The qualifications to work in a science museum depend largely on your specific responsibilities. If you are a curator or researcher, you need to have a background in science and training or an advanced degree in museum studies to coordinate exhibits properly. Development aids and associates should have a bachelor’s degree in finance, business administration, or a closely related field. Security guards and tour guides may only need a high school diploma. Jobs at science museums also require strong verbal communication skills and an interest in science and education.