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Sanger Sequencing Jobs (NOW HIRING)

Integral Molecular

Research Technician

Philadelphia, PA · On-site

$18.25 - $25/hr

Experience with molecular biology techniques such as (PCR, E. coli transformation, Sanger sequencing and analysis) * Experience performing quality control assays * Previous general work experience ...

UPMC

Genetics Physician

Pittsburgh, PA · On-site

Evaluate and report clinical genetics and genomics cases, including carrier screening, Sanger sequencing, quantitative RT PCR, and NGS. * Provide technical and compliance oversight for the clinical ...

Integral Molecular

Research Technician

Philadelphia, PA · On-site

$18.25 - $25/hr

Experience with molecular biology techniques such as (PCR, E. coli transformation, Sanger sequencing and analysis) * Experience performing quality control assays * Previous general work experience ...

Real Soft, Inc.

Genomics Technician

Chicago, IL · On-site

$41.91/hr

These technologies include Single-Cell Genomics, Next-Generation Sequencing, Micro-arrays, Sanger Sequencing as well as general nucleic acid sample QC and processing. The facility is part of the ...

VIVA USA INC

Genomics Technician

Chicago, IL · On-site

These technologies include Single-Cell Genomics, Next-Generation Sequencing, Micro-arrays, Sanger Sequencing as well as general nucleic acid sample QC and processing. The facility is part of the ...

Ambry Genetics

$110K - $114K/yr

... Sanger sequencing, microarray, and MLPA Maintain expertise in clinical and technical aspects related to the specific position and communicate with other internal departments to resolve/ escalate ...

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Sanger Sequencing information

What is Sanger sequencing?

Sanger sequencing is a DNA sequencing method developed by Frederick Sanger in 1977. It works by selectively incorporating chain-terminating dideoxynucleotides during DNA replication, producing DNA fragments of varying lengths that can be separated and read to determine the DNA sequence. This technique is widely used for sequencing small DNA fragments, validating next-generation sequencing results, and identifying genetic mutations. Despite the rise of newer sequencing technologies, Sanger sequencing remains a gold standard for accuracy in genomics research and diagnostics.

What are the key skills and qualifications needed to thrive as a Sanger sequencing technician?

To thrive as a Sanger Sequencing Technician, you need a solid background in molecular biology and genetics, often supported by a relevant degree or laboratory experience. Familiarity with PCR, capillary electrophoresis systems, and sequencing analysis software is typically required, along with knowledge of standard lab safety protocols. Attention to detail, strong organizational skills, and the ability to troubleshoot are important soft skills for handling samples and interpreting results accurately. These skills ensure reliable data generation, minimize errors, and support research or diagnostic outcomes in scientific and clinical settings.

What are some common challenges faced by professionals working in Sanger sequencing labs, and how can they be addressed?

Professionals in Sanger sequencing labs often encounter challenges such as sample contamination, low-quality DNA templates, and ambiguous sequencing results. Addressing these issues requires meticulous sample preparation, rigorous adherence to lab protocols, and routine calibration of equipment. Collaboration with colleagues, troubleshooting protocols, and staying updated on best practices can also help mitigate these common challenges. Additionally, effective communication within the team ensures that problems are quickly identified and resolved, maintaining high-quality results.

What is the difference between Sanger Sequencing vs PCR Technician?

AspectSanger SequencingPCR Technician
Primary RoleDNA sequencing to determine nucleotide orderPerforming PCR to amplify DNA segments
Required SkillsDNA analysis, sequencing protocols, data interpretationPCR setup, sample preparation, gel electrophoresis
Work EnvironmentLaboratories focused on genetic analysisResearch labs, clinical labs, biotech companies
CertificationsOften requires molecular biology or genetics trainingSimilar certifications in molecular biology or lab techniques

While both roles involve molecular biology techniques, Sanger Sequencing focuses on DNA sequencing, whereas PCR Technicians specialize in DNA amplification. Both positions require laboratory skills and knowledge of genetic methods, but their primary functions differ in purpose and workflow.

What other helpful pages are available for Sanger Sequencing?

Other pages related to Sanger Sequencing:

Infographic showing various Sanger Sequencing job openings in the United States as of September 2026, with employment types broken down into 89% Full Time, 9% Part Time, and 2% Contract. Highlights an 80% Physical, 3% Hybrid, and 17% Remote job distribution.

Assistant Professor Clinical Practice, Pathology Faculty

Galveston, TX • On-site

UTMB Health
See more jobs at UTMB Healthexternal

Full-time

Re-posted 25 days ago

UTMB Health rating

7.2

Company rating: 7.2 out of 10

Based on 172 frontline employees who took The Breakroom Quiz

344th of 898 rated healthcare providers

Job description

ESSENTIAL JOB FUNCTIONS:
Primary responsibilities will include, but are not limited to, performing clinical services to encompass a wide range of clinical responsibilities including performing, interpreting and issuing reports of molecular pathology diagnostic laboratory tests. This will include CMA, NGS, FISH, Sanger sequencing, and real-time PCR for oncology and inherited diseases. In addition, the faculty member will participate in the teaching of pathology residents, fellows, medical students, and lab technologist trainees. They will also attend and participate in intra and inter-departmental conferences, pursue scholarly activities to include research, publications and presentations at national and international meetings, participate in departmental and institutional committees and perform other duties as assigned.
 

MINIMUM QUALIFICATIONS:
 

  • PhD, MD, or MD/PhD with board certification or board eligibility through the American Board of Medical Genetics and Genomics (ABMGG) in Molecular Genetics and Genomics (MGG), Cytogenetics and Genomics (CGG), or Laboratory Genetics and Genomics (LGG), or through Molecular Genetic Pathology (MGP).
     

    PREFERRED QUALIFICATIONS:
     

  • Hands-on experience with a wide range of molecular and cytogenetic laboratory techniques.
     

SALARY:
Commensurate with experience. 
 

Equal Employment Opportunity

UTMB Health strives to provide equal opportunity employment without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, genetic information, disability, veteran status, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. As a Federal Contractor, UTMB Health takes affirmative action to hire and advance protected veterans and individuals with disabilities.

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