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Semi Solid Formulation Scientist Jobs (NOW HIRING)

... conventional solid, semi-solid, liquid, and other formulations and medical devices. Role ... Experience in development and formulation of oral solid dosage forms (eg. tablets, caplets ...

This position reports to the Formulation Scientist. Key Responsibilities * Iteratively design ... Proficiency in polymer characterization (solution, solid state) is required, and expertise in ...

This position reports to the Formulation Scientist. Key Responsibilities Iteratively design ... and solid state Basic understanding of electrochemistry, electronic and ionically conducting ...

Senior Scientist, Electrolyte

Woburn, MA ยท On-site +1

$100K - $136K/yr

Formulation and Materials Design * Design and develop electrolyte formulations compatible with high ... Experience with developing semi-solid electrolytes (e.g. in-situ gel polymer electrolyte, polymer ...

Experience in solid dose formulation and manufacturing (tablets). * Experience in formulation of ... Experience in formulation of semi-solids for ingestion, topical, and/or nasal application.

Experience in solid dose formulation and manufacturing (tablets). * Experience in formulation of ... Experience in formulation of semi-solids for ingestion, topical, and/or nasal application.

Senior Scientist Product Development

Summit, NJ ยท On-site

$105K - $148K/yr

Experience in solid dose formulation and manufacturing (tablets). * Experience in formulation of ... Experience in formulation of semi-solids for ingestion, topical, and/or nasal application.

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Semi Solid Formulation Scientist information

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How much do semi solid formulation scientist jobs pay per hour?

As of Jun 16, 2026, the average hourly pay for semi solid formulation scientist in the United States is $37.61, according to ZipRecruiter salary data. Most workers in this role earn between $25.24 and $43.51 per hour, depending on experience, location, and employer.

What are some common challenges faced by Semi Solid Formulation Scientists when developing new topical products?

Semi Solid Formulation Scientists often encounter challenges related to achieving the desired texture, stability, and efficacy of topical products such as creams, gels, and ointments. Balancing the formulation to ensure proper drug release, patient acceptability, and shelf-life stability can be complex due to interactions among active ingredients and excipients. Additionally, scaling up formulations from laboratory to production scale while maintaining consistency and regulatory compliance requires careful planning and collaboration with manufacturing and quality teams.

What are the key skills and qualifications needed to thrive as a Semi Solid Formulation Scientist, and why are they important?

To thrive as a Semi Solid Formulation Scientist, you need a strong background in pharmaceutical sciences, chemistry, or related fields, often supported by an advanced degree and experience in formulation development. Familiarity with analytical instruments, formulation software, and Good Manufacturing Practice (GMP) guidelines is crucial. Excellent problem-solving abilities, attention to detail, and effective teamwork and communication skills help distinguish top performers in this role. These competencies ensure the safe, effective, and scalable development of semi-solid pharmaceutical products, meeting regulatory and market demands.

What are Semi Solid Formulation Scientists?

Semi Solid Formulation Scientists are specialized professionals who develop, optimize, and test pharmaceutical products in semi-solid forms, such as creams, ointments, gels, and lotions. They work primarily in the pharmaceutical, cosmetic, or biotechnology industries to ensure these products are safe, effective, and stable. Their role includes researching ingredients, conducting laboratory experiments, and adhering to regulatory guidelines. They also collaborate with other scientists and departments to scale up production and troubleshoot formulation challenges.
Infographic showing various Semi Solid Formulation Scientist job openings in the United States as of June 2026, with employment types broken down into 71% Full Time, and 29% Contract. Highlights an 100% In-person job distribution, with an average salary of $78,236 per year, or $37.6 per hour.

Senior Scientist, Formulation and Delivery Sciences

Ionis

Carlsbad, CA โ€ข On-site

Full-time

Posted 8 days ago


Job description

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We're pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.
At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.
With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.
We're building on our rich history, and we believe our greatest achievements are ahead of us. If you're passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!
Senior Scientist, Formulation and Delivery Sciences
We seek a Senior Scientist skilled in lipid nanoparticle formulation, targeted delivery, synthesis and characterization of conjugated targeting ligands, plasma protein corona analysis and control, RNA/LNP physicochemical characterization, and in vitro/in vivo performance assessment, with a focus on elucidating and overcoming mechanistic nanoparticle delivery hurdles. The successful candidate will work hands-on with receptor-targeted lipid nanoparticle screening, biochemical conjugation strategies, affinity and cellular uptake assays, and in vivo delivery studies. Reporting to the Director of Formulation and Delivery Sciences, this individual will help identify and validate receptor-ligand strategies, establish screening workflows, and optimize targeted lipid nanoparticle systems for extrahepatic delivery. The successful candidate is a highly collaborative, detail-oriented, and creative scientist who enjoys bench research, adheres to well-defined scientific direction and group goals, and is excited to join a strong multidisciplinary team at a leading nucleic acid therapeutics company.
RESPONSIBILITIES:
  • Design, produce, and characterize receptor-targeted lipid nanoparticle formulations for in vitro and preclinical in vivo studies.
  • Help identify and prioritize receptor-ligand pairs for targeted delivery applications based on biological rationale, feasibility, and experimental performance.
  • Develop and execute ligand conjugation workflows for lipid nanoparticles using biochemical and chemical conjugation approaches.
  • Establish and apply affinity, cellular uptake, and functional screening assays to evaluate targeted lipid nanoparticle constructs across ligand formats, densities, and formulations.
  • Generate and interpret data linking receptor binding, ligand density, cellular uptake, and in vivo delivery performance.
  • Partner with scientists across formulation, chemistry, biology, and analytical functions to refine targeted lipid nanoparticle design and advance company objectives.
  • When needed, assist other team projects with LNP production, in vivo testing, and downstream tissue collection and analysis.
  • Support routine in vivo studies and downstream tissue analysis, including coordination of sample collection and evaluation of distribution and activity readouts.
  • Thoroughly document results in notebooks and written reports, and present findings to cross-functional teams and at research meetings.
  • Contribute to publications, patent applications, and the continued development of Ionis targeted delivery capabilities.

QUALIFICATIONS:
  • PhD in Biochemistry strongly preferred; Chemistry, Chemical Engineering, Biophysics, Biomedical Engineering, Bioengineering, Pharmaceutics, or a related field will also be considered.
  • Minimum of 2 years of relevant industry experience following completion of a PhD or postdoctoral training.
  • Demonstrated experience with lipid nanoparticles, RNA therapeutics, receptor-targeted delivery, ligand conjugation, or related nanoparticle systems.
  • Excellent bench laboratory skills with a strong interest in hands-on experimental work and day-to-day laboratory execution.
  • High attention to detail, strong experimental rigor, and consistent documentation habits.
  • Self-motivated, able to stay on track with assigned goals and scientific direction, values collaboration, and thrives as part of a close-knit, high-performing team.
  • Creative and thoughtful problem solver who is open to adopting AI-enabled tools to improve research efficiency.
  • Hands-on experience with biochemical, biophysical, and analytical methods used to characterize ligands, lipid nanoparticles, and targeted delivery performance.
  • Experience with cell-based uptake or activity assays and supporting in vivo studies for targeted delivery platforms is highly desirable.
  • Proven skills in experimental design, data interpretation, formal oral and written communication, and cross-functional collaboration.

Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position; reference requisition # IONIS004054
Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits
Full Benefits Link: https://ionis.com/careers#:~:text=Highly%20competitive%20benefits
The pay scale for this position is $113,156 - $149,750.00
NO PHONE CALLS PLEASE. PRINCIPALS ONLY.
Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws.
For further information, please review the Know Your Rights notice from the Department of Labor.