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Senior Computational Biologist Jobs (NOW HIRING)

MSD

Senior Computational Biologist (Hybrid)

Rahway, NJ · Hybrid

The Omics Platforms team within Digital Insights group, is seeking applicants for a Senior Computational Biologist with a strong background in proteomics and multi-omics data integration to join our ...

Tempus

Senior Computational Biologist I

Chicago, IL

$115K - $175K/yr

Computational Biology, Genetics, or similar). Alternatively, a PhD in computational biology with a strong record of multi-omic, high-throughput sequencing data analysis * Computational skills using R ...

Tempus

Senior Computational Biologist I

New York, NY · On-site

$115K - $175K/yr

Computational Biology, Genetics, or similar). Alternatively, a PhD in computational biology with a strong record of multi-omic, high-throughput sequencing data analysis * Computational skills using R ...

Valo Health

Staff Computational Biologist

Lexington, MA · Hybrid

As a senior member of the Translational Platform Engineering team, you will act as a product owner ... The Staff Computational Biologist is the key to translating use cases into technical specifications ...

Valo Health

Staff Computational Biologist

Lexington, MA · On-site +1

$195K - $230K/yr

As a senior member of the Translational Platform Engineering team, you will act as a product owner ... The Staff Computational Biologist is the key to translating use cases into technical specifications ...

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How much do senior computational biologist jobs pay per year?

As of Jun 25, 2026, the average yearly pay for senior computational biologist in the United States is $93,988.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,500.00 and $117,000.00 per year, depending on experience, location, and employer.

What is a Senior Computational Biologist job?

A Senior Computational Biologist applies advanced computational and analytical techniques to interpret biological data, often in fields like genomics, systems biology, or drug discovery. They develop algorithms, analyze large datasets, and integrate biological and computational expertise to extract meaningful insights. This role typically involves working closely with biologists, bioinformaticians, and software engineers to develop new models and tools. Senior professionals in this field also contribute to project leadership, research strategy, and mentoring junior scientists.

What are some typical projects or responsibilities for a Senior Computational Biologist in a research or industry setting?

Senior Computational Biologists often lead the design and execution of data-driven research projects, such as analyzing large-scale genomic, transcriptomic, or proteomic datasets to uncover biological patterns and insights. They may develop and maintain computational pipelines, collaborate closely with wet-lab scientists to integrate experimental data, and contribute to scientific publications or regulatory submissions. In addition, they frequently mentor junior team members, coordinate with cross-functional departments, and help shape data analysis strategies for ongoing and future research initiatives. This multifaceted role requires balancing technical work with communication and leadership to support scientific goals and innovation within the organization.

What are the key skills and qualifications needed to thrive in the Senior Computational Biologist position, and why are they important?

To thrive as a Senior Computational Biologist, you need advanced expertise in bioinformatics, statistical analysis, genomics, and computational modeling, often supported by a PhD or equivalent experience in computational biology or a related field. Familiarity with programming languages such as Python or R, experience with next-generation sequencing data, and proficiency in using bioinformatics pipelines and cloud computing platforms are typically expected. Strong communication, problem-solving abilities, and project management skills help facilitate collaboration and leadership within interdisciplinary research teams. These competencies are crucial for driving innovative biological discoveries, ensuring data integrity, and translating complex datasets into actionable scientific insights.

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Senior Computational Biologist jobs near you
Sr Computational Biologist

Sr Computational Biologist

Foundation Medicine

Boston, MA

$145K - $180K/yr

Full-time

Posted 17 days ago

Job description

About the Job

The Sr Computational Biologist position sits within the Computational Discovery team and is responsible for building advanced algorithms and technical features that will drive R&D's innovation roadmap. This role leverages multi-modal data, including large scale genomics, real-world clinical outcomes, and imaging datasets, to identify and establish feasibility of novel biomarkers and therapeutic targets. The Sr Computational Biologist contributes as a subject matter expert in cross-functional initiatives to identify opportunities for growth and innovation that can advance FMI's assay and data product capabilities. This position requires a deep understanding of cancer biology and bioinformatics, as well as the ability to communicate complex findings to internal and external stakeholders. 

Key Responsibilities

  • Utilize statistical expertise to explore multimodal data and lead scientific investigations into mechanisms of oncogenesis, prognostic and predictive biomarkers, drug resistance, and disease monitoring.
  • Manage and/or support code bases/repositories and dataset versioning and quality control.
  • Represent Computational Discovery to cross-functional departments and leadership teams to refine product strategy.
  • Collaborate with clinical partners in translational research projects that result in abstracts and publications.
  • Communicate results to both technical and non-technical stakeholders.
  • Other duties as assigned.

Qualifications:

Basic Qualifications:

  • PhD in a life science or mathematical field with a clinical focus and 4+ years of industry or post-doctorate experience within Cancer Biology, Bioinformatics, Biochemistry, or another related life science; OR Master's degree in a life science or mathematical field with clinical focus and 6+ years of industry experience within Cancer Biology, Bioinformatics, Biochemistry, or another related field
  • Proficiency with one or more of the following scientific computing languages: Python, R, Matlab, or Java

Preferred Qualifications:

  • Practical graduate and post-doctoral experience exhibited by first-author publications
  • Subject matter expertise in one of the following areas: cancer genomics, bioinformatics, biostatistics, or machine learning
  • Working knowledge of NGS technology, biomarker development, and real-world clinical outcomes
  • Working knowledge of clinical nomenclature including line of therapy, stage, ECOG, and the patient journey in oncology
  • Experience with computational technologies such as databases (SQL), cloud computing (AWS), and deep learning (AI)
  • Experience managing collaborations with multiple stakeholders
  • Experience mentoring and developing junior scientists
  • Translational research experience and ability to analyze and critically interpret scientific literature
  • Understanding of HIPAA and the importance of patient data privacy
  • Commitment to reflect FMI's values: Integrity, Courage, and Passion 

The expected salary range for this position based on the primary location of Boston, MA is $145,000 - $180,000 per year. The salary range is commensurate with FMI's compensation practice and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for FMI benefits.

#LI-Onsite

Foundation Medicine, Inc. (FMI) is a global, patient-focused precision medicine company delivering high-quality, transformative diagnostic solutions in cancer and other diseases.

Foundation Medicine is proud to be an Equal Opportunity and Affirmative Action employer and considers all qualified applicants for employment without regard to race, color, religion, sex, gender, sexual orientation, gender identity, ancestry, age, or national origin.  Further, qualified applicants will not be discriminated against on the basis of disability or protected veteran status.  We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.  See also FMI's EEO Statement and EEO is the Law and Supplement.  If you have a disability or special need that requires accommodation, please let us know by completing this form.  (EOE/AAP Employer)

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