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Senior Machine Learning Engineer Jobs in Boston, MA

C the Signs

Senior Machine Learning Engineer

Boston, MA · On-site +1

$133K - $175K/yr

Position Summary The Machine Learning Engineer will be responsible for the end-to-end development and deployment of Large language and machine learning models, with a primary focus on data ...

Sierra Ventures

Machine Learning Engineer

Somerville, MA · On-site

$170 - $200/hr

We're looking for a Senior Machine Learning Engineer to help advance the state of voice understanding at Modulate. In this role, you'll design, train, evaluate, and deploy cutting‑edge machine ...

Capital One

Sr. Lead Machine Learning Engineer

Cambridge, MA · On-site +1

$112K - $147K/yr

Sr. Lead Machine Learning Engineer As a Capital One Machine Learning Engineer (MLE) , you'll be part of an Agile team dedicated to productionizing machine learning applications and systems at scale.

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Senior Machine Learning Engineer information

See Boston, MA salary details

$64.6K

$137.5K

$199.3K

How much do senior machine learning engineer jobs pay per year?

As of Sep 3, 2026, the average yearly pay for senior machine learning engineer in Boston, MA is $137,484.00, according to ZipRecruiter salary data. Most workers in this role earn between $113,500.00 and $155,900.00 per year, depending on experience, location, and employer.

What does a senior machine learning engineer do?

A Senior Machine Learning Engineer designs, develops, and implements machine learning models to solve complex problems. They are responsible for selecting appropriate algorithms, preprocessing data, and optimizing model performance. Additionally, they collaborate with data scientists, software engineers, and product teams to integrate machine learning solutions into production systems. Senior engineers also mentor junior team members and contribute to setting technical direction for machine learning projects.

What are some common challenges senior machine learning engineers face when deploying models to production, and how can they be addressed?

Senior Machine Learning Engineers often encounter challenges related to model scalability, maintaining performance in real-world scenarios, and ensuring reliable integration with existing systems. Addressing these challenges typically involves thorough testing, implementing robust monitoring for model drift, and collaborating closely with DevOps and software engineering teams to streamline deployment pipelines. Staying updated on best practices in MLOps and adopting tools for automated deployment and monitoring can greatly improve the reliability and efficiency of production models.

What are the key skills and qualifications needed to thrive as a senior machine learning engineer, and why are they important?

To thrive as a Senior Machine Learning Engineer, you need advanced knowledge of machine learning algorithms, statistical modeling, and programming languages like Python or Java, typically supported by a degree in computer science or a related field. Experience with frameworks and tools such as TensorFlow, PyTorch, scikit-learn, and cloud platforms, as well as familiarity with version control and CI/CD systems, is essential. Strong problem-solving, communication, and leadership skills help you collaborate effectively and mentor junior team members. These capabilities are crucial for designing scalable ML solutions and driving impactful results within complex, dynamic projects.

What is the difference between Senior Machine Learning Engineer vs Data Scientist?

AspectSenior Machine Learning EngineerData Scientist
Required CredentialsBachelor's/Master's in CS, ML, or related; experience with ML frameworksBachelor's/Master's in CS, Statistics, or related; strong analytical skills
Work EnvironmentDevelops and deploys ML models in production systemsAnalyzes data, builds models, and provides insights
Industry UsageTech, finance, healthcare, e-commerceResearch, finance, marketing, tech

While both roles require strong technical skills and knowledge of machine learning, Senior Machine Learning Engineers focus more on deploying scalable ML solutions in production environments, whereas Data Scientists primarily analyze data and develop models for insights. The roles often overlap but differ in their core responsibilities and focus areas.

What are the most commonly searched types of Machine Learning Engineer jobs in Boston, MA?

The most popular types of Machine Learning Engineer jobs in Boston, MA are:

What are popular job titles related to Senior Machine Learning Engineer jobs in Boston, MA?

For Senior Machine Learning Engineer jobs in Boston, MA, the most frequently searched job titles are:

What job categories do people searching Senior Machine Learning Engineer jobs in Boston, MA look for?

The top searched job categories for Senior Machine Learning Engineer jobs in Boston, MA are:

What cities near Boston, MA are hiring for Senior Machine Learning Engineer jobs?

Cities near Boston, MA with the most Senior Machine Learning Engineer job openings:

Senior Machine Learning Engineer jobs near you
Infographic showing various Senior Machine Learning Engineer job openings in Boston, MA as of August 2026, with employment types broken down into 1% As Needed, 75% Full Time, 22% Part Time, and 2% Contract. Highlights an 88% Physical, 2% Hybrid, and 10% Remote job distribution, with an average salary of $137,484 per year, or $66.1 per hour.

Senior Machine Learning Engineer

C the Signs

Boston, MA • On-site, Remote

$133K - $175K/yr

Full-time

Re-posted 9 days ago

Key responsibilities

  • Preprocess and prepare large healthcare datasets for machine learning model development.

  • Design, train, and fine-tune large language models on healthcare data to address clinical or operational problems.

  • Develop and maintain scalable data and machine learning pipelines for model training, inference, and deployment.

Job description

Position Summary
The Machine Learning Engineer will be responsible for the end-to-end development and deployment of Large language and machine learning models, with a primary focus on data preprocessing, model training, and fine-tuning using large-scale healthcare datasets. This role requires a strong understanding of Large language models, machine learning principles, data engineering, and experience working with sensitive healthcare data.
Key Responsibilities
  • Data Preprocessing: Clean, transform, and prepare large, complex healthcare datasets for machine learning model development. This includes handling missing values, outlier detection, feature engineering, and data normalization. Identify, collect, and curate relevant, industry-specific datasets for model retraining. Format data appropriately for the chosen LLM and training pipeline
  • Model Training & Fine-Tuning: Design, train, and fine-tune various LLMs on extensive healthcare data to solve specific clinical or operational problems. Set up and manage the training environment, including GPU instances and required software. Train and fine-tune pre-trained LLMs on the custom dataset to achieve specific goals. Experiment with and fine-tune hyperparameters such as learning rate, batch size, and training epochs to optimize model performance. Integration of structured + unstructured data (multi-modal/multi-input models)
  • Model Evaluation & Optimization: Evaluate model performance using appropriate metrics, identify areas for improvement, and implement optimization strategies.
  • Pipeline Development: Develop and maintain robust and scalable data and ML pipelines for model training, inference, and deployment.
  • Collaboration: Work closely with data scientists, clinicians, and software engineers to understand requirements, integrate models into production systems, and ensure data privacy and security compliance.
  • Research & Development: Stay up-to-date with the latest advancements in machine learning and healthcare AI, and explore new technologies and methodologies to enhance our solutions.
  • Documentation: Maintain clear and comprehensive documentation of models, data pipelines, and experimental results.

Requirements
  • Education: Bachelor's or Master's degree in Computer Science, Machine Learning, Artificial Intelligence, or a related quantitative field.
  • Experience:
    • 5+ years of experience in Machine Learning Engineering or a similar role.
    • Proven experience with large-scale data preprocessing, LLM/model training, and fine-tuning.
    • Experience with distributed training (PyTorch Distributed, DeepSpeed, Ray, Hugging Face Accelerate).
    • Experience with GPU/TPU optimization, memory management for large language models.
    • Experience working with healthcare data is highly desirable.
  • Technical Skills:
    • Proficiency in Python and relevant ML libraries (e.g., TensorFlow, PyTorch, Scikit-learn, Pandas, NumPy).
    • Strong understanding of various machine learning algorithms,Large Language Models, and deep learning architectures.
    • Experience with cloud platforms (e.g., GCP, AWS) and distributed computing frameworks (e.g., Spark) is a plus.
    • Familiarity with MLOps practices and tools.
  • Soft Skills:
    • Excellent problem-solving and analytical skills.
    • Strong communication and collaboration abilities.
    • Ability to work independently and as part of a team in a fast-paced environment.
  • Work Authorization:
      • Must be a US Citizen, Green Card holder, or currently in the US have valid H1B visa

Benefits
Why Join Us?
Joining C the Signs is not just about building AI; it's about shaping the future of healthcare. If you are a technical leader with an unshakable belief in the power of AI to save lives and the ability to make it happen at scale, this is your opportunity to create a tangible, global impact.
Benefits:
  • Competitive salary and benefits package.
  • Flexible working arrangements (remote or hybrid options available).
  • The opportunity to work on life-changing AI technology that directly impacts patient outcomes.
  • Join a team that combines cutting-edge innovation with a mission to save lives and improve health equity.
  • Continuous learning opportunities with access to the latest tools and advancements in AI and healthcare.

Apply