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Sema4 Genomics Jobs (NOW HIRING)

SEMA4

VP, Program Management

Manhattan, NY · On-site

Sema4 is transforming healthcare by applying AI and machine learning to multidimensional, longitudinal clinical and genomic data to build dynamic models of human health and defining optimal ...

SEMA4

Client Executive - Remote - Sioux Falls, SD

Stamford, CT · On-site +1

$81K - $110K/yr

... Sema4 and the partner health system are making in realigning the care deliver model around genomic medicine and insights being developed to help providers and patients engage with care in a more ...

SEMA4

Product Analyst - Data Platform

Manhattan, NY · On-site

Sema4 is transforming healthcare by applying AI and machine learning to multidimensional, longitudinal clinical and genomic data to build dynamic models of human health and defining optimal ...

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$104K

$127K

$147.5K

How much do sema4 genomics jobs pay per year?

As of Jun 7, 2026, the average yearly pay for sema4 genomics in the United States is $127,000.00, according to ZipRecruiter salary data. Most workers in this role earn between $115,500.00 and $138,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Genomics Specialist at Sema4, and why are they important?

To thrive as a Genomics Specialist at Sema4, you generally need a strong background in molecular biology, genetics, and bioinformatics, often supported by a relevant advanced degree. Familiarity with next-generation sequencing (NGS) platforms, data analysis software, and laboratory information management systems (LIMS) is typically required. Attention to detail, critical thinking, and effective communication are crucial soft skills for interpreting complex data and collaborating with multidisciplinary teams. These skills and qualifications are essential to ensure accurate genomic analysis and contribute to advancements in precision medicine.

What are some common challenges faced by professionals working in a genomics company like Sema4 Genomics, and how can they be addressed?

Professionals at Sema4 Genomics often encounter challenges such as managing and interpreting large volumes of complex genomic data, staying updated with rapidly evolving technologies, and ensuring compliance with strict data privacy regulations. To address these, teams frequently collaborate across disciplines, participate in ongoing training, and leverage advanced bioinformatics tools. Additionally, clear communication with clinicians and researchers helps bridge gaps between science and patient care, promoting both accuracy and innovation in their work.

What is Sema4 Genomics?

Sema4 Genomics is a health intelligence company that specializes in genomic testing and data analytics to provide insights into health, disease, and personalized medicine. The company offers a range of genetic testing services, including carrier screening, hereditary cancer testing, and whole exome sequencing. Sema4 uses advanced bioinformatics and data science to interpret genetic data, helping healthcare providers and patients make informed decisions about medical care. Their goal is to improve health outcomes through precision medicine and by advancing our understanding of the genetic basis of disease.

What is the difference between Sema4 Genomics vs Genetic Counselor?

AspectSema4 GenomicsGenetic Counselor
CredentialsBioinformatics, genetics, or related degreesMaster's in Genetic Counseling, certification (ABGC)
Work EnvironmentHealthcare or biotech companies, research labsHospitals, clinics, healthcare settings
Industry UsageGenomic testing, data analysis, researchPatient counseling, risk assessment, education

Sema4 Genomics professionals focus on genomic data analysis and research, often working in biotech or research settings. Genetic Counselors primarily work directly with patients to interpret genetic tests and provide counseling. While both roles require genetics knowledge, Sema4 Genomics roles are more data and research-oriented, whereas Genetic Counselors focus on patient interaction and clinical guidance.

What cities are hiring for Sema4 Genomics jobs? Cities with the most Sema4 Genomics job openings:
What job categories do people searching Sema4 Genomics jobs look for? The top searched job categories for Sema4 Genomics jobs are:
Sema4 Genomics jobs near you
Infographic showing various Sema4 Genomics job openings in the United States as of May 2026, with employment types broken down into 94% Full Time, 3% Part Time, and 3% Contract. Highlights an 91% Physical, 1% Hybrid, and 8% Remote job distribution, with an average salary of $127,000 per year, or $61.1 per hour.
Bioinformatics Scientist, Translational Oncology

Bioinformatics Scientist, Translational Oncology

SEMA4

Stamford, CT • On-site

Full-time

Posted 29 days ago

Job description

Sema4 is a patient-centered health intelligence company dedicated to advancing healthcare through data-driven insights. Sema4 is transforming healthcare by applying AI and machine learning to multidimensional, longitudinal clinical and genomic data to build dynamic models of human health and defining optimal, individualized health trajectories. Centrellis®, our innovative health intelligence platform, is enabling us to generate a more complete understanding of disease and wellness and to provide science-driven solutions to the most pressing medical needs. Sema4 believes that patients should be treated as partners, and that data should be shared for the benefit of all.
We are looking for a talented Bioinformatics Scientist, Translational Oncology to lead and support projects that translate genomic results and/or clinical EMR datasets into novel discoveries. You will aid in the design and development of Sema4's databases and associated data analytics. This role will serve as a SME in genomics, cancer biology and clinical oncology.
RESPONSIBILITIES
  • Lead translational research projects in collaboration with oncologists and basic scientists using Sema4's unique data resources.
  • Contribute to automated extraction of key data elements from EMR
  • Ability to evaluate available literature and other data sources such ClinVar, cBioPortal, TCGA, NCBI, Ensembl, Broad FireHose, etc.
  • Present research findings to stakeholders
  • Publish novel findings in academic journals and present at conferences

QUALIFICATIONS
  • PhD in Bioinformatics, Biomedical Informatics, Computational Biology, Genomics, or a related discipline. We will also consider MDs with training in oncology and/or Biomedical Informatics.
  • Minimum 2-3 years of Post-Doctoral or Industry experience.
  • Strong computational and analytical skills.
  • Deep understanding of genomics, cancer biology or clinical oncology. Experience in oncology is highly preferred.
  • Excellent written and verbal communicator.
  • Experience working on interdisciplinary teams that include scientists, programmers, and clinicians.
  • Proficiency in one or more programming languages including Python, R and SQL; familiarity with Linux environments and exposure to cloud infrastructures such as AWS.
  • Interest in data science and machine learning approaches to solving complex problems.
  • Experience of developing and documenting high-quality code using version control tools (especially Git) and software issue tracking/management systems (especially Jira).
  • Highly motivated, great ability to work independently or as part of a team.
  • Track record of publishing high impact peer-reviewed research articles.

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