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Scientist Cell Culture Process Development Jobs (NOW HIRING)

Vertex Pharmaceuticals LLC

$125 - $150/hr

Vertex is seeking a talented individual to join our Process Development team as a Scientist. The ... Develop expertise in pluripotent stem cell culture and differentiation to support process ...

Amgen, Inc.

Process Development Associate

Cambridge, MA · On-site

Process Development Associate What you will do Let's do this. Let's change the world. In this vital ... This role is within an integrated organization in which cell culture and purification scientists ...

Amgen

Process Development Associate

Cambridge, MA · On-site

Process Development Associate What you will do Let's do this. Let's change the world. In this vital ... This role is within an integrated organization in which cell culture and purification scientists ...

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How much do scientist cell culture process development jobs pay per hour?

As of Sep 8, 2026, the average hourly pay for scientist cell culture process development in the United States is $38.66, according to ZipRecruiter salary data. Most workers in this role earn between $28.37 and $46.15 per hour, depending on experience, location, and employer.

What does a scientist in cell culture process development do?

A Scientist in Cell Culture Process Development is responsible for designing, optimizing, and scaling up processes to grow cells in laboratory settings, primarily for the production of biologics such as therapeutic proteins, vaccines, or cell-based therapies. They work to improve cell growth conditions, monitor cell health, and develop protocols that can be transferred from the lab to manufacturing scale. Their work is critical to ensuring products are produced efficiently, safely, and with high quality for clinical or commercial use.

What are the key skills and qualifications needed to thrive as a scientist in cell culture process development?

To thrive as a Scientist in Cell Culture Process Development, you need a solid background in cell biology, bioprocess engineering, and hands-on experience with mammalian cell culture, typically supported by an advanced degree in a life science discipline. Familiarity with bioreactor systems, analytical assays, and software for data analysis such as JMP or Prism is often required, along with knowledge of regulatory guidelines. Strong problem-solving skills, meticulous attention to detail, and effective teamwork are standout soft skills for this role. These competencies are crucial for optimizing cell culture processes, ensuring experimental reproducibility, and supporting the development of safe and effective biopharmaceutical products.

What are some common challenges faced by scientists in cell culture process development, and how are they typically addressed?

Scientists in cell culture process development often encounter challenges such as maintaining cell line stability, optimizing growth conditions, and ensuring consistent product yield and quality. These challenges are typically addressed by rigorous experimental design, close monitoring of critical process parameters, and leveraging automation for reproducibility. Collaboration with analytical, quality assurance, and upstream/downstream teams is common to troubleshoot issues and refine processes. Staying updated with the latest bioprocessing technologies and regulatory guidelines also helps in overcoming these hurdles.

What is the difference between Scientist Cell Culture Process Development vs Scientist Bioprocess Development?

AspectScientist Cell Culture Process DevelopmentScientist Bioprocess Development
CredentialsBachelor's/Master's in Life Sciences, Biotechnology, or related fieldsBachelor's/Master's in Chemical/Biological Engineering, Life Sciences
Work EnvironmentLaboratories focused on cell culture, bioreactors, and media optimizationBioprocessing facilities, pilot plants, and manufacturing environments
Industry UsagePrimarily in biotech and pharmaceutical companies developing cell-based therapiesIn biotech, pharma, and contract manufacturing organizations

Scientist Cell Culture Process Development focuses on optimizing and developing cell culture methods, media, and conditions for producing biological products. In contrast, Scientist Bioprocess Development encompasses a broader scope, including scaling up processes, bioreactor design, and process validation. Both roles require similar educational backgrounds but differ in their specific focus areas within biomanufacturing.

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What are popular job titles related to Scientist Cell Culture Process Development jobs?

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Scientist Cell Culture Process Development jobs near you
Infographic showing various Scientist Cell Culture Process Development job openings in the United States as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 82% Full Time, 14% Part Time, and 2% Contract. Highlights an 87% Physical, 2% Hybrid, and 11% Remote job distribution, with an average salary of $80,420 per year, or $38.7 per hour.

Senior Scientist - Lentiviral Vector Upstream Process Development

Reading, PA • On-site

Johnson and Johnson
See more jobs at Johnson and Johnsonexternal

$72K - $99K/yr

Full-time

Posted 19 days ago

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.
As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.
Job Function:
Discovery & Pre-Clinical/Clinical Development
Job Sub Function:
Biotherapeutics R&D
Job Category:
Scientific/Technology
All Job Posting Locations:
Spring House, Pennsylvania, United States of America
Job Description:
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal.
Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.
As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.
We are searching for the best talent for a Senior Scientist - Lentiviral Vector Upstream Process Development to be based in Spring House, PA.
Purpose:
The Senior Scientist, Lentiviral Vector Upstream Process Development, will lead development, optimization, and characterization of scalable cell culture processes for cell therapy and CAR-T programs. This role will provide scientific leadership for early- or clinical-stage process development, with emphasis on cell culture and bioreactor execution at varying scales and data-driven process understanding, platform robustness and knowledge and optimization of upstream process technologies. This role will also support technology transfer to Johnson & Johnson's manufacturing sites, commercial manufacturing investigations and provide subject matter expert knowledge as part of life cycle management for cell therapy products in Johnson & Johnson's pipeline.
You will be responsible for:
  • Design and execute upstream process development studies for lentiviral therapeutic products and provide scientific guidance.
  • Conduct cell culture experiments using shake flasks, bench-scale bioreactors, and automated high-throughput systems.
  • Contribute to development of lentiviral processes to continuously improve productivity, quality, and manufacturability.
  • Perform technology transfer to and collaborate with Johnson & Johnson's manufacturing sites
  • Support existing and new commercial manufacturing investigations and provide subject matter expert knowledge as part of product life cycle management
  • Apply statistical experimental design, data analytics, and online monitoring and visualization tools to strengthen upstream process understanding.
  • Analyze and interpret process data using JMP, MiniTab, Python, Spotfire, or similar platforms.
  • Evaluate emerging novel upstream technologies that improve process robustness and development efficiency.
  • Collaborate closely with downstream, analytical, formulation, modeling, automation to align study design and deliverables
  • Mentor junior scientists and provide scientific leadership across programs and cross-functional workstreams.
  • Author technical reports, development summaries, scientific presentations, protocols, and regulatory-supporting documentation.

Qualifications:
Required:
  • PhD in Chemical Engineering, Biochemical Engineering, Biological Sciences, Biotechnology, or related field with 2+ years of relevant experience; OR BS or MS with 4-6 years of relevant experience.
  • Experience with process development of viral based products.
  • Experience in mammalian cell culture process development for biologics, cell and gene therapy, RNA therapeutics, or related viral vector modalities.
  • Hands-on experience with cell culture, bioreactor operation, media optimization, process monitoring, and process scale-up.
  • Strong data analysis, experimental design, and technical documentation skills.
  • Demonstrated ability to independently design, execute, interpret, and communicate complex studies.
  • Excellent written and verbal communication skills.
  • Ability to work effectively in cross-functional team environments.
  • Previous experience with technology transfer of a bioprocess to clinical or commercial GMP manufacturing is strongly preferred
  • Occasional weekend work may be required
  • Up to 10% domestic and international travel may be required

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.
Required Skills:
Preferred Skills:
Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Consulting, Critical Thinking, Drug Discovery Development, Emerging Technologies, Molecular Diagnostics, Pharmacogenetics, Pharmacovigilance, Process Improvements, Quality Assurance (QA), Relationship Building, Research Documents, Scientific Research, Technologically Savvy

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