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Senior Full Stack Engineer Jobs in Frederick, MD

They are seeking a Senior Full Stack Developer to work with clients across the federal space, including the NIH, focusing on designing and building a cloud-native solution for data analysis and ...

Axle is hiring a Senior Full Stack Developer to work with a number of different clients across the federal space, including the National Center for Advancing Translational Sciences (NCATS) within the ...

Senior Full Stack Developer

Rockville, MD ยท On-site

$120K - $145K/yr

Axle is hiring a Senior Full Stack Developer to work with a number of different clients across the federal space, including the National Center for Advancing Translational Sciences (NCATS) within the ...

Senior Full Stack Developer

Rockville, MD ยท On-site

$120K - $145K/yr

Axle is hiring a Senior Full Stack Developer to work with a number of different clients across the federal space, including the National Center for Advancing Translational Sciences (NCATS) within the ...

DevSecOps Engineer

Rockville, MD ยท On-site

$90/hr

Senior Full Stack Software Engineer -DevSecOps Salary- Up to $135,000/annually OR $90/hr on 1099/C2C Criteria- Need US citizenshipbecause of federal regulations and the sensitive nature of the work ...

Senior Full Stack Software Engineer - DevSecOps Salary- Up to $135,000/annually OR $90/hr on 1099/C2C Criteria- Need US citizenship because of federal regulations and the sensitive nature of the work ...

DevSecOps Engineer

Rockville, MD ยท On-site

$135K/yr

Senior Full Stack Software Engineer - DevSecOps Salary- Up to $135,000/annually OR $90/hr on 1099/C2C Criteria- Need US citizenship because of federal regulations and the sensitive nature of the work ...

Be Seen First

POSITION SUMMARY The Senior Full-Stack Software Engineer & Platform Lead will be responsible for designing, developing, testing, deploying, securing, documenting, and maintaining the KINTEK Business ...

New

Be Seen First

POSITION SUMMARY The Senior Full-Stack Software Engineer & Platform Lead will be responsible for designing, developing, testing, deploying, securing, documenting, and maintaining the KINTEK Business ...

New

Cornerstone Chapel /Specification Full-Stack Developer Job Summary The Full-Stack Developer will specialize in the Rock RMS platform to lead the technical management and customization of the church ...

Cornerstone Chapel /Specification Full-Stack Developer Job Summary The Full-Stack Developer will specialize in the Rock RMS platform to lead the technical management and customization of the church ...

Java Full Stack Developer

Rockville, MD ยท On-site

$53.50 - $69/hr

The Java Full Stack Developer will collaborate with developers, architects, DevOps engineers, Product Owners, Scrum teams, business stakeholders, and Federal partners to deliver secure, scalable, and ...

You will be working with a diverse team of full-stack developers, cloud engineers, and subject matter experts to design and build NCATS Notebooks Hub, a cloud-native solution for managing and ...

New

Full Stack Developer II

Rockville, MD ยท On-site

$107K - $125K/yr

LCG is seeking a Full Stack Developer II to design, develop, test, and maintain enterprise Java-based applications supporting federal clients. The developer will work closely with project managers ...

Full Stack Developer

Leesburg, VA ยท Remote

$115K - $165K/yr

The Full Stack Developer will be responsible for the design, development, integration, testing, deployment, and maintenance of enterprise applications and services. * Design, develop, test, and ...

Full Stack Developer

Leesburg, VA ยท On-site +1

$115K - $165K/yr

The Full Stack Developer will be responsible for the design, development, integration, testing, deployment, and maintenance of enterprise applications and services. * Design, develop, test, and ...

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Senior Full Stack Engineer information

See Frederick, MD salary details

$44.2K

$134K

$189.4K

How much do senior full stack engineer jobs pay per year?

As of Aug 24, 2026, the average yearly pay for senior full stack engineer in Frederick, MD is $133,998.00, according to ZipRecruiter salary data. Most workers in this role earn between $110,400.00 and $157,100.00 per year, depending on experience, location, and employer.

What is a senior full stack engineer?

Senior Full Stack Engineers are experienced software developers who are proficient in both front-end and back-end technologies. They design, build, and maintain complex web applications, overseeing the entire software development process from user interface to server-side logic and databases. In addition to coding, they often mentor junior developers, lead technical decisions, and ensure best practices are followed throughout the project lifecycle. Their broad skill set allows them to bridge the gap between different development teams and deliver cohesive, high-quality solutions.

How do senior full stack engineers balance hands-on coding with mentoring and leading team projects?

Senior Full Stack Engineers often split their time between developing complex features, reviewing code, and guiding junior team members. Alongside hands-on coding, they play a key role in architectural decisions, ensuring code quality, and fostering best practices across the team. Effective communication and delegation skills are crucial, as they frequently collaborate with product managers, designers, and other engineers to align technical solutions with business goals. This balance provides opportunities for leadership growth while keeping technical skills sharp.

What are the key skills and qualifications needed to thrive as a senior full stack engineer, and why are they important?

To thrive as a Senior Full Stack Engineer, you need deep proficiency in front-end and back-end development, strong problem-solving skills, and a solid foundation in computer science, often supported by a relevant degree or equivalent experience. Familiarity with frameworks like React or Angular, back-end technologies such as Node.js or Java, cloud services, and version control systems like Git is typically required, along with experience in CI/CD and testing tools. Excellent communication, leadership, and collaboration skills help you guide teams and coordinate across disciplines. These skills are crucial for delivering scalable, high-quality software solutions and effectively leading complex projects.

What is the difference between Senior Full Stack Engineer vs Software Developer?

AspectSenior Full Stack EngineerSoftware Developer
CredentialsBachelor's degree in CS or related field; experience often requiredBachelor's degree in CS or related field; entry-level to mid-level experience
Work EnvironmentCollaborates across front-end and back-end teams, often in agile settingsFocuses on coding, testing, and debugging software applications
Industry UsageCommon in tech companies, startups, and enterprise software firmsWidely used across various industries for software development roles

While both roles involve coding and software development, a Senior Full Stack Engineer typically has broader responsibilities across both front-end and back-end systems, often with more experience and leadership duties compared to a Software Developer, who may focus on specific parts of the software stack.

How much do senior full stack engineers make?

Senior full stack engineers typically earn between $100,000 and $160,000 annually, depending on experience, location, and company size. They often possess skills in multiple programming languages, frameworks, and tools, and may receive additional compensation such as bonuses or stock options.

What does a senior full stack engineer do?

A senior full stack engineer designs, develops, and maintains both the front-end and back-end components of web applications. They often lead technical projects, write clean code, and use tools like JavaScript, Python, or Java, along with frameworks such as React or Node.js. They also troubleshoot issues, optimize performance, and collaborate with cross-functional teams to deliver complete software solutions.

What are the most commonly searched types of Full Stack Engineer jobs in Frederick, MD?

The most popular types of Full Stack Engineer jobs in Frederick, MD are:

What cities near Frederick, MD are hiring for Senior Full Stack Engineer jobs?

Cities near Frederick, MD with the most Senior Full Stack Engineer job openings:

Infographic showing various Senior Full Stack Engineer job openings in Frederick, MD as of August 2026, with employment types broken down into 85% Full Time, 10% Part Time, and 5% Contract. Highlights an 86% Physical, 5% Hybrid, and 9% Remote job distribution, with an average salary of $133,998 per year, or $64.4 per hour.

Senior Full Stack Developer

Axle

Rockville, MD โ€ข On-site

Full-time

Re-posted 28 days ago


Job description

Job Summary:
Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. They are seeking a Senior Full Stack Developer to work with clients across the federal space, including the NIH, focusing on designing and building a cloud-native solution for data analysis and exploration.
Responsibilities:
โ€ข Build scalable, reliable, and flexible applications in TypeScript using NodeJS and Angular 9+
โ€ข Design, implement, and/or use RESTful web services
โ€ข Implement modern and responsive UI for the web and variety of devices
โ€ข Participate in agile software development, prototyping, testing, and code reviews with a small team of developers
โ€ข Write robust unit and end-to-end tests
Qualifications:
Required:
โ€ข Bachelorโ€™s Degree in Computer Science, Data Science, Bioinformatics or other related field (years of work experience will be considered in lieu of degree)
โ€ข 3+ years experience working with TypeScript/JavaScript
โ€ข 3+ years experience as a full-stack developer
โ€ข Experience with Jupyter notebooks and open-source application and dashboard projects (i.e., Shiny, Streamlit, Solara, etc...)
โ€ข Experience with the following: Node.js, Angular 19+, NoSQL databases (MongoDB), Containers and container orchestration tools (Docker, Kubernetes), DevOps tools (Jenkins, GitHub Actions)
โ€ข Familiarity with VCS such as Git
โ€ข Experience with unit and end-to-end testing frameworks
โ€ข Experience with using and leveraging GenAI technologies (i.e., CursorAI, Cline, Windsurf)
โ€ข Critical thinking, problem solving, and attention to detail
โ€ข Clear, concise communication
โ€ข Technical writing ability
โ€ข Familiarity working in an Agile environment
โ€ข Attention to detail when building visually appealing and intuitive UI
Company:
At Axle, we are driven by the mission to accelerate discovery and enhance organizational outcomes by revolutionizing operations with our innovative solutions. Founded in 2002, the company is headquartered in Rockville, USA, with a team of 501-1000 employees. The company is currently Late Stage.