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Scale Up Engineer Jobs (NOW HIRING)

MONOSOL LLC

Senior Process Development Engineer

Chicago, IL · On-site

$102.99K - $169.23K/yr

Process Experiments and Scale-Up * Propose, design, prioritize, and safely execute laboratory ... Apply fundamental engineering principles and scale-up laws to guide process design and scale-up ...

MONOSOL LLC

Senior Process Development Engineer

Chicago, IL

$107.10K - $138.50K/yr

Process Experiments and Scale-Up * Propose, design, prioritize, and safely execute laboratory ... Apply fundamental engineering principles and scale-up laws to guide process design and scale-up ...

Glenmark Pharmaceuticals

Research Officer

Monroe, NC · On-site

OVERALL JOB RESPONSIBILITIES Responsibilities Results Expected/ Target Prepare protocols/Batch Records for scale-up, Engineering Batches for the new products. Create gap analysis reports, risk ...

Beyond

Process Engineer

El Segundo, CA · On-site

$100K - $115K/yr

The Process Engineer will focus on food process engineering, process development, and scale-up, ensuring manufacturing systems consistently deliver high-quality products that meet defined ...

Developlus, Inc.

Technical Quality Engineer

Corona, CA · On-site

$74.30K - $95.90K/yr

Technical Quality Engineer - Scale-Up & Cleaning Validation Department: Quality Assurance Reports To: Quality Manager / Quality Engineering Supervisor Location: Corona, CA - Magnolia Facility ...

Bluestem Biosciences

Senior Proccess Engineer

Omaha, NE

$99.50K - $128.70K/yr

Execute and the process scale-up strategy, designing and executing experiments that advance the technology readiness level (TRL) to pre-commercial demonstration (TRL 7). * Analyze and interpret data ...

Bluestem Biosciences

Senior Proccess Engineer

Omaha, NE · On-site

$99.50K - $128.70K/yr

Execute and the process scale-up strategy, designing and executing experiments that advance the technology readiness level (TRL) to pre-commercial demonstration (TRL 7). * Analyze and interpret data ...

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How much do scale up engineer jobs pay per year?

As of May 30, 2026, the average yearly pay for scale up engineer in the United States is $115,864.00, according to ZipRecruiter salary data. Most workers in this role earn between $83,000.00 and $151,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Scale Up Engineer, and why are they important?

To thrive as a Scale Up Engineer, you need a solid background in chemical or process engineering, strong analytical skills, and experience with process optimization, typically backed by a relevant engineering degree. Familiarity with simulation software (such as Aspen Plus or HYSYS), process control systems, and safety regulations is essential, and professional certifications like a PE license can be advantageous. Strong problem-solving abilities, attention to detail, and effective communication are crucial soft skills that help coordinate cross-functional teams and drive project success. These skills and qualifications are vital for ensuring efficient, safe, and cost-effective scaling of processes from lab to full production.

What are some common challenges Scale Up Engineers face when transitioning processes from the laboratory to full production scale?

Scale Up Engineers often encounter challenges such as maintaining product consistency, addressing unexpected equipment limitations, and optimizing process efficiency during the transition from lab-scale to production-scale operations. Variations in mixing, heat transfer, and material handling can cause unforeseen issues that require creative problem-solving and close collaboration with cross-functional teams, including R&D, manufacturing, and quality assurance. Proactively identifying scale-dependent variables and conducting pilot studies can help mitigate risks and ensure a smooth scale-up process.

What are Scale Up Engineers?

Scale Up Engineers are professionals who specialize in increasing the production capacity of processes or technologies, typically in industries like chemical, pharmaceutical, or manufacturing. They take processes developed at a laboratory or pilot scale and design methods to replicate them efficiently and safely at a commercial or industrial scale. Their responsibilities include process optimization, equipment selection, troubleshooting, and ensuring that scaling up maintains product quality and safety standards. Scale Up Engineers work closely with R&D, operations, and quality teams to ensure successful and cost-effective scale transitions.

What is the difference between Scale Up Engineer vs Process Engineer?

AspectScale Up EngineerProcess Engineer
Required CredentialsBachelor's in Engineering, Chemical, Mechanical, or related fields; often some experience in manufacturing or process developmentBachelor's or higher in Chemical, Industrial, or Mechanical Engineering; certifications like Six Sigma are common
Work EnvironmentManufacturing plants, R&D labs, or industrial facilities focusing on scaling production processesManufacturing, chemical plants, or process development settings focusing on optimizing processes
Employer & Industry UsageTech companies, chemical, pharmaceutical, and manufacturing firms involved in scaling productionIndustries focused on process improvement, quality control, and efficiency in manufacturing

While both roles involve engineering in manufacturing settings, a Scale Up Engineer focuses on increasing production capacity and scaling processes, whereas a Process Engineer emphasizes optimizing and improving existing processes. The roles often overlap but differ mainly in scope: scaling vs. refining processes.

What cities are hiring for Scale Up Engineer jobs? Cities with the most Scale Up Engineer job openings:
What states have the most Scale Up Engineer jobs? States with the most job openings for Scale Up Engineer jobs include:
Scale Up Engineer jobs near you
Senior Process Development Engineer

Senior Process Development Engineer

MONOSOL LLC

Chicago, IL • On-site

$102.99K - $169.23K/yr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted yesterday

Job description

The Senior Process Development Engineer is responsible for leading complex process research and development activities to enable the successful scale-up, optimization, and industrialization of new and existing products. The role focuses on developing robust manufacturing processes, applying scale-up laws, and building process models for existing or new unit operations. The position combines experimental work, process modeling and simulation, and technical leadership to support business objectives while ensuring compliance with safety, quality, and regulatory standards.
Key Responsibilities
Leadership and Direction
  • Communicate and execute local action plans aligned with the function's strategy and the broader organization's mission and vision.
  • Demonstrate strong leadership behaviors, including effective communication, accountability, and proactive problem solving.
  • Provide technical leadership within process R&D programs and across cross-functional teams.

Process Research and Development
  • Lead and manage significant elements of the organization's process R&D program, with accountability for process development, scale-up, and technology transfer.
  • Develop new manufacturing processes for new products, with a strong emphasis on process design, robustness, and scalability.
  • Identify new process opportunities and conduct innovative experimental and modeling work to translate laboratory concepts into manufacturable solutions.

Process Experiments and Scale-Up
  • Propose, design, prioritize, and safely execute laboratory, pilot-scale, and scale-up experiments.
  • Apply fundamental engineering principles and scale-up laws to guide process design and scale-up decisions.
  • Interpret experimental data and integrate scientific and engineering principles into process development projects.

Process Modeling, Data, and Analytics
  • Develop and apply process models for existing and new unit operations using appropriate modeling, simulation, and statistical tools.
  • Use data analysis, statistical methods, and modeling to evaluate hypotheses, predict performance, and optimize processes.
  • Define and lead execution of data and analytics reporting strategies, ensuring results are communicated in a clear, actionable manner to stakeholders.

Methodologies, Tools, and Continuous Improvement
  • Identify gaps or shortcomings in current process development methodologies, tools, and workflows.
  • Propose, implement, and standardize improved process development, modeling, and scale-up practices.
  • Develop and validate new test methods and process characterization techniques as required.

Communication and Collaboration
  • Write clear technical reports documenting process development work, experimental results, and modeling outcomes.
  • Present technical findings to R&D, operations, and management, and communicate effectively across functions and sites.
  • Engage with external partners, suppliers, customers, and development collaborators as needed to support process development goals.

Innovation and Intellectual Property
  • Contribute to innovation through the development of novel processes, unit operations, and modeling approaches.
  • Understand intellectual property related to process and manufacturing technologies and support invention disclosures, patent analyses, and interactions with patent counsel.
  • Maintain awareness of external technological advances and competitive process technologies.

Project and Portfolio Management
  • Plan and deliver process development projects or workstreams using appropriate project management methodologies.
  • Balance technical depth with project execution to ensure milestones are achieved on time and within scope.
  • Act as a process R&D representative on strategic and cross-functional business teams.

People Development
  • Provide technical guidance, coaching, and mentoring to junior engineers, scientists, and technicians.
  • Support capability building within the team through training, knowledge sharing, and best-practice development.

Safety, Quality, and Compliance
  • Comply with and actively support R&D and laboratory safety programs.
  • Assume responsibility for assigned lab, pilot, or process areas, including safety, quality, and maintenance standards.

Required Skills and Competencies
  • Advanced knowledge of process engineering principles, including scale-up laws and unit operations.
  • Strong background in process modeling, simulation, and data analysis.
  • Proficiency with analytical, statistical, and scientific software used for modeling and process development.
  • Ability to manage complexity, optimize work processes, and apply continuous improvement principles.
  • Strong communication, collaboration, and stakeholder management skills.

Education and Experience
  • Bachelor's degree in Chemical Engineering, Process Engineering, or a related engineering discipline (Master's or PhD preferred).
  • Typically 5+ years of experience in process R&D, scale-up, or manufacturing process development.
  • Demonstrated experience in process modeling, simulation, and data-driven decision making.
  • Experience mentoring or supervising junior engineers or technicians is preferred.

Additional information
Applicable only to applicants applying to a position in any location with a pay disclosure requirements under state or local law:
  • The compensation range that is described below is the possible base pay compensation that the company believes in good faith that it will pay for this role at the time of posting based on job grade for the position. Individual compensation within this range is based on many factors such as years of experience etc. so the company might pay more or less than the posted range and it is understood that this range may be modified in the future.
  • In addition to base compensation, MonoSol provides a yearly incentive compensation bonus, a profit sharing bonus when eligible, a comprehensive benefits package including medical, dental, vision insurances, short term disability, long term disability, accidental death and dismemberment, term life insurance, voluntary term life insurance, transit flexible spending account (if applicable), employee assistance program, identity theft protection, 401k and paid time off (vacation and sick days).

Compensation range - $102,994.61 - $169,225.50
Incentive Compensation Bonus Target - 10% - 15%
Paid time off amount - 15 days
CLOSING
The above statements are intended to describe the general nature and level of the work being performed by employees assigned to this position. This is not intended as an exhaustive list of all responsibilities, duties, and skills required. MonoSol, LLC reserves the right to make changes to the job description whenever necessary.
DISCLAIMER
As part of MonoSol, LLC's employment process, finalist candidates will be required to complete a drug/alcohol test, physical, and background check prior to employment commencing. MonoSol, LLC is an equal opportunity employer. All qualified applicants will be considered without regard to race, national origin, gender, age, disability, sexual orientation, veteran status, or marital status.

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