Remote Python Startup Jobs in Colorado (NOW HIRING)

Location: Boulder, CO · Full-Time · Remote

The scientists and engineers building our MRD cancer detection platform move fast. The infrastructure they rely on needs to be faster, more reliable, and ready for the scrutiny of a regulated clinical environment. At Foresight Diagnostics - now part of Natera - we’re looking for a DevOps Engineer who can build and own the delivery systems that let our teams ship with confidence. If you want your infrastructure work to directly enable earlier cancer detection for real patients, this is the role.

ABOUT FORESIGHT DIAGNOSTICS

Foresight Diagnostics is a molecular diagnostics company pioneering non-invasive cancer detection through highly sensitive, cell-free DNA-based liquid biopsy technologies. Our proprietary methods - originally developed at Stanford University - are designed to detect smaller tumors earlier and enable more personalized treatment strategies for patients with cancer.

We sit at the intersection of molecular biology, bioinformatics, and next-generation sequencing (NGS), and we translate rigorous science into clinically meaningful solutions. Following our acquisition by Natera, we now combine the agility of a mission-driven startup with the scale and resources of a global leader in cell-free DNA testing. It’s an exciting moment to join us.

Headquartered in Boulder, Colorado, our team operates in a high accountability, collaborative environment where quality and continuous improvement aren’t just values - they’re how we work every day.

WHY THIS ROLE EXISTS

Our bioinformatics pipelines, software systems, and diagnostic infrastructure are growing in complexity and scale. Development teams need fast, reliable, secure delivery workflows. Bioinformatics scientists need reproducible, well-governed compute environments. And as a regulated clinical diagnostics company, we need it to be auditable and compliant.

This is a greenfield opportunity to shape how software gets built and deployed at Foresight Dx - designing CI/CD architecture, driving automation across GCP and AWS, and becoming the infrastructure partner our engineering and science teams depend on.

WHAT YOU’LL DO

You’ll work primarily with GitHub Actions, Terraform, Docker, and Kubernetes across GCP and AWS environments - collaborating day-to-day with software engineers, bioinformatics scientists, and operations teams. In practice, this means:

• Designing, building and maintaining CI/CD pipelines using GitHub Actions to automate builds, testing, and deployment across development and production environments.

• Implementing infrastructure-as-code solutions with Terraform to support repeatable, version-controlled, and auditable infrastructure deployments.

• Automating deployment and configuration of applications, bioinformatics pipelines, and supporting services across both GCP and AWS.

• Building and maintaining automation scripts in Python and Shell/Bash to reduce manual operations, improve deployment reliability, and increase developer velocity.

• Managing containerized applications using Docker, Kubernetes, Google Cloud Run, and AWS container services.

• Configuring and maintaining monitoring, logging, and altering solutions to provide full visibility into application and pipeline health.

• Implementing security controls across CI/CD pipelines - including secrets management, access controls, and vulnerability scanning - with a regulated-environment mindset.

• Managing configuration management for application environments and bioinformatics workstations.

• Creating clear, comprehensive documentation for deployment processes, runbooks, and troubleshooting guides that support regulatory compliance requirements.

• Driving continuous improvement initiatives to reduce deployment friction, improve build times, and make developers more productive.

• Mentoring and providing technical guidance to development teams on DevOps best practices, cloud-native patterns, and tooling.

WHAT YOU’LL BRING

Required

• 5-10 years of experience in DevOps, platform engineering, or software engineering with a strong automation focus.

• Proven expertise building and maintaining CI/CD pipelines - GitHub Actions experience strongly preferred; GitLab CI or Jenkins also relevant.

• Strong hands-on experience with GCP and AWS, including deploying and managing production workloads in both environments.

• Proficiency with Terraform for infrastructure-as-code automation and provisioning.

• Solid experience with containerization and orchestration - Docker and Kubernetes are core to this role.

• Strong scripting skills in Python and Shell/Bash; you’re comfortable writing automation from scratch, not just adapting templates.

• Experience with configuration management tools such as Ansible, Chef, or Puppet.

• Solid understanding of software development lifecycle, Git Version control workflows, and branching strategies.

• Experience implementing security best practices in CI/CD pipelines and cloud environments.

• Strong written communication skills and a track record of producing clear, useful process documentation.

• A pragmatic, learner’s mindset - you balance quick wins with thoughtful long-term architecture decisions.

Preferred

• Experienced in regulatory industry - FDA, clinical diagnostics, healthcare - with exposure to validation and compliance documentation requirements.

• Background in software development or engineering with understanding of application architecture.

• Familiarity with bioinformatics workflows, NGS pipelines, or computational biology environments.

• Experience with observability platforms such as Prometheus, Grafana, Datadog, or New Relic.

• Knowledge of GitOps practices and declarative deployment patterns.

• Cloud FinOps experience or cost optimization work in multi-cloud environments.

• Contributions to open-source DevOps tools or automation projects.

WHY JOIN US

This is a rare opportunity to do high-craft infrastructure work inside a mission-driven company - where your pipelines directly enable the science that catches cancer earlier for real patients. You’ll have real ownership, minimal bureaucracy, and the backing of both a focused technical team and Natera’s enterprise-scale resources.

COMPENSATION, BENEFITS & EQUAL OPPORTUNITY

This role offers a competitive annual base compensation of $111,500.00 - $139,400.00 commensurate with experience, equity participation, and a comprehensive benefits package including:

• Medical, dental, and vision

• Flexible PTO and paid holidays

• Parental leave

• 401(k) with company match

You will be working on interesting problems with extremely high impact. We promote the professional development of our teams and encourage upward mobility within the company for high performing employees. Foresight Diagnostics is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Ready to make an impact in cancer diagnostics?

Apply below - we’d love to hear from you.