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Sanger Sequencing Jobs (NOW HIRING)

Tempus

$110K - $114K/yr

... Sanger sequencing, microarray, and MLPA Maintain expertise in clinical and technical aspects related to the specific position and communicate with other internal departments to resolve/ escalate ...

AllSTEM Connections

Scientist - II

Rahway, NJ · On-site

$103K - $110K/yr

Experience with DNA sequencing technologies, including Sanger sequencing, and sequencing data analysis. * Strong organizational skills with the ability to manage multiple experiments, maintain ...

Howard University

CZI Post Doctoral Fellow

Washington, DC · On-site

$60K - $70K/yr

Designing studies, conducting genomic sequencing (including whole genome sequencing, Sanger sequencing, and single-nucleotide polymorphism (SNP) genotyping). * Analyzing data, interpreting findings ...

Tempus

$100 - $125/hr

Familiarity with diagnostic testing methodologies, including next-generation and Sanger sequencing, microarray, and MLPA * Maintain expertise in clinical and technical aspects related to the specific ...

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Sanger Sequencing information

What is Sanger sequencing?

Sanger sequencing is a DNA sequencing method developed by Frederick Sanger in 1977. It works by selectively incorporating chain-terminating dideoxynucleotides during DNA replication, producing DNA fragments of varying lengths that can be separated and read to determine the DNA sequence. This technique is widely used for sequencing small DNA fragments, validating next-generation sequencing results, and identifying genetic mutations. Despite the rise of newer sequencing technologies, Sanger sequencing remains a gold standard for accuracy in genomics research and diagnostics.

What are the key skills and qualifications needed to thrive as a Sanger sequencing technician?

To thrive as a Sanger Sequencing Technician, you need a solid background in molecular biology and genetics, often supported by a relevant degree or laboratory experience. Familiarity with PCR, capillary electrophoresis systems, and sequencing analysis software is typically required, along with knowledge of standard lab safety protocols. Attention to detail, strong organizational skills, and the ability to troubleshoot are important soft skills for handling samples and interpreting results accurately. These skills ensure reliable data generation, minimize errors, and support research or diagnostic outcomes in scientific and clinical settings.

What are some common challenges faced by professionals working in Sanger sequencing labs, and how can they be addressed?

Professionals in Sanger sequencing labs often encounter challenges such as sample contamination, low-quality DNA templates, and ambiguous sequencing results. Addressing these issues requires meticulous sample preparation, rigorous adherence to lab protocols, and routine calibration of equipment. Collaboration with colleagues, troubleshooting protocols, and staying updated on best practices can also help mitigate these common challenges. Additionally, effective communication within the team ensures that problems are quickly identified and resolved, maintaining high-quality results.

What is the difference between Sanger Sequencing vs PCR Technician?

AspectSanger SequencingPCR Technician
Primary RoleDNA sequencing to determine nucleotide orderPerforming PCR to amplify DNA segments
Required SkillsDNA analysis, sequencing protocols, data interpretationPCR setup, sample preparation, gel electrophoresis
Work EnvironmentLaboratories focused on genetic analysisResearch labs, clinical labs, biotech companies
CertificationsOften requires molecular biology or genetics trainingSimilar certifications in molecular biology or lab techniques

While both roles involve molecular biology techniques, Sanger Sequencing focuses on DNA sequencing, whereas PCR Technicians specialize in DNA amplification. Both positions require laboratory skills and knowledge of genetic methods, but their primary functions differ in purpose and workflow.

What other helpful pages are available for Sanger Sequencing?

Other pages related to Sanger Sequencing:

Infographic showing various Sanger Sequencing job openings in the United States as of September 2026, with employment types broken down into 89% Full Time, 9% Part Time, and 2% Contract. Highlights an 80% Physical, 3% Hybrid, and 17% Remote job distribution.

Clinical Genomic Scientist II (genome analyst): REMOTE, USA

Remote

Tempus
See more jobs at Tempusexternal

$110K - $114K/yr

Full-time

Re-posted 3 days ago

Job description

Compensation:

$110,000-$114,000 annually

Clinical Genomics Scientist II - Remote US:

Experienced reporting position for individuals, typically genetic counselors or PhD scientists, with clinical laboratory experience.

Responsibilities include:

interpreting diagnostic test results, review and summary of relevant medical literature, and/or review and summary of clinical information. The Clinical Genomic Scientist II is highly proficient in variant classification guidelines and in following report generation protocols to meet requirements for quality and turnaround time. The Clinical Genomic Scientist II has an understanding of genomic technologies and may assist in technical troubleshooting as needed. Additional responsibilities as designated by the Supervisor/Manager, which may include providing input in the development of guidelines and/or assisting with training of new Clinical Genomic Scientists.

Essential Functions:

Attend and provide input at trainings regarding reporting protocols applicable to the specific position or specialty

Leverage awareness of current process and systems to provide suggestions for improvements

Maintain expertise in clinical and technical aspects relevant to the specific position

Interpret clinical diagnostic testing results in accordance with established SOPs

Variant assessment and classification

Independently draft clear, accurate clinical testing results

Effective communication and collaboration with team colleagues; ability to regularly provide input and receive feedback in team discussions

Other duties as assigned

Qualifications:

Ph.D. in Molecular Biology, Genetics, or related scientific field or MS in Genetic Counseling from an accredited institution or MS in Genetics, Molecular Biology, Biochemistry, or other similar field of study

2+ years of experience in at least one of the following areas: primary genetics literature review, variant classification, genetic evidence summary writing, clinical report drafting, or sequencing result analysis

Thorough and ongoing knowledge of current theories and principles of human genetics

Ability to understand and evaluate genetic data and literature

Excellent written and verbal communication skills Enthusiasm and ability to work in and contribute to a fast-paced, highly collaborative environment

Familiarity with diagnostic testing methodologies, including next-generation and Sanger sequencing, microarray, and MLPA

Maintain expertise in clinical and technical aspects related to the specific position and communicate with other internal departments to resolve/ escalate issues as appropriate

Must possess strong working knowledge of human genetics and diagnostic genetic testing concept

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