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Senior Backend Python Jobs in Denver, CO (NOW HIRING)

Sr AI Engineer

Lone Tree, CO · On-site +1

$103K - $141K/yr

This role focuses on building scalable, secure backend AI services, reusable AI capabilities, and ... Languages: C#, Python, Node.js (JavaScript/TypeScript), RESTful APIs * AI: Azure AI Foundry ...

Senior Software Engineer II

Denver, CO · On-site

$150 - $190/hr

Strong command of at least one backend language (Ruby, Go, Python, or similar) * Track record of leading technical design * Active AI fluency using tools like GitHub Copilot, Cursor, or LLM-based ...

Work with various teams to integrate backend systems with current and future product offerings ... Competency in other coding languages such as Javascript, PHP, Python, Java, RoR, etc * In-depth ...

Senior Software Engineer

Denver, CO · On-site +1

$126K - $166K/yr

The Senior Software Engineer designs, builds, and maintains the technical systems and application ... Proficiency in one or more back-end languages (e.g., Python, Javascript, TypeScript) and ...

Senior Software Engineer

Denver, CO · On-site +1

$126K - $166K/yr

The Senior Software Engineer designs, builds, and maintains the technical systems and application ... Proficiency in one or more back-end languages (e.g., Python, Javascript, TypeScript) and ...

Work with various teams to integrate backend systems with current and future product offerings ... Competency in other coding languages such as Javascript, PHP, Python, Java, RoR, etc * In-depth ...

The Role As a Senior Software Engineer, you'll have real ownership over the software and systems ... Backend: Django, Python * Frontend: React, TypeScript, GraphQL * Infrastructure: AWS * Other Tools ...

Senior Applied ML Engineer

Denver, CO · Remote

$125K - $183K/yr

Build scalable ML pipelines and backend services that integrate into production-grade agents and ... Strong proficiency in Python and ML frameworks (PyTorch, TensorFlow, Hugging Face). * Experience ...

Showing results 21-40

Senior Backend Python information

See Denver, CO salary details

$16.5K

$152.6K

$196.6K

How much do senior backend python jobs pay per year?

As of Aug 19, 2026, the average yearly pay for senior backend python in Denver, CO is $152,573.00, according to ZipRecruiter salary data. Most workers in this role earn between $149,800.00 and $172,400.00 per year, depending on experience, location, and employer.

What does a senior backend Python developer do?

A Senior Backend Python Developer designs, builds, and maintains the server-side logic of web applications using Python. They are responsible for creating robust APIs, optimizing databases, ensuring application security, and integrating third-party services. In addition, they often mentor junior developers, contribute to architectural decisions, and collaborate closely with frontend and DevOps teams. Their work ensures that applications are scalable, reliable, and efficient. Senior developers typically have several years of experience and deep knowledge of Python frameworks like Django or Flask.

What are the key skills and qualifications needed to thrive as a senior backend Python developer?

To thrive as a Senior Backend Python Developer, you need expertise in Python programming, strong knowledge of backend frameworks (such as Django or Flask), and experience with database management, often backed by a degree in computer science or equivalent experience. Familiarity with version control systems like Git, containerization tools like Docker, cloud platforms (e.g., AWS), and possibly certifications in cloud or Python technologies are common requirements. Outstanding problem-solving skills, effective communication, and the ability to mentor junior developers help set top performers apart. These competencies ensure the development of robust, scalable, and maintainable backend systems that support business objectives.

What are some common challenges senior backend Python developers face when working on large-scale systems?

Senior Backend Python developers working on large-scale systems often encounter challenges such as ensuring application scalability, maintaining code quality across distributed teams, and optimizing performance for high traffic. Balancing the integration of new features with legacy system constraints can also be demanding. Effective communication and collaboration with frontend teams, DevOps, and product managers are crucial for delivering reliable and maintainable backend solutions.

What is the difference between Senior Backend Python vs Backend Developer?

AspectSenior Backend PythonBackend Developer
Required CredentialsBachelor's in CS or related, 5+ years experience, Python expertiseBachelor's in CS or related, 2-4 years experience, Python knowledge
Work EnvironmentTech companies, startups, enterprise systemsTech firms, startups, software agencies
Employer & Industry UsageUsed across industries requiring scalable backend solutionsCommon in web development and software services
Search & Comparison IntentUnderstanding senior roles, responsibilities, salaryEntry to mid-level backend roles, skill requirements

Senior Backend Python professionals typically have more experience, advanced skills, and leadership responsibilities compared to Backend Developers. They often work on complex systems, mentor junior staff, and have a broader understanding of architecture. Backend Developers focus on building and maintaining backend services with less emphasis on leadership or strategic planning.

Sr. Back-end Ground Software Engineer - Lunar Permanence

Blue Origin, LLC

Denver, CO • On-site

$181K - $254K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 27 days ago


Blue Origin rating

8.7

Company rating: 8.7 out of 10

Based on 91 frontline employees who took The Breakroom Quiz

17th of 72 rated aerospace companies


Job description

Application close date:
Applications will be accepted on an ongoing basis until the requisition is closed.
At Blue Origin, we envision millions of people living and working in space for the benefit of Earth. We're working to develop reusable, safe, and low-cost space vehicles and systems within a culture of safety, collaboration, and inclusion. Join our team of problem solvers as we add new chapters to the history of spaceflight!
This role is part of the Lunar Permanence business unit, which develops Blue Origin's Blue Moon landers and related products. To further Blue Origin's mission of millions of people living and working in space for the benefit of Earth, we are building sustainable infrastructure for our transport of crew and cargo from Earth to the lunar surface.
As a Ground Software Engineer in Blue Origin's Lunar Permanence program, you will help build, test, and integrate the software required for the Lunar Permanence Mission Operations Centers used to fly lunar space vehicles. You will work closely with space vehicle and ground subsystem teams. You will be responsible for developing, testing, and deploying software that will enable Earth-based operators to perform mission-critical functions supporting Blue Origin operations, including flight/ground system integration and testing, mission activity planning, telemetry data processing and display, spacecraft system/health monitoring and fault detection, and operations training.
We are looking for someone to apply their technical expertise and dedication to quality to positively impact safe human spaceflight. Passion for our mission is required!
Responsibilities:
  • Design, implement, test, verify and deploy mission operations, safety-critical software systems, ensuring the success of the overall Ground System (hardware/software) supporting space flight operations.
  • Collaborate with multidisciplinary teams, including engineers representing space vehicle systems, mission-control infrastructure, operations fields, and other customers to define software requirements, architectures, and designs.
  • Develop rapid prototypes to prove out concepts and quantify technical risks.
  • Coordinate with mission control infrastructure and mission system engineers to plan, develop, and lead system verification and qualification, to ensure software products that meet system requirements and safety-critical standards.
  • Produce and contribute to documentation for software architecture, design, verification plans, user manuals and training material.
  • Follow software development processes that meet Blue Origin and customer-required standards to ensure software safety and reliability.
  • Support frequent update cycles for pre-flight testing, mission validation exercises and events related to operations training.
  • Support mission control software operations responsibilities (maintenance, problem correction, improvements) during operator training; ground data system verification, validation, and certification; spacecraft integration; and flight.
  • Integrate software components, build, and run unit-level and system-level tests, validate using Software-in-the-Loop and Hardware-in-the-Loop simulators, and release certified code.

Qualifications:
  • B.S. or higher degree in Software or Engineering related field.
  • 8+ years of software development experience.
  • Proven software development in Python and/or Rust.
  • A willingness to work and integrate with frontend developers and React-based frameworks.
  • Experience in full lifecycle software engineering. Including: system design, software implementation and verification, system integration, and release.
  • Skills in software build automation, continuous integration, configuration management, verification, and deployment.
  • Experience in designing and implementing scalable software architectures.
  • Familiarity with Linux environment and basic Unix system administration activities.
  • Excellent verbal and written communication skills.
  • Ability to work collaboratively in cross-functional teams.
  • Passion for spaceflight and space exploration.

Desired:
  • 5+ years of proven ability in developing software supporting systems in critical applications (e.g. aviation, spaceflight, nuclear power, business-critical web services, etc.).
  • Experience crafting and developing software for aerospace operations.
  • Familiar with infrastructure-as-code, services-as-code, and cloud technologies.
  • Understanding of space-based communications protocols, such as CCSDS.
  • Familiarity with cybersecurity practices to ensure the safety of software systems.
  • Compliance experience with NPR 7150.2x.
  • Experience with fault-tolerant software design, human error assessment, and human error prevention and fault tolerance.
  • Experience with spacecraft subsystems and associated software.

Base Pay Range for:
CO applicants is $181,626.00 - $254,275.35WA applicants is $197,529.00 - $276,539.55
Other site ranges may differ
Culture Statement
Don't meet all desired requirements? Studies have shown that some people are less likely to apply to jobs unless they meet every single desired qualification. At Blue Origin, we are dedicated to building an authentic workplace, so if you're excited about this role but your past experience doesn't align perfectly with every desired qualification in the job description, we encourage you to apply anyway. You may be just the right candidate for this or other roles.
Export Control Regulations
Applicants for employment at Blue Origin must be a U.S. citizen or national, U.S. permanent resident (i.e. current Green Card holder), or lawfully admitted into the U.S. as a refugee or granted asylum.
Background Check
  • Required for all positions: Blue's Standard Background Check
  • Required for Certain Job Profiles: Defense Biometric Identification System (DBIDS) background check if at any time the role requires one to be on a military installation
  • Required for Certain Job Profiles: Drivers who operate Commercial Motor Vehicles with a Gross Vehicle Weight (GVW), Gross Vehicle Weight Rating (GVWR) or combination of power unit and trailer that meets or exceeds 10,001 lbs. and/or transports placardable amounts of hazardous materials by ground in any vehicle on a public road while in commerce, may be subject to additional Federal Motor Carrier Safety Regulations including: Driver Qualification Files, Medical Certification (obtained before onboarding), Road Test, Hours of Service, Drug and Alcohol Testing, vehicle inspection requirements, CDL requirements (if applicable) and hazardous materials transportation/shipping training.
  • Required for certain Job Profiles: Ability to obtain and maintain Merchant Mariner Credential, which includes pre-employment and random drug testing as well as DOT physical

Benefits
  • Benefits include: Medical, dental, vision, basic and supplemental life insurance, paid parental leave, short and long-term disability, 401(k) with a company match of up to 5%, and an Education Support Program.
  • Stock Options for all regular employees (working at least 20 hours/week)
  • Paid Time Off: Up to four (4) weeks per year based on weekly scheduled hours, and up to 14 company-paid holidays.
  • Dependent on role type and job level, employees may be eligible for benefits and bonuses based on the company's intent to reward individual contributions and enable them to share in the company's results, or other factors at the company's sole discretion. Bonus amounts and eligibility are not guaranteed and subject to change and cancellation. Please check with your recruiter for more details.

Equal Employment Opportunity
Blue Origin is proud to be an Equal Opportunity/Affirmative Action Employer and is committed to attracting, retaining, and developing a highly qualified and dedicated work force. Blue Origin hires and promotes people on the basis of their qualifications, performance, and abilities. We support the establishment and maintenance of a workplace that fosters trust, equality, and teamwork. We provide all qualified applicants for employment and employees with equal opportunities for hire, promotion, and other terms and conditions of employment, regardless of their race, color, religion, sex, sexual orientation, gender identity, national origin/ethnicity, age, physical or mental disability, genetic factors, military/veteran status, or any other status or characteristic protected by federal, state, and/or local law. Blue Origin will consider for employment qualified applicants with criminal histories in a manner consistent with applicable federal, state, and local laws, including the Washington Fair Chance Act, the California Fair Chance Act, the Los Angeles Fair Chance in Hiring Ordinance, and other applicable laws. For more information on "Know Your Rights," please see here.
Affirmative Action and Disability Accommodation
Applicants wishing to receive information on Blue Origin's Affirmative Action Plans, or applicants requiring a reasonable accommodation in order to participate in the application and/or interview process, please contact us at EEOCompliance@blueorigin.com. Please note this is a publicly managed inbox. Please do not include any personal medical information in your request.

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Blue Origin logo

About Blue Origin

Sourced by ZipRecruiter

Blue Origin is a private aerospace manufacturing and suborbital spaceflight services company based in Kent, Washington, USA. Established in 2000 by Amazon founder Jeff Bezos, the company operates in the cutting-edge aerospace industry aiming to build a future where millions of people can live and work in space. They develop a variety of technologies, with a focus on reusable rocket systems which significantly reduce the cost of space travel. Blue Origin's core mission is to make this vision come to life by incrementally building on its successes with an ultimate vision of dramatic cost reduction and increased reliance on reusable spacecraft.

Industry

Space research administration

Company size

1,001 - 5,000 Employees

Headquarters location

Kent, WA, US

Year founded

2000