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Senior Backend Python Jobs in Minnesota (NOW HIRING)

Senior Platform Engineer

Eagan, MN · On-site

$106K - $146K/yr

As a Senior Platform Engineer , you will design and deliver backend services with growing scope and ... Strong proficiency in Python (FastAPI or similar) or another backend language, with experience in ...

Senior Software Engineer

Minneapolis, MN · On-site +1

$127K - $168K/yr

The Senior Software Engineer designs, builds, and maintains the technical systems and application ... Proficiency in one or more back-end languages (e.g., Python, Javascript, TypeScript) and ...

## Senior Software EngineerApplyremote type: Hybridlocations: Minneapolistime type: Full timeposted on ... NET Core, Python, or Node.js) and API design.* Strong understanding of backend technologies that ...

Senior Software Engineer

Minneapolis, MN · On-site +1

$127K - $168K/yr

The Senior Software Engineer designs, builds, and maintains the technical systems and application ... Proficiency in one or more back-end languages (e.g., Python, Javascript, TypeScript) and ...

Senior Software Engineer

Maple Plain, MN · On-site

$107K - $161K/yr

In this role, you will own complex backend services at the intersection of business logic, data ... Proficiency in Python and/or C# for designing, building, testing, and monitoring production-grade ...

In this role, you will own complex backend services at the intersection of business logic, data ... Proficiency in Python and/or C# for designing, building, testing, and monitoring production-grade ...

Senior Software Engineer

Maple Plain, MN · On-site

$127K - $167K/yr

In this role, you will own complex backend services at the intersection of business logic, data ... Proficiency in Python and/or C# for designing, building, testing, and monitoring production-grade ...

Senior Software Engineer

Minneapolis, MN · On-site

$121K - $151K/yr

The Senior Software Engineer position is responsible produce scalable software solutions for Ryan ... NET Core, Python, or Node.js) and API design. * Strong understanding of backend technologies that ...

Role - Sr/Lead AI/ML Engineer Location: Minnetonka, MN (Onsite/Hybrid) * Must be local to the ... Strong software development skills using Python, Go, TypeScript, or comparable backend languages.

... Python, Redis, Postgres, and Kafka in a microservices architecture. You will work with our product ... You have optimized backend systems for latency, performance, and scalability. Education Bachelor ...

Showing results 21-40

Senior Backend Python information

What does a senior backend Python developer do?

A Senior Backend Python Developer designs, builds, and maintains the server-side logic of web applications using Python. They are responsible for creating robust APIs, optimizing databases, ensuring application security, and integrating third-party services. In addition, they often mentor junior developers, contribute to architectural decisions, and collaborate closely with frontend and DevOps teams. Their work ensures that applications are scalable, reliable, and efficient. Senior developers typically have several years of experience and deep knowledge of Python frameworks like Django or Flask.

What are the key skills and qualifications needed to thrive as a senior backend Python developer?

To thrive as a Senior Backend Python Developer, you need expertise in Python programming, strong knowledge of backend frameworks (such as Django or Flask), and experience with database management, often backed by a degree in computer science or equivalent experience. Familiarity with version control systems like Git, containerization tools like Docker, cloud platforms (e.g., AWS), and possibly certifications in cloud or Python technologies are common requirements. Outstanding problem-solving skills, effective communication, and the ability to mentor junior developers help set top performers apart. These competencies ensure the development of robust, scalable, and maintainable backend systems that support business objectives.

What are some common challenges senior backend Python developers face when working on large-scale systems?

Senior Backend Python developers working on large-scale systems often encounter challenges such as ensuring application scalability, maintaining code quality across distributed teams, and optimizing performance for high traffic. Balancing the integration of new features with legacy system constraints can also be demanding. Effective communication and collaboration with frontend teams, DevOps, and product managers are crucial for delivering reliable and maintainable backend solutions.

What is the difference between Senior Backend Python vs Backend Developer?

AspectSenior Backend PythonBackend Developer
Required CredentialsBachelor's in CS or related, 5+ years experience, Python expertiseBachelor's in CS or related, 2-4 years experience, Python knowledge
Work EnvironmentTech companies, startups, enterprise systemsTech firms, startups, software agencies
Employer & Industry UsageUsed across industries requiring scalable backend solutionsCommon in web development and software services
Search & Comparison IntentUnderstanding senior roles, responsibilities, salaryEntry to mid-level backend roles, skill requirements

Senior Backend Python professionals typically have more experience, advanced skills, and leadership responsibilities compared to Backend Developers. They often work on complex systems, mentor junior staff, and have a broader understanding of architecture. Backend Developers focus on building and maintaining backend services with less emphasis on leadership or strategic planning.

What are the most commonly searched types of Backend Python jobs in Minnesota?

The most popular types of Backend Python jobs in Minnesota are:

What cities in Minnesota are hiring for Senior Backend Python jobs?

Cities in Minnesota with the most Senior Backend Python job openings:

Senior AI ML Engineer - Remote

UnitedHealth Group

Eden Prairie, MN • On-site, Remote

$124K - $164K/yr

Full-time

Retirement

Re-posted 19 days ago


UnitedHealth Group rating

7.6

Company rating: 7.6 out of 10

Based on 146 frontline employees who took The Breakroom Quiz

192nd of 898 rated healthcare providers


Job description

Optum Tech is a global leader in health care innovation. Our teams develop cutting-edge solutions that help people live healthier lives and help make the health system work better for everyone. From advanced data analytics and AI to cybersecurity, we use innovative approaches to solve some of health care's most complex challenges. Your contributions here have the potential to change lives. Ready to build the next breakthrough? Join us to start Caring. Connecting. Growing together.

Optum Health is a patient-centered care organization serving communities nationwide by enabling high-quality, fully accountable, value-based care as part of Optum's mission to help millions of people live healthier lives. The work you do with our team directly improves health outcomes by connecting people with the care, resources, and support they need to feel their best. Join us to start Caring. Connecting. Growing together.

Position Summary

As a Senior AI/ML Engineer within the Optum Health & Financial Tech AI team, you will design and build enterprise-scale generative AI applications and agentic workflows that solve complex health and financial technology challenges. You will collaborate with cross-functional partners to develop multi-step reasoning systems, implement advanced Retrieval-Augmented Generation (RAG) pipelines, and craft responsive, full-stack experiences using modern frameworks like React, Next.js, Python, and PostgreSQL. By deploying innovative AI technologies safely and responsibly, you will directly support our mission of delivering impactful, context-aware digital solutions that improve health outcomes and operational efficiency.

You'll enjoy the flexibility to work remotely * from anywhere within the U.S. as you take on some tough challenges. For all hires in the Minneapolis or Washington, D.C. area, you will be required to work in the office a minimum of four days per week.

Primary Responsibilities:

  • Design, develop, and deploy enterprise-scale AI-powered solutions and LLM-powered applications using modern GenAI frameworks and APIs with an emphasis on the responsible use of AI
  • Develop agentic AI workflows, multi-step reasoning systems (with tool usage and memory), and advanced Retrieval-Augmented Generation (RAG) pipelines
  • Design and develop responsive frontend applications using React and Nextjs, and build backend services, APIs, and microservices using Python and Nodejs
  • Build systems for document ingestion, chunking, embeddings, semantic search, and advanced retrieval strategies (hybrid search, GraphRAG, contextual enrichment)
  • Design and optimize relational data models using PostgreSQL and integrate vector databases with relational data sources for contextual responses
  • Define end-to-end architecture spanning frontend, backend, AI, and data layers, ensuring performance, scalability, and reliability
  • Lead technical decision-making, design reviews, and code reviews, while mentoring junior engineers in AI engineering and full-stack best practices
  • Use enterprise-approved AI tools to streamline developer workflows, automate tasks, and drive continuous improvement across the development lifecycle
  • Evaluate emerging AI trends, frameworks, tools, and technologies to inform solution design, strategic innovation, and technical direction
  • Collaborate with product, business, and engineering teams to translate complex business requirements into scalable technical designs, communicating complex AI concepts to non-technical stakeholders

You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in. 

Required Qualifications:

  • Bachelor's degree or equivalent experience (such as an additional 4 years of software development experience in lieu of a degree)
  • 6 years of professional experience in software engineering or AI/ML engineering
  • 4 years of hands-on experience with frontend technologies (React, Nextjs) and backend development (Python or Nodejs, and REST APIs)
  • 3 years of experience with relational database design and optimization using PostgreSQL
  • 2 years of experience building and deploying end-to-end Generative AI and LLM-powered applications in production
  • 2 years of experience designing and implementing RAG (Retrieval-Augmented Generation) pipelines, including semantic search, embeddings, and vector databases
  • 1 years of experience with AI orchestration frameworks (such as LangChain, LangGraph, or CrewAI) or developing agentic, multi-agent AI workflows

Preferred Qualifications:

  • Bachelor's or Master's degree in Computer Science, Artificial Intelligence, Data Science, or a related technical field
  • Experience implementing hybrid search strategies, GraphRAG, and contextual enrichment patterns for document retrieval
  • Deep understanding of distributed systems, microservices architecture, and enterprise application scalability
  • Solid expertise in designing AI evaluation metrics and establishing safety guardrails for reliable model outputs
  • Proven ability to mentor engineering teams, lead technical design reviews, and establish best practices in full-stack and AI development
  • Proven excellent cross-functional communication skills, with the ability to translate complex technical AI concepts into clear business insights for stakeholders

*All employees working remotely will be required to adhere to UnitedHealth Group's Telecommuter Policy

Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The salary for this role will range from $120,100 - $214,500 annually based on full-time employment. We comply with all minimum wage laws as applicable.

Application Deadline: This will be posted for a minimum of 2 business days or until a sufficient candidate pool has been collected. Job posting may come down early due to volume of applicants.

At UnitedHealth Group, our mission is to help people live healthier lives and make the health system work better for everyone. We believe everyone-of every race, gender, sexuality, age, location and income-deserves the opportunity to live their healthiest life. Today, however, there are still far too many barriers to good health which are disproportionately experienced by people of color, historically marginalized groups and those with lower incomes. We are committed to mitigating our impact on the environment and enabling and delivering equitable care that addresses health disparities and improves health outcomes - an enterprise priority reflected in our mission.  

UnitedHealth Group is an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

UnitedHealth Group is a drug - free workplace. Candidates are required to pass a drug test before beginning employment.  

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