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Senior Assay Development Scientist Jobs in Oregon

As our Assay Development Scientist, you will be the primary architect of our internal molecular biology toolkit, transforming cutting‑edge academic and commercial protocols into robust, highly ...

Sr. R&D Scientist

White City, OR

$91K - $125K/yr

Position Summary NIC is seeking an experienced Sr. R&D Scientist to lead execution of high-performance coatings and advanced material development programs from concept through qualification, scale-up ...

Sr. R&D Scientist

White City, OR · On-site

$91K - $125K/yr

Position Summary NIC is seeking an experienced Sr. R&D Scientist to lead execution of high-performance coatings and advanced material development programs from concept through qualification, scale-up ...

Sr. R&D Scientist

White City, OR · On-site

$91K - $125K/yr

Position Summary NIC is seeking an experienced Sr. R&D Scientist to lead execution of high-performance coatings and advanced material development programs from concept through qualification, scale-up ...

... assays, adjusting your approach to accommodate nonstandard requests as needed. You will also be ... This role provides the opportunity to work cross-functionally with R&D scientists, automation ...

Apply knowledge of placental development, trophoblast differentiation, and maternal-fetal exchange ... Use imaging, histology, molecular profiling, and functional assays to evaluate trophoblast ...

Scientist - Endometrial Biology

Portland, OR · On-site

$37.50 - $47/hr

Role overview As a Scientist at e184, you will lead research aimed at understanding the molecular ... assays to study signaling and structural interactions during implantation and early development ...

Role overview As a Scientist at e184, you will lead research aimed at understanding the molecular ... assays to study signaling and structural interactions during implantation and early development ...

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Showing results 1-20

Senior Assay Development Scientist information

See Oregon salary details

$70.3K

$116.9K

$173.9K

How much do senior assay development scientist jobs pay per year?

As of Aug 22, 2026, the average yearly pay for senior assay development scientist in Oregon is $116,877.00, according to ZipRecruiter salary data. Most workers in this role earn between $96,700.00 and $132,200.00 per year, depending on experience, location, and employer.

What does a senior assay development scientist do?

A Senior Assay Development Scientist designs, optimizes, and validates biochemical or cell-based assays for research, diagnostics, or drug development. They lead assay development projects, troubleshoot technical challenges, and collaborate with cross-functional teams. Their role often includes analyzing experimental data, ensuring assay reproducibility, and maintaining compliance with regulatory standards. Additionally, they mentor junior scientists and contribute to scientific publications or regulatory submissions.

What are the key skills and qualifications needed to thrive as a senior assay development scientist?

A Senior Assay Development Scientist should possess advanced expertise in assay design, validation, and troubleshooting, supported by a degree in biochemistry, molecular biology, or a related field. Familiarity with laboratory automation platforms, high-throughput screening technologies, and software for data analysis such as Prism or SoftMax Pro is typically required. Strong project management, problem-solving, and cross-functional communication skills enhance effectiveness in leading projects and collaborating across departments. These skills are crucial for delivering robust, innovative assays that meet regulatory standards and support critical research or product development goals.

What are the typical challenges faced by a senior assay development scientist and how do they overcome them?

Senior Assay Development Scientists often encounter challenges such as optimizing assay sensitivity and specificity, troubleshooting inconsistent results, and meeting tight project timelines. To overcome these, they rely on deep scientific knowledge, rigorous method validation, and effective collaboration with other scientists, engineers, and quality assurance teams. Staying up to date on the latest technologies and regulatory requirements also helps address technical and compliance-related hurdles. By fostering open communication and drawing on multidisciplinary expertise within their teams, these professionals develop innovative solutions and ensure high-quality outcomes.

What are the most commonly searched types of Assay Development Scientist jobs in Oregon?

The most popular types of Assay Development Scientist jobs in Oregon are:

What are popular job titles related to Senior Assay Development Scientist jobs in Oregon?

For Senior Assay Development Scientist jobs in Oregon, the most frequently searched job titles are:

What cities in Oregon are hiring for Senior Assay Development Scientist jobs?

Cities in Oregon with the most Senior Assay Development Scientist job openings:

Infographic showing various Senior Assay Development Scientist job openings in Oregon as of August 2026, with employment types broken down into 89% Full Time, 9% Part Time, and 2% Contract. Highlights an 98% In-person, and 2% Hybrid job distribution, with an average salary of $116,877 per year, or $56.2 per hour.

Assay Development Scientist

Medium

Portland, OR • On-site

$80 - $120/hr

Other

Medical, Dental, Vision, Retirement, PTO

This job post has expired today. Applications are no longer accepted.


Job description

About us:

e184 Repro is a biotechnology research company with the mission of advancing in vitro gametogenesis to solve one of biology’s most profound challenges: returning the fundamental right to procreate.

We work at the frontier of cutting‑edge technology, integrating cellular reprogramming, machine learning‑guided optimization, multi‑omics analysis, and automated experimental workflows to enable gamete development for individuals facing reproductive challenges.

Role overview:

As our Assay Development Scientist, you will be the primary architect of our internal molecular biology toolkit, transforming cutting‑edge academic and commercial protocols into robust, highly standardized workflows. Your mission is to bridge the gap between “published methods” and “internal gold standards”. This role focuses on troubleshooting complex sample types, optimizing assays for low‑input requirements, and collaborating with our computational team to validate data quality through a rigorous feedback loop. Beyond the bench, you will evaluate emerging technologies, manage relationships with CROs, and spearhead our future transition toward automated liquid handling and miniaturized workflows. This is a role for a meticulous problem‑solver who is passionate about technical excellence.

What you’ll do
  • Architect the toolkit: Identify, internalize, implement, and optimize cutting‑edge assays (RNAseq, scRNAseq, ATACseq, ChIP‑seq, etc.) for our specific samples and instruments.
  • Push technology to the limit: Go beyond standard protocols and refine for ultra‑low input samples where standard methods fail.
  • Establish gold standards: Author company SOPs that ensure absolute reproducibility across the entire R&D team.
  • Drive technical QC: Partner with our computational experts to analyze sequencing data and help decide which techniques are best for our platform.
  • Bring the future: Develop new molecular biology technologies, demo high‑end equipment, and lead the charge toward miniaturization and automation via liquid handlers.
Core requirements
  • 5+ years of NGS mastery with deep, hands‑on experience in sample prep across RNAseq, DNAseq, single‑cell applications (scRNA‑seq, scATAC‑seq), and DNA methylation sequencing in a fast‑paced setting.
  • A proven track record of developing or heavily modifying assays for challenging contexts (low input, difficult sample types), not just following manual instructions.
  • Expert at interpreting Bioanalyzer/TapeStation traces and correlating library complexity with bench‑side variables.
  • Ability to translate complex technical trade‑offs into clear decisions for both scientists and engineers.
  • You are proactive, resourceful, obsessed with high‑quality data, and thrive in a startup environment of constant troubleshooting.
You’ll stand out with
  • Automation background with experience programming liquid handlers (Hamilton/Opentrons/Tecan).
  • A history of successfully miniaturizing reactions to slash costs while maintaining data integrity.
  • Experience setting up and running Illumina or Nanopore/PacBio sequencers in‑house.
Why e184?
  • Unrivaled impact: Your work directly enables technology that transforms human fertility and reproductive medicine.
  • Full‑range growth: Gain exposure to the entire lifecycle of discovery. From screening to mechanistic validation.
  • Best of both worlds: Experience the creative chaos of an early‑stage startup with the stability of a well‑capitalized company.
  • Elite collaboration: Work alongside a world‑class team who are as driven as you are.
What we offer
  • Competitive salary + equity participation is considered.
  • State‑of‑the‑art facility in Portland metro area.
  • Comprehensive Medical, Dental, Vision, and 401(k) with company match.
  • 20 days PTO + 11 paid holidays.
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