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Senior Fastapi Developer Jobs in Boston, MA (NOW HIRING)

Languages & Frameworks : Python, JavaScript, Django / DRF, FastAPI, Vue * Platform : EKS ... Senior Software Engineer to join our Integrations team. You will design, build, and maintain ...

New

Senior Software Engineer, Backend

Boston, MA · On-site +1

$127K - $195K/yr

Languages & Frameworks : Python, JavaScript, Django / DRF, FastAPI, Vue * Platform : EKS ... Senior Software Engineer to join our Integrations team. You will design, build, and maintain ...

New

Senior Software Engineer

Boston, MA · On-site

$133K - $175K/yr

Backend expertise with modern frameworks such as Django, FastAPI, or Node.js, along with strong SQL ... Bonus experience with distributed systems, ETL/data pipelines, DevOps tooling (Kubernetes, Helm ...

Senior AI Engineer - Customer Agent

Boston, MA · On-site

$113K - $155K/yr

They are seeking a Senior AI Engineer on the Customer Agent team to design and build scalable ... FastAPI, Django preferred). • Experience creating human and automated evals to ensure high AI ...

Senior Frontend Engineer

Natick, MA

$126K - $174K/yr

... Python based backend services such as FastAPI • Experience improving performance and ... percent DevOps and testing tools Daily Responsibilities • 60 percent Hands on Development ...

Senior Full Stack Software Engineer

Boston, MA · On-site +1

$160K - $210K/yr

About the Role A growing technology startup is hiring a Senior Full Stack Software Engineer to help ... Backend: Node.js (Express or NestJS) and/or Python (Django or FastAPI) * Databases: PostgreSQL ...

Senior Software Engineer

Boston, MA · On-site

$133K - $175K/yr

T. is partnering with Via to find a Senior Software Engineer. See details below: About the Role: An ... Developing RESTful APIs (using frameworks such as FastAPI) secured by OAuth2/Auth * Integrating ...

Senior Software Engineer

Boston, MA · On-site

$133K - $175K/yr

T. is partnering with Via to find a Senior Software Engineer. See details below: About the Role: An ... Developing RESTful APIs (using frameworks such as FastAPI) secured by OAuth2/Auth * Integrating ...

Senior Software Engineer

Boston, MA · On-site

$133K - $175K/yr

T. is partnering with Via to find a Senior Software Engineer. See details below: About the Role: An ... Developing RESTful APIs (using frameworks such as FastAPI) secured by OAuth2/Auth * Integrating ...

Senior AI Engineer

Boston, MA · On-site

$113K - $155K/yr

They are seeking a Senior AI Engineer to design, build, and scale production-grade LLM integrations ... FastAPI, Flask, or Django) and TypeScript or JavaScript, with experience in modern frontend ...

Senior AI Engineer

Cambridge, MA · On-site

$114K - $156K/yr

Design, build, and deliver backend services and application components using Python/FastAPI ... DevOps, and Reliability: Build and maintain CI/CD pipelines, infrastructure-as-code, automated ...

Senior AI Engineer

Cambridge, MA · On-site

$114K - $156K/yr

Design, build, and deliver backend services and application components using Python/FastAPI ... DevOps, and Reliability: * Build and maintain CI/CD pipelines, infrastructure-as-code, automated ...

They are seeking a Senior AI Application Engineer to design, build, and scale production-grade LLM ... FastAPI, Flask, or Django) and TypeScript or JavaScript, with experience in modern frontend ...

Showing results 21-40

Senior Fastapi Developer information

See Boston, MA salary details

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How much do senior fastapi developer jobs pay per hour?

As of Sep 13, 2026, the average hourly pay for senior fastapi developer in Boston, MA is $67.06, according to ZipRecruiter salary data. Most workers in this role earn between $56.92 and $75.19 per hour, depending on experience, location, and employer.

What does a Senior FastAPI Developer do?

A Senior FastAPI Developer designs, develops, and maintains backend web applications using the FastAPI framework in Python. They are responsible for building scalable APIs, optimizing performance, ensuring security best practices, and integrating with databases and external services. Senior developers also mentor junior team members, contribute to architecture decisions, and collaborate closely with front-end engineers and stakeholders to deliver robust software solutions.

What are the key skills and qualifications needed to thrive as a Senior FastAPI Developer?

To thrive as a Senior FastAPI Developer, you need deep expertise in Python, RESTful API design, and experience building scalable web backends, typically supported by a degree in computer science or related field. Familiarity with FastAPI, Docker, cloud platforms (such as AWS or Azure), and CI/CD tools is highly valued, along with proficiency in testing frameworks. Strong problem-solving, leadership, and communication skills help you collaborate effectively with cross-functional teams and mentor junior developers. These skills enable the delivery of robust, efficient, and maintainable APIs that support business goals and high user demands.

What are some common challenges faced by Senior FastAPI Developers when scaling applications, and how can these be addressed?

Senior FastAPI Developers often encounter challenges related to managing high concurrency, optimizing API performance, and ensuring robust security as applications scale. To address these, it’s important to implement asynchronous programming practices, leverage efficient database queries, and utilize API gateways for better traffic management. Collaboration with DevOps and QA teams is also essential to automate deployments and monitor system health, ensuring smooth scaling and reliable user experiences.

What are the most commonly searched types of Fastapi Developer jobs in Boston, MA?

The most popular types of Fastapi Developer jobs in Boston, MA are:

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For Senior Fastapi Developer jobs in Boston, MA, the most frequently searched job titles are:

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Cities near Boston, MA with the most Senior Fastapi Developer job openings:

Senior Software Engineer, Backend

Boston, MA • On-site

PathAI
Software Development • 51 - 200 employees

$127K - $195K/yr

Full-time

Posted 2 days ago

New


Job description

PathAI's mission is to improve patient outcomes with AI-powered pathology. 

Our platform promises substantial improvements to the accuracy of diagnosis and the efficacy of treatment of diseases like cancer, leveraging modern approaches in machine learning and artificial intelligence. We have a track record of success in deploying AI algorithms for histopathology in translational research, pathology labs and clinical trials.  Rigorous science and careful analysis is critical to the success of everything we do. Our team, composed of diverse employees with a wide range of backgrounds and experiences, is passionate about solving challenging problems and making a huge impact on patient outcomes.

At PathAI, we are constantly evaluating our tech stack and our current tools consist of:

  • Languages & Frameworks: Python, JavaScript, Django / DRF, FastAPI, Vue
  • Platform: EKS (Kubernetes), S3, RDS / PostgreSQL, SQS, MSK (Kafka)
  • Tooling: GitLab CI/CD, Terraform, Docker, Datadog
The Opportunity

We're looking for a backend focused Senior Software Engineer to join our Integrations team. You will design, build, and maintain critical APIs and data pipelines that enable seamless clinical workflows and real-time data exchange across external systems and our core product.

  • You will drive the architecture of our application platform, considering the team and our future product roadmap.
  • You will collaborate with product, design, machine learning, and infrastructure teams.
  • You will drive and uphold high engineering standards, bringing consistency to the codebases you encounter and ensuring software is adequately reviewed, tested, and integrated.
  • You will foster a culture of continuous learning by mentoring teammates and sharing technical knowledge.
  • You will champion code quality for both your individual contributions and the broader team's output.
  • You will contribute to a SaaS platform used ensuring reliability, data integrity, and compliance with industry standards.
  • You will collaborate with clinical, QA, and regulatory teams to ensure software changes meet validation expectations and support inspection readiness.
Who You Are:
(Required)
  • You have a BS in Computer Science, Software Engineering or closely related technical field.
  • You have 5+ years of full life cycle development experience.
  • You have demonstrated the ability to take on complex tasks, learn quickly and work in a proactive manner.
  • You have demonstrated experience and skills in designing and building Python-based (FastAPI or Django) applications.
  • You have a demonstrated foundation in data structures, algorithms, and OO design.
  • You have a demonstrated ability to collaborate with a distributed team and to work autonomously on projects; You have demonstrated problem-solving skills and the ability to work in a fast-paced, agile environment.
  • You have strong interpersonal and communication skills, with the ability to attend client-facing meetings and explain technical concepts to non-experts.
  • You have demonstrated cloud platform experience (AWS) 

Preferred:

  • You have an advanced degree in Computer Science, Software Engineering or closely related technical field
  • You have experience working in the healthtech industry, including working with HL7, HL7 FHIR, or DICOM
  • You have experience with modern frontend JavaScript frameworks such as React, Vue, or equivalent for building responsive, user-friendly interfaces.
  • You have hands-on experience with CI/CD tools, e.g. GitLab CI
  • You have demonstrated knowledge of containerization technologies like Docker and container orchestration tools like Kubernetes
  • You have knowledge of some IaC framework
  • You have experience deploying and monitoring VPNs
  • You have excellent organizational skills and the ability to prioritize and manage multiple projects efficiently.

This is a hybrid position based in Boston, MA.
Relocation benefits are not available for this position.

The expected salary range for this position based on the primary location Boston, MA is $127,500 - $195,500.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  

PathAI is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.