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Research Associate Protein Purification Jobs (NOW HIRING)

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Research Associate Protein Purification information

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How much do research associate protein purification jobs pay per hour?

As of Jul 17, 2026, the average hourly pay for research associate protein purification in the United States is $32.54, according to ZipRecruiter salary data. Most workers in this role earn between $26.20 and $37.02 per hour, depending on experience, location, and employer.

What are some common challenges faced by Research Associates specializing in protein purification, and how can they be addressed?

Research Associates in protein purification often encounter challenges such as protein instability, low yield, and contamination during the purification process. Addressing these issues typically involves optimizing buffer conditions, adjusting purification protocols, and troubleshooting equipment. Collaboration with experienced colleagues and regular communication with other lab teams, such as molecular biology or analytical groups, also plays a key role in overcoming technical obstacles and ensuring high-quality results. Staying current with new purification technologies and best practices can further help mitigate common problems in this role.

What are the key skills and qualifications needed to thrive as a Research Associate in Protein Purification, and why are they important?

To thrive as a Research Associate in Protein Purification, you need a strong background in biochemistry or related fields, experience with protein expression and purification techniques, and typically a bachelor's or master's degree in the life sciences. Familiarity with chromatography systems (e.g., FPLC, HPLC), SDS-PAGE analysis, and laboratory information management systems (LIMS) is often required. Attention to detail, problem-solving skills, and the ability to work collaboratively are essential soft skills in this role. These skills and qualities ensure accurate experimental results, efficient workflow, and successful advancement of research projects.

What does a Research Associate in Protein Purification do?

A Research Associate in Protein Purification is responsible for isolating and purifying proteins from various biological sources using techniques such as chromatography, filtration, and centrifugation. They often work in laboratories, supporting scientific research and development projects by preparing high-quality protein samples for analysis or further experimentation. Their role may also include optimizing purification protocols, maintaining detailed laboratory records, and troubleshooting technical issues. This position is vital in biotech, pharmaceutical, and academic research settings where protein studies are essential.

What is the difference between Research Associate Protein Purification vs Research Associate Cell Culture?

AspectResearch Associate Protein PurificationResearch Associate Cell Culture
Required SkillsProtein purification techniques, chromatography, protein analysisCell culture, aseptic techniques, media preparation
Work EnvironmentLaboratories focused on biochemistry and protein analysisCell biology labs, tissue culture facilities
Common EmployerBiotech, pharmaceutical, research institutionsBiotech, pharmaceutical, research institutions

Research Associate Protein Purification and Research Associate Cell Culture roles share similar educational backgrounds and work environments but focus on different technical skills. Protein purification involves isolating and analyzing proteins, while cell culture emphasizes growing and maintaining cells. Both roles are essential in biotech and research settings, often overlapping in industry usage.

More about Research Associate Protein Purification jobs
What cities are hiring for Research Associate Protein Purification jobs? Cities with the most Research Associate Protein Purification job openings:
What states have the most Research Associate Protein Purification jobs? States with the most job openings for Research Associate Protein Purification jobs include:
Infographic showing various Research Associate Protein Purification job openings in the United States as of July 2026, with employment types broken down into 1% As Needed, 67% Full Time, 30% Part Time, 1% Temporary, and 1% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $67,685 per year, or $32.5 per hour.
Research Associate, Protein Chemistry & Bioconjugation (6 MONTH CONTRACT)

Research Associate, Protein Chemistry & Bioconjugation (6 MONTH CONTRACT)

Ring Therapeutics

Cambridge, MA

Other

Posted yesterday


Job description

6 MONTH CONTRACT --- ONSITE IN CAMBRIDGE, MACompany Summary

Ring Therapeutics Inc. is a privately held, early-stage biotechnology company pioneering a new field of targeted medicines by exploiting naturally occurring commensal viruses. Ring Therapeutics is leveraging this versatile technology to develop a broad pipeline of novel, targeted medicines for diseases with high unmet medical need.

Ring Therapeutics was founded in Flagship Pioneering's venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines (NASDAQ: GENB) were conceived and created. Since Flagship's founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures resulting in more than 500 issued patents and more than 50 clinical trials for novel therapeutic agents.

Position Summary

We are seeking a motivated and detail-oriented Research Associate to join our Protein Chemistry & Bioconjugation team. This is a hands-on bench role focused on supporting the production, modification, and characterization of antibodies, proteins, and bioconjugates that underpin our targeted therapeutic programs.

The ideal candidate has a solid foundation in standard protein workflows and bioconjugation chemistry and can generate high-quality, decision-driving data to advance platform development. Experience with or exposure to ADC or other biologics research and development is particularly desirable. This is a highly collaborative, hands-on role requiring scientific independence and a strong focus on delivering well-characterized, high-quality protein and conjugate inputs to enable downstream assay development and candidate selection.

Key ResponsibilitiesAntibody & Protein Conjugation
  • Execute common bioconjugation reactions.
  • Prepare and characterize antibody- and protein-conjugated constructs (e.g., fluorophore labeling and payload attachment).
  • Perform post-conjugation purification techniques including desalting columns and TFF.
Protein Processing & Characterization
  • Perform standard protein analytics and concentration measurements
  • Prepare formulation buffers and working reagents
  • Conduct buffer exchange and protein concentration
Lab Operations & Collaboration
  • Maintain accurate experimental records and SOPs in an electronic lab notebook (ELN)
  • Ensure proper inventory management of reagents, consumables, and protein stocks
  • Present data clearly and provide actionable recommendations to project teams
  • Collaborate cross-functionally with targeting, protein engineering, analytical, and translational teams to ensure materials align with program needs
Required Qualifications
  • S. or M.S. in Biochemistry, Bioengineering, Chemistry, or a related field
  • 1-3+ years of hands-on laboratory experience in a biotech, pharma, or academic research setting
  • Demonstrated proficiency in standard protein workflows:
  • Protein concentration measurement (UV-Vis spectroscopy, BCA, Bradford)
  • Protein characterization techniques (SDS-PAGE, DLS)
  • Buffer preparation and formulation
  • Buffer exchange via dialysis
  • Hands-on experience with at least one bioconjugation chemistry approach (e.g., NHS ester, maleimide, click chemistry)
  • Strong attention to detail, excellent organizational skills, and rigorous documentation habits
  • Ability to work independently and collaboratively in a fast-paced research environment
Preferred Qualifications
  • Experience with antibody-drug conjugates (ADCs)
  • Familiarity with TFF systems including Pulse TFF
  • Experience with SEC-HPLC or analytical HPLC for purity/conjugation analysis
  • Experience with protein purification workflows including IMAC, SEC, and ion exchange chromatography
  • Experience with data analysis tools (GraphPad Prism, imageJ)
Key Competencies
  • Hands-on proficiency in bench-scale protein chemistry and bioconjugation
  • Methodical approach to experimental execution and troubleshooting
  • High standards for data quality, reproducibility, and documentation
  • Clear, concise communication of technical results to cross-functional team members
  • Proactive, team-oriented mindset with flexibility to support evolving project priorities