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Research Associate Assay Development Jobs in Seattle, WA

Integrated Resources INC

Research Associate

Seattle, WA · On-site

Cytokine detection assay and MSD and experience in Whole blood and normal cell is good Candidate will perform Reporter assay- Run small molecules through those and interpreting. Work with PBMC's and ...

Uw

Research Scientist/Engr 1

Seattle, WA · On-site

$58K/yr

In vitro functional assay development and execution - 25% Develop and run cell-free transcription ... UAW Research About the UW Working at the University of Washington provides a unique opportunity to ...

Vrtx

Senior Director, Biomarkers (Immunology)

Seattle, WA · On-site

$216K - $325K/yr

The incumbent is an expert in the field of assay development and validation and works with a team ... Experience with autoimmune disease research or immunology therapeutic pipelines. * Ability to ...

Omeros

Research Associate I

Seattle, WA

This individual will be part of a growing team responsible for the development, execution, and data ... The Research Associate will develop, execute, and manage methods used for clinical and commercial ...

Omeros Corp.

Research Associate I

Seattle, WA · On-site

This individual will be part of a growing team responsible for the development, execution, and data ... The Research Associate will develop, execute, and manage methods used for clinical and commercial ...

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Research Associate Assay Development information

See Seattle, WA salary details

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$37

$53

How much do research associate assay development jobs pay per hour?

As of Sep 5, 2026, the average hourly pay for research associate assay development in Seattle, WA is $37.03, according to ZipRecruiter salary data. Most workers in this role earn between $29.81 and $42.12 per hour, depending on experience, location, and employer.

What does a research associate in assay development do?

A Research Associate in Assay Development is responsible for designing, developing, and optimizing laboratory assays to detect or measure biological substances. They typically work in biotechnology or pharmaceutical companies, supporting research and development projects by ensuring assays are robust, reliable, and reproducible. Their duties may include preparing samples, analyzing data, troubleshooting protocols, and collaborating with other scientists to improve experimental workflows. This role requires strong analytical skills and a background in biology, chemistry, or a related field.

What are the key skills and qualifications needed to thrive as a research associate in assay development?

To thrive as a Research Associate in Assay Development, you need a solid background in biochemistry, molecular biology, or a related field, often with a bachelor’s or master’s degree. Familiarity with laboratory techniques such as ELISA, PCR, and use of analytical instruments, along with experience using data analysis software, is typically required. Attention to detail, critical thinking, and strong organizational and communication skills help you excel in experimental design and collaborative scientific environments. These skills ensure reliable assay results, efficient workflow, and meaningful contributions to research and product development.

What are some typical challenges faced by a research associate in assay development, and how can they be addressed?

Research Associates in Assay Development often encounter challenges such as troubleshooting experimental variability, optimizing assay conditions, and managing tight project timelines. These issues can be addressed by maintaining meticulous documentation, collaborating closely with senior scientists and cross-functional teams, and staying current with the latest assay technologies and protocols. Seeking feedback from peers and participating in regular team meetings also helps in overcoming technical hurdles and ensuring that project goals are met efficiently.

Do I need a PhD to be a research associate assay development?

A research associate in assay development typically does not require a PhD; a bachelor's or master's degree in a relevant field such as biology, chemistry, or biochemistry is often sufficient. Relevant skills include laboratory techniques, data analysis, and familiarity with assay platforms. Advanced roles or research-focused positions may prefer or require a PhD.

What cities near Seattle, WA are hiring for Research Associate Assay Development jobs?

Cities near Seattle, WA with the most Research Associate Assay Development job openings:

Research Associate Assay Development jobs near you
Infographic showing various Research Associate Assay Development job openings in Seattle, WA as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 14% Part Time, and 3% Contract. Highlights an 90% Physical, 3% Hybrid, and 7% Remote job distribution, with an average salary of $77,028 per year, or $37 per hour.

Scientist/Senior Scientist, Companion Diagnostics (CDx) - IHC Development

Systimmune

Redmond, WA • On-site

$90K - $140K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 23 days ago

Job description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
 
We are seeking a Scientist or Senior Scientist to lead and support immunohistochemistry (IHC) assay development for companion diagnostic (CDx) kits supporting oncology drug development. This role is responsible for end-to-end IHC assay development, including antibody selection, assay optimization, analytical validation, and clinical trial implementation, with a clear development path from RUO/LDT to IVD CDx commercialization.
The ideal candidate has strong expertise in pathology, IHC assay development, and CDx regulatory expectations, and can work effectively across R&D, clinical, regulatory, QA, and external CROs and central laboratories.
Key Responsibilities
IHC Assay & CDx Development
  • Lead development of IHC-based CDx assays, from biomarker discovery through assay optimization and validation.
  • Select and evaluate primary antibodies, detection systems, and staining platforms (e.g., Ventana, Dako, Leica).
  • Optimize assay parameters, including epitope retrieval, antibody dilution, detection chemistry, and staining conditions.
  • Establish scoring algorithms, cut-off strategies, and interpretation guidelines in collaboration with pathologists.
  • Support biomarker strategies for patient selection and stratification in clinical trials.

Analytical Validation & Performance
  • Design and oversee analytical performance studies, including:
    • Sensitivity and specificity
    • Precision and reproducibility (intra-run, inter-run, inter-site)
    • Accuracy and robustness
    • Linearity and limit of detection, where applicable
  • Prepare, review, and approve validation protocols, reports, and SOPs in alignment with CDx expectations.

Clinical Trial & Central Lab Support
  • Support implementation of IHC assays in clinical trials, including:
    • Central laboratory qualification and oversight
    • Pathologist training and alignment
    • Slide logistics, staining consistency, and scoring harmonization
  • Collaborate with clinical teams on sample strategy, feasibility studies, and biomarker cut-off justification.
  • Regulatory & Quality Collaboration
  • Work closely with Regulatory Affairs and Quality Assurance to ensure compliance with:
    • FDA CDx guidance (US)
    • NMPA/CDE requirements (China), where applicable
    • IVDR (EU), as relevant
  • Support preparation of regulatory documentation, including:
    • IDE/IND biomarker sections
    • CDx bridging strategies (RUO/LDT → IVD)
    • Analytical and clinical performance summaries
  • Ensure assay development aligns with QMS requirements, design controls, and document traceability.
Cross-Functional & External Collaboration
  • Serve as a technical subject-matter expert, interacting with:
    • CROs, central laboratories, and IVD partners
    • Antibody vendors and staining platform providers
  • Provide scientific input to project teams, governance meetings, and external collaborations.
  • Mentor junior scientists and contribute to team capability building, as appropriate.

Qualifications
Education
  • PhD in Pathology, Molecular Biology, Immunology, Oncology, or a related field
  • MS or BS with significant CDx or IVD industry experience may be considered

Experience
  • 3–5+ years of hands-on experience in IHC assay development, preferably in a CDx or IVD setting
  • Direct experience supporting oncology biomarkers and clinical trials
  • Experience across the CDx development lifecycle (RUO/LDT through IVD readiness)
  • Strong understanding of IHC scoring methodologies (e.g., TPS, H-score, CPS)
  • Familiarity with analytical validation and regulatory expectations for CDx
  • Demonstrated ability to work effectively in cross-functional teams

Soft Skills
  • Strong scientific rigor with excellent documentation and data interpretation skills
  • Ability to operate in a fast-paced, matrix environment
  • Clear and effective communication with both technical and non-technical stakeholders
  • Experience working with global teams is a plus

Preferred Qualifications
  • Prior experience with late-stage or FDA-approved CDx programs
  • Experience developing and justifying biomarker cut-off strategies
  • Familiarity with NSCLC, GI cancers, or other solid tumors
  • Experience interacting with health authorities or supporting regulatory meetings

Why Join Us
  • Opportunity to shape next-generation CDx programs linked to innovative oncology therapeutics
  • High-visibility role with direct impact on patient selection and drug approval
  • Collaborative environment bridging pathology, translational science, and regulatory strategy

Compensation and Benefits:
The expected base salary range for this position is $90,000 - $140,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, level of the position, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.
 
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
 
We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.
 
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.

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