools such as TensorFlow, PyTorch, scikit-learn, and cloud platforms, as well as familiarity with version control and CI/CD systems, is essential. Strong problem-solving, communication, and leadership skills help you collaborate effectively and mentor junior team members. These capabilities are crucial for designing scalable ML solutions and driving impactful results within complex, dynamic projects.

What is the difference between Senior Machine Learning Engineer vs Data Scientist?

AspectSenior Machine Learning EngineerData Scientist
Required CredentialsBachelor's/Master's in CS, ML, or related; experience with ML frameworksBachelor's/Master's in CS, Statistics, or related; strong analytical skills
Work EnvironmentDevelops and deploys ML models in production systemsAnalyzes data, builds models, and provides insights
Industry UsageTech, finance, healthcare, e-commerceResearch, finance, marketing, tech

While both roles require strong technical skills and knowledge of machine learning, Senior Machine Learning Engineers focus more on deploying scalable ML solutions in production environments, whereas Data Scientists primarily analyze data and develop models for insights. The roles often overlap but differ in their core responsibilities and focus areas.

What are the most commonly searched types of Machine Learning Engineer jobs in Poway, CA?

The most popular types of Machine Learning Engineer jobs in Poway, CA are:

What cities near Poway, CA are hiring for Senior Machine Learning Engineer jobs?

Cities near Poway, CA with the most Senior Machine Learning Engineer job openings:

Infographic showing various Senior Machine Learning Engineer job openings in Poway, CA as of August 2026, with employment types broken down into 1% As Needed, 72% Full Time, 25% Part Time, and 2% Contract. Highlights an 86% Physical, 2% Hybrid, and 12% Remote job distribution, with an average salary of $129,463 per year, or $62.2 per hour.

Sr. AI/ML Engineer - Life Science

Abbott

San Diego, CA • On-site

$110K - $152K/yr

Full-time

Re-posted 8 days ago


Abbott rating

7.8

Company rating: 7.8 out of 10

Based on 138 frontline employees who took The Breakroom Quiz

171st of 546 rated manufacturers


Job description

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 115,000 colleagues serve people in more than 160 countries.JOB DESCRIPTION:

Position Overview:


The Sr. Machine Learning Engineer is largely self-driven, working in collaboration with others on one or more projects which are extremely complex in scope. This role is responsible for successfully leading the planning and execution of projects. Working in a team setting, this position applies deep knowledge of advanced artificial intelligence and machine learning algorithms and models to solve complex problems involving biological, genomic, clinical and healthcare data within a setting of advanced cancer screening and precision oncology. This position provides technical leadership at every step of the solution development process, from ideation, design, implementation and deployment. The Lead Machine Learning Engineer will help craft the strategic vision for the application of cutting-edge AI methodologies at Exact Sciences and work as a partner with biostatisticians, bioinformatics scientists, and data scientists to further our goal of helping eradicate cancer by preventing it, detecting it earlier, and guiding personalized treatment.


Essential Duties
Include, but are not limited to, the following:

  • Lead development of perspectives on technology "affordance": what do these advances in AI technology allow us to do (more efficiently and / or more effectively) that we couldn't do before
  • Work with stakeholders to identify, refine, prioritize and formalize requirements for ML- and AI-based solutions to business problems with a focus on bioinformatics, biostatistics and data engineering applications.
  • Collaborate with other ML/AI engineers and relevant partners to provide technical and strategic leadership for the design of software solutions that utilize state-of-the art artificial intelligence and machine learning techniques.
  • Work with other AI and ML engineers and software engineers to lead the implementation and deployment of ML and AI solutions.
  • Set up Agile framework focused on delivering iterative, "rapid" solutions that demonstrate the promise of selected AI technologies.
  • Provide leadership in the development of an AI strategy at Exact Sciences that empowers the team to leverage both existing AI and ML tools and those developed in-house to accelerate and enhance bioinformatics, biostatistics and data science processes and outcomes.
  • Lead internal initiatives to build training resources, develop knowledge bases, and educate on advanced AI and ML technologies and best practices for leveraging them.
  • Lead "AI evangelism" for biostatistics, bioinformatics and data science at Exact Sciences.
  • Assist team to solve complex problems using sophisticated analytical thought to exercise judgement and identify innovative solution
  • Provide mentorship and coaching to more junior level team members.
  • Act as resource and subject matter expert in core team and/or cross-functional meetings.
  • Contribute to the intellectual property portfolio by implementing innovative and creative ideas to solve problems or improve on current methods.
  • Exercise discretion and judgment within broadly defined practices and policies in selecting methods and techniques and evaluation criteria for obtaining and interpreting results.
  • Ability to effectively communicate, influence decision-making, and explain difficult, sensitive, and/or highly complex information to audiences of peers.
  • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
  • Support and comply with the company's Quality Management System policies and procedures.
  • Maintain regular and reliable attendance.
  • Ability to act with an inclusion mindset and model these behaviors for the organization.
  • Ability to work designated schedule.
  • Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 85% of a typical working day.
  • Ability to travel 5% of working time away from work location, may include overnight/weekend travel.

Minimum Qualifications

  • Ph.D in Statistics, Computational Biology, Computer Science, or related quantitative field as outlined in the essential duties, or Master's Degree in Statistics, Computational Biology, Computer Science, or related quantitative field as outlined in the essential duties plus 4 years of relevant experience.
  • 5+ years of experience in statistics, computational biology, applied mathematics, or related quantitative field as outlined in the essential duties.
  • 5+ years of experience with artificial intelligence and machine learning algorithms.
  • Demonstrated experience with and mastery of advanced AI concepts, such as artificial neural networks, deep learning, and reinforcement learning.
  • Demonstrated experience with and mastery of artificial intelligence and machine learning techniques within one or more of the following fields: natural language processing, image processing and computer vision, image and pattern recognition.
  • Demonstrated experience with and mastery of large language models for generative AI and associated concepts, such as transformer architecture and retrieval augmented generation.
  • Strong programming ability with demonstrated experience in Python and one or more associated machine learning frameworks, such as TensorFlow, PyTorch, or SKLearn.
  • Knowledge and experience working with open-source AI models.
  • Excellent communication skills and the ability to explain complex topics to audiences of varied backgrounds.
  • Demonstrated ability to perform the essential duties of the position with or without accommodation.
  • Authorization to work in the United States without sponsorship.

Preferred Qualifications

  • 8+ years of life sciences industry experience working with biological data.
  • 8+ years of industry experience in molecular diagnostics, preferably cancer diagnostics.
  • Expertise in data mining approaches within healthcare settings generating insight from routinely collected healthcare data.
  • Basic knowledge of ML-Ops and processes for managing the versioning and deployment of machine learning models.
  • Scientific understanding of cancer biology

The base pay for this position is

$99,300.00 - $198,700.00

In specific locations, the pay range may vary from the range posted.

JOB FAMILY:Product DevelopmentDIVISION:ONCO Cancer DiagnosticsLOCATION:United States > California : RemoteADDITIONAL LOCATIONS:WORK SHIFT:StandardTRAVEL:Yes, 5 % of the TimeMEDICAL SURVEILLANCE:Not ApplicableSIGNIFICANT WORK ACTIVITIES:Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day), Keyboard use (greater or equal to 50% of the workday)Abbott is an Equal Opportunity Employer of Minorities/Women/Individuals with Disabilities/Protected Veterans.EEO is the Law link - English: http://webstorage.abbott.com/common/External/EEO_English.pdfEEO is the Law link - Espanol: http://webstorage.abbott.com/common/External/EEO_Spanish.pdf

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