POSITION SUMMARY
TheCenter for Computational Biology(CCB)is seeking an experienced senior software engineer to join a growing team of developers within CCB and the other centers across the Flatiron Institute who help build andmaintainHumanBase.HumanBaseis a dynamic and interactive web-based platform that supports thousands of biomedical researchers in exploring the molecular mechanisms of human disease. This position is ideal for an experienced engineer with bioinformatics experience who thrives on solving complex problems at the intersection of large-scale data, pipeline building, advanced analytics, and scientific discovery. This is a high-impact role that directly advances the study of human genomics and disease.
The successful candidate will collaborate closely with researchers at the Center for Computational Biology to translatecutting-edgecomputational biology research into scalable production systems and data pipelines that powerHumanBase. This is a hands-onbackendrole for an experienced engineer withexpertisein biological data, genomics, and -omics technologies. They will also have experience processing large-scale -omics datasets,maintainingproduction software systems,designingandoptimizingdata-intensive pipelines, and supporting machine learning workflows in scientific computing environments.
This is a full-time position based in the Simons Foundation offices in New York City. Visit the Simons Foundationcareer pageto learn more.
ESSENTIAL FUNCTIONS/RESPONSIBILITIES
Design, develop, andoptimizescalable genomics and biomedical data processing pipelines that ingest, normalize, and transform heterogeneous datasets
Apply software engineering best practices, including code review, testing, version control, documentation, CI/CD, and deployment automation
Experience working with large, heterogeneous biological datasets in Python (HDF5, Parquet,PyArrow,xarray) -ideally in genomics or biomedical contexts
Experience building andoperatingdistributed compute workflows and orchestration systems (e.g., Celery,Dask, SLURM,Nextflow,Snakemake) for large-scale genomic or biomedical data processing
Demonstrated experience with the full software development lifecycle (SDLC), including testing, CI/CD, version control, and deployment
Background working in computational biology, bioinformatics, or a related field, with experience developing software that supports biological research
Related Skills & Other Requirements
Expertisein bioinformatics, including experience with genomic data processing, analysis pipelines, and related computational methods.
REQUIRED APPLICATION MATERIALS
COMPENSATION AND BENEFITS
Our Commitment to Expanding Pathways to Science & Opportunities for All:
Many of the greatest ideas and discoveries come from a diverse mix of minds, backgrounds, and experiences. The Simons Foundation is committed to advancing basic science and mathematics to benefit humankind and expand our collective understanding of our world. As part of our mission, we support partners, programs, and initiatives that seek to broaden the scientific community and open pathways toscienceand mathematicscareers.
The Simons Foundation provides equal opportunities to all applicants without regard to race, religion, color, age, sex, pregnancy, national origin, sexual orientation, gender identity, genetic disposition, neurodiversity, disability, veteran status, or any other protected category under federal, state, and local law.