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Research Associate Downstream Process Development Jobs in Connecticut

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Research Scientist

Stamford, CT · On-site

$85K - $140K/yr

Understanding of application of AI / Machine Learning tools to new product and process development ... associates. Our solutions contribute to safer, cleaner, and more sustainable products found in ...

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Research Associate Downstream Process Development information

What is a research associate downstream process development?

A Research Associate in Downstream Process Development works within biotechnology or pharmaceutical companies to optimize and scale up the purification and recovery of biological products, such as proteins or antibodies, after initial production. They focus on processes like filtration, chromatography, and centrifugation to ensure product quality and yield. These professionals design experiments, analyze data, and support the transfer of processes from laboratory scale to manufacturing. Their work is crucial for developing efficient, reproducible, and regulatory-compliant methods for producing biopharmaceuticals.

What are the key skills and qualifications needed to thrive as a research associate in downstream process development?

To thrive as a Research Associate in Downstream Process Development, you need a solid background in biochemistry, molecular biology, or chemical engineering, often demonstrated by a bachelor's or master's degree in a related field. Familiarity with chromatography systems (such as AKTA), filtration technologies, and Good Manufacturing Practice (GMP) standards, along with data analysis software, is typically required. Strong problem-solving skills, attention to detail, and effective teamwork and communication abilities help individuals excel in this role. These competencies are crucial for ensuring efficient, scalable purification processes and maintaining product quality in biopharmaceutical development.

What are the typical challenges faced by a research associate in downstream process development, and how can they be addressed?

A Research Associate in Downstream Process Development often encounters challenges such as optimizing purification processes for new biologics, troubleshooting equipment issues, and ensuring scalability from laboratory to production scale. Effective communication with cross-functional teams, such as upstream scientists and analytical specialists, is essential to resolve issues quickly. Staying current with new purification technologies and maintaining meticulous documentation can also help address these challenges and support successful process development.

What is the difference between Research Associate Downstream Process Development vs Research Associate Upstream Process Development?

AspectResearch Associate Downstream Process DevelopmentResearch Associate Upstream Process Development
Primary FocusPurification, filtration, chromatography of bioproductsCell culture, media optimization, bioreactor operation
Skills & CertificationsProtein purification, chromatography techniques, GMP complianceCell culture, aseptic techniques, bioreactor handling
Work EnvironmentLaboratory, manufacturing, quality controlLaboratory, bioprocessing facilities
Industry UsageBiopharmaceutical manufacturing, biotech researchBiopharmaceutical development, biotech research

While both roles support bioprocess development, Research Associate Downstream Process Development focuses on purification and filtration of bioproducts, whereas Research Associate Upstream Process Development emphasizes cell culture and bioreactor processes. Understanding these differences helps candidates align their skills with the appropriate role in biopharmaceutical production.

Infographic showing various Research Associate Downstream Process Development job openings in Connecticut as of September 2026, with employment types broken down into 67% Full Time, and 33% Contract. Highlights an 100% In-person job distribution.

Field Applications Scientist - Purification (Chromatography & Resins)

Groton, CT

Thermo Fisher Scientific
Biotechnology Research and Development • 10K+ employees

Full-time

Posted 20 days ago


Thermo Fisher Scientific rating

7.8

Company rating: 7.8 out of 10

Based on 430 frontline employees who took The Breakroom Quiz

171st of 547 rated manufacturers


Job description

Work Schedule

Standard (Mon-Fri)

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Office

Job Description

Position Summary

The Field Applications Scientist (FAS) – Purification is part of the BioProduction Group (BPG) and serves as a technical expert in downstream purification, with a primary focus on chromatography and purification resins.

Working closely with biopharmaceutical customers, the FAS supports the evaluation, selection, and application of chromatography resins for existing purification processes and new molecule development. The role engages directly with scientists and engineers to understand their purification challenges, recommend appropriate solutions, and scientifically demonstrate and validate product performance through technical discussions, data analysis, and experimental evaluation.

A key purpose of this role is to demonstrate the technical value and performance of our chromatography and resin portfolio and translate that technical value into customer adoption and business opportunities. The FAS works closely with Sales and other cross-functional teams, providing the scientific expertise and technical credibility required to support customer decision-making.

The FAS also provides post-sales technical support, addresses product and application-related inquiries, troubleshoots technical issues, and delivers technical training to customers and internal teams.

Key Responsibilities

  • Serve as a subject matter expert in downstream purification, with a primary focus on chromatography processes and purification resins.
  • Engage directly with customer scientists and engineers to understand existing purification processes, new molecule requirements, process challenges, and technical needs.
  • Recommend appropriate chromatography resins and solutions based on customer process requirements and scientific understanding of the target molecule and purification process.
  • Provide scientific and technical explanations of product characteristics, performance, and application benefits to demonstrate the value of our chromatography and resin portfolio.
  • Design, support, and execute technical evaluations and experiments to validate product performance and demonstrate suitability for customer applications.
  • Analyze and interpret experimental results and communicate technical conclusions and recommendations clearly to customers and internal stakeholders.
  • Partner with Sales teams to support technical evaluations and customer decision-making, helping convert successful technical engagements into product adoption and commercial opportunities.
  • Provide pre- and post-sales application support, including troubleshooting of chromatography processes, resin performance, and product-related technical issues.
  • Respond to customer technical inquiries and work with relevant internal teams to resolve complex application or product performance issues.
  • Develop and deliver technical presentations, seminars, and training programs for customers on chromatography, purification processes, resin technologies, and product applications.
  • Provide technical training and application knowledge to Sales and other internal teams to strengthen organizational capability in chromatography and resin technologies.
  • Capture customer feedback, unmet technical needs, competitive insights, and new application opportunities, and communicate them to Sales, Product Management, R&D, and other relevant teams.
  • Maintain and continuously develop strong technical knowledge of chromatography principles, downstream purification processes, resin technologies, and the company's purification product portfolio.

Qualifications

  • Master's degree or higher in Biochemistry, Biotechnology, Chemical Engineering, Biochemical Engineering, Life Sciences, or a related scientific or engineering discipline preferred.
  • Minimum 4-7 years of hands-on experience as a scientist or engineer in biopharmaceutical downstream purification, with significant experience in chromatography process development and purification resins.
  • Strong scientific and practical understanding of chromatography principles and resin technologies used in biopharmaceutical purification.
  • Hands-on experience in chromatography process development, including resin selection and screening, process optimization, experimental design, data analysis, and troubleshooting.
  • Ability to understand customer purification processes and molecule-specific challenges and translate them into appropriate chromatography and resin solutions.
  • Strong scientific problem-solving skills with the ability to design technical approaches, interpret experimental results, and make data-driven recommendations.
  • Strong customer-facing communication skills with the ability to discuss complex scientific and technical topics with scientists, engineers, and other technical stakeholders.
  • Strong presentation and training skills, with the ability to communicate technical concepts effectively to both customers and internal teams.
  • Ability to work independently while collaborating effectively with Sales, Product Management, R&D, and regional/global technical teams.
  • Customer-focused mindset with the ability to build trusted technical relationships and support long-term customer engagement.
  • Fluent Korean and professional proficiency in English for technical discussions, presentations, meetings, and written communication.
  • Willingness to travel regularly for customer visits, technical evaluations, training, and other field activities.

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