Senior Instrument Engineer Jobs in Missouri (NOW HIRING)

Work Schedule
First Shift (Days)
Environmental Conditions
Able to lift 40 lbs. without assistance, Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Cleanroom: no hair products, jewelry, makeup, nail polish, perfume, exposed piercings, facial hair etc... allowed, Laboratory Setting, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)
Job Description
Move fast. Think big. Make an impact that can change lives.
At Thermo Fisher Scientific's St. Louis site, we move with urgency because what we do matters. Every day, our teams are helping turn breakthrough science into biologic medicines for patients around the world-and behind every batch, every decision and every challenge we solve is a patient waiting for what we make.
This is a fast-paced, high-energy environment where science, technology and talented people come together to do extraordinary work. Whether you're in manufacturing, quality, engineering, the lab or a support function, you are part of the mission. Your expertise matters. Your ideas matter. Your ability to move quickly, solve problems and deliver matters.
Why This Role Matters
We're looking for an experienced Senior Metrology Technician who thrives on solving complex technical problems, improving equipment reliability, and helping others grow their technical capability.
Reliable instrumentation is critical to safe, compliant, and efficient operations. As a Senior Metrology Technician, your expertise will directly influence equipment performance, manufacturing continuity, regulatory compliance, and the technical capability of the broader team.
In this role, you'll serve as a senior technical expert for instrumentation, calibration, measurement systems, and equipment reliability supporting GMP manufacturing, laboratory, utility, and facility operations. You'll tackle some of our most challenging calibration and troubleshooting work, lead the technical response to equipment failures and investigations, and help shape how we approach calibration and reliability for the long term.
This is an ideal opportunity for an accomplished technician who enjoys being hands-on while also influencing technical standards, mentoring others, and partnering across Engineering, Manufacturing, Facilities, Automation, and Quality.
What You'll Do

• Lead complex calibration, troubleshooting, adjustment, and repair activities.

• Diagnose electrical, pneumatic, instrumentation, process-control, and equipment-interface issues.

• Troubleshoot pressure, temperature, flow, analytical instrumentation, gas detection, control valves, transmitters, and instrument communications.

• Interpret P&IDs, schematics, loop drawings, wiring diagrams, and technical documentation.

• Partner with Engineering, Manufacturing, Facilities, Automation, and Quality to resolve issues.

• Identify calibration risks, equipment trends, and opportunities to improve procedures.

• Mentor Metrology Technician I and II employees on procedures, repairs, and coordinating monthly work.

• Evaluate instrumentation lifecycle, replacement, obsolescence, and standardization needs.

What You'll Bring

• High school diploma or GED required; related Associate degree preferred.

• 5+ years of experience in instrumentation, metrology, calibration, controls, or equivalent military PMEL experience.

• GMP-regulated manufacturing experience preferred.

• Advanced troubleshooting knowledge across electrical, pneumatic, mechanical, and process instrumentation systems.

• Ability to read P&IDs, schematics, loop drawings, and technical documentation.

• Experience mentoring or training technical employees.

• SAP CMMS or comparable system experience preferred.

• Strong communication, documentation, and cross-functional collaboration skills.

• Well-developed organizational skills and ability to manage priorities independently.

This is a hands-on technical leadership role with no direct people-management responsibility.
Compensation & Benefits
We offer competitive compensation and a comprehensive Total Rewards package designed to support your health, wellbeing, financial security and life outside of work. Benefits include medical, dental and vision coverage, retirement and savings programs, paid time off, wellbeing resources, business resource groups, career development opportunities and additional programs to support you and your family.
Compensation will be determined based on factors including experience, skills, education, internal equity, geographic location and other job-related considerations.
Because when you're helping us deliver for patients, we want to help you thrive-at work and beyond.
Equal Employment Opportunity
Join Thermo Fisher Scientific and be part of our ambitious team that strives for excellence in everything we do. We are an equal opportunity employer, committed to fostering an inclusive and diverse workforce. We value the unique perspectives and contributions of all individuals and actively encourage candidates from all backgrounds to apply.
To apply, please visit our career website at http://jobs.thermofisher.com.
Thermo Fisher Scientific Inc. is an EEO/Affirmative Action Employer and provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other legally protected status.
If you require any accommodations during the application process due to a disability, please contact us at 1-855-471-2255*. We are here to support you and ensure that you have an equal opportunity to succeed.
This telephone line is reserved solely for applicants with disabilities requiring accessibility assistance or accommodations. Messages left for other purposes will not receive a response.
Move fast. Think big. Make an impact that can change lives.
At Thermo Fisher Scientific's St. Louis site, we move with urgency because what we do matters. Every day, our teams are helping turn breakthrough science into biologic medicines for patients around the world-and behind every batch, every decision and every challenge we solve is a patient waiting for what we make.
This is a fast-paced, high-energy environment where science, technology and talented people come together to do extraordinary work. Whether you're in manufacturing, quality, engineering, the lab or a support function, you are part of the mission. Your expertise matters. Your ideas matter. Your ability to move quickly, solve problems and deliver matters.
Why This Role Matters
We're looking for an experienced Senior Metrology Technician who thrives on solving complex technical problems, improving equipment reliability, and helping others grow their technical capability.
Reliable instrumentation is critical to safe, compliant, and efficient operations. As a Senior Metrology Technician, your expertise will directly influence equipment performance, manufacturing continuity, regulatory compliance, and the technical capability of the broader team.
In this role, you'll serve as a senior technical expert for instrumentation, calibration, measurement systems, and equipment reliability supporting GMP manufacturing, laboratory, utility, and facility operations. You'll tackle some of our most challenging calibration and troubleshooting work, lead the technical response to equipment failures and investigations, and help shape how we approach calibration and reliability for the long term.
This is an ideal opportunity for an accomplished technician who enjoys being hands-on while also influencing technical standards, mentoring others, and partnering across Engineering, Manufacturing, Facilities, Automation, and Quality.
What You'll Do

• Lead complex calibration, troubleshooting, adjustment, and repair activities.
• Diagnose electrical, pneumatic, hydraulic, instrumentation, process-control, and equipment-interface issues.
• Troubleshoot pressure, temperature, flow, level, analytical instrumentation, gas detection, control valves, transmitters, and instrument communications.
• Interpret P&IDs, schematics, loop drawings, wiring diagrams, and technical documentation.
• Provide technical leadership during equipment failures, Root Cause Analysis, and investigations.
• Partner with Engineering, Manufacturing, Facilities, Automation, and Quality to resolve recurring issues.
• Identify calibration risks, equipment trends, and opportunities to improve procedures, reliability, and maintenance strategies.
• Support deviations, CAPAs, change controls, qualifications, and inspections.
• Mentor Metrology Technician II and III employees and share advanced troubleshooting practices.
• Evaluate instrumentation lifecycle, replacement, obsolescence, and standardization needs.

What You'll Bring

• High school diploma or GED required; related Associate degree preferred.
• 5+ years of experience in instrumentation, metrology, calibration, controls, or equivalent military PMEL experience.
• GMP-regulated manufacturing experience preferred.
• Advanced troubleshooting knowledge across electrical, pneumatic, hydraulic, mechanical, and process instrumentation systems.
• Experience with Root Cause Analysis, equipment investigations, or reliability improvement.
• Ability to read P&IDs, schematics, loop drawings, and technical documentation.
• Experience mentoring or training technical employees.
• SAP CMMS or comparable system experience preferred.
• Strong communication, documentation, and cross-functional collaboration skills.

This is a hands-on technical leadership role with no direct people-management responsibility.
Compensation & Benefits
We offer competitive compensation and a comprehensive Total Rewards package designed to support your health, wellbeing, financial security and life outside of work. Benefits include medical, dental and vision coverage, retirement and savings programs, paid time off, wellbeing resources, business resource groups, career development opportunities and additional programs to support you and your family.
Compensation will be determined based on factors including experience, skills, education, internal equity, geographic location and other job-related considerations.
Because when you're helping us deliver for patients, we want to help you thrive-at work and beyond.
Other
Relocation assistance is not provided.
Must be legally authorized to work in the United States now and in the future, without sponsorship.
Must be able to pass a comprehensive background check, which includes a drug screening.