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Remote Python Sql Jobs in Massachusetts (NOW HIRING)

eClinical Solutions

Principal Software Engineer

Mansfield, MA · On-site +1

$142K - $191K/yr

NET- and Python-based systems * Designing and implementing AI-assisted workflows , copilots, or ... Strong SQL expertise (Microsoft SQL Server preferred), including performance tuning * Experience ...

eClinical Solutions

Principal Software Engineer

Mansfield, MA · On-site +1

$142K - $191K/yr

NET- and Python-based systems * Designing and implementing AI-assisted workflows , copilots, or ... Strong SQL expertise (Microsoft SQL Server preferred), including performance tuning * Experience ...

eClinical Solutions

Principal Software Engineer

Mansfield, MA · On-site +1

$142K - $191K/yr

NET- and Python-based systems * Designing and implementing AI-assisted workflows , copilots, or ... Strong SQL expertise (Microsoft SQL Server preferred), including performance tuning * Experience ...

eClinical Solutions

Principal Software Engineer

Mansfield, MA · On-site +1

$142K - $191K/yr

NET- and Python-based systems * Designing and implementing AI-assisted workflows , copilots, or ... Strong SQL expertise (Microsoft SQL Server preferred), including performance tuning * Experience ...

WEX

Senior Software Engineer - Semantic Data Lake

Boston, MA · Remote

$133K - $175K/yr

This is a remote position; however, the candidate must reside within 30 miles of one of the ... Write production-quality, testable code in SQL and Python (or equivalent)-delivering performant and ...

Kobie Marketing

AI Engineer

Boston, MA · Remote

Join a National Top Workplace Named a Top Workplace in the USA and Top Remote Workplace, Kobie is ... Build agent harnesses in Python using LangChain and LangGraph, including tool-calling, structured ...

The Phia Group

Data Engineer (Remote)

Canton, MA · On-site +1

$121K - $145K/yr

Solid programming skills in advanced SQL, Python, or other programming languages for data processing and automation Experience supporting or working with AI/ML workflows, including: * Data ...

The Phia Group

Data Engineer (Remote)

Louisville, KY · On-site +1

$110K - $132K/yr

Solid programming skills in advanced SQL, Python, or other programming languages for data processing and automation Experience supporting or working with AI/ML workflows, including: * Data ...

ezCater, Inc

Senior Analyst, Product (Remote)

Boston, MA · On-site +1

$120K - $146K/yr

Strong SQL skills for data manipulation and analysis, coupled with experience in statistical ... modeling (Python preferred) * Proficiency in site analytics and experimental test design

ICONSTAFF

Backend Engineer/FullStack

Cambridge, MA · On-site +1

$140K - $220K/yr

Production experience with Python and SQL * Familiarity with Git and CI/CD workflows * Excellent ... Remote work stipend * Generous PTO Next Steps If you're interested in working on challenging ...

Knak Digital

AI Engineer

Becket, MA · Remote

Remote (US only) Must be authorized to work in the US and obtain a Public Trust Clearance . A small ... Proficiency in both Python and JavaScript * Hands-on experience designing or building agentic ...

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Remote Python Sql information

What are some common challenges faced by Remote Python & SQL Developers, and how can they be addressed?

Remote Python & SQL Developers often face challenges such as effective communication with distributed teams, managing overlapping project priorities, and ensuring data security when accessing databases remotely. To address these, it's crucial to establish clear communication routines (like daily stand-ups), use collaborative tools (such as Slack or Jira), and strictly follow company protocols for secure database access. Proactively seeking feedback and documenting code also help maintain project alignment and code quality within a remote environment.

What is a Remote Python SQL job?

A Remote Python SQL job involves working with databases and backend systems using the Python programming language and SQL (Structured Query Language) while working from a location outside of a traditional office. Professionals in this role typically write code to query, manipulate, and analyze data stored in databases, automate data workflows, and build data-driven applications. Remote arrangements allow these tasks to be completed from anywhere with a stable internet connection, offering flexibility while still requiring strong technical and communication skills.

What is the difference between Remote Python Sql vs Remote Data Analyst?

AspectRemote Python SqlRemote Data Analyst
Required SkillsPython, SQL, data manipulationData visualization, SQL, statistical analysis
Work EnvironmentRemote, programming-focusedRemote, analysis and reporting
Industry UsageTech, finance, data-driven companiesBusiness, marketing, finance
CertificationsPython, SQL certificationsData analysis, Excel, Tableau certifications

Remote Python Sql roles focus on programming, data extraction, and database management, while Remote Data Analyst positions emphasize interpreting data, creating reports, and visualizations. Both roles often require SQL skills and can be found in similar industries, but they serve different functions within data teams.

What are the key skills and qualifications needed to thrive as a Remote Python SQL Developer, and why are they important?

To thrive as a Remote Python SQL Developer, you need strong proficiency in Python programming and SQL database management, typically backed by a degree in computer science or related experience. Familiarity with tools like PostgreSQL, MySQL, version control systems (e.g., Git), and cloud platforms is commonly required, along with any relevant certifications. Excellent problem-solving, self-motivation, and effective remote communication skills set standout professionals apart in this role. These skills are crucial for efficiently building and maintaining robust data-driven applications while collaborating seamlessly in distributed teams.
What are the most commonly searched types of Python Sql jobs in Massachusetts? The most popular types of Python Sql jobs in Massachusetts are:
What are popular job titles related to Remote Python Sql jobs in Massachusetts? For Remote Python Sql jobs in Massachusetts, the most frequently searched job titles are:
What job categories do people searching Remote Python Sql jobs in Massachusetts look for? The top searched job categories for Remote Python Sql jobs in Massachusetts are:
What cities in Massachusetts are hiring for Remote Python Sql jobs? Cities in Massachusetts with the most Remote Python Sql job openings:
Remote Python Sql jobs near you
Infographic showing various Remote Python Sql job openings in Massachusetts as of July 2026, with employment types broken down into 48% Full Time, and 52% Contract. Highlights an 100% Remote job distribution.
Principal Software Engineer

Principal Software Engineer

eClinical Solutions

Mansfield, MA • On-site, Remote

$142K - $191K/yr

Full-time

Re-posted 3 days ago

Job description

About eClinical Solutions
eClinical Solutions is transforming clinical development with elluminate®, our Clinical Data Cloud, helping life sciences organizations unify, analyze, and unlock the value of their data faster than ever before. By combining a modern cloud platform with expert data services, we empower smarter decisions across the clinical trial lifecycle-accelerating innovation that ultimately improves patient outcomes.
Our engineering teams build enterprise-grade, revenue-generating products at the intersection of cloud, data, analytics, and emerging AI technologies. If you're excited about building sophisticated software that makes a real-world impact on healthcare, this is the place to do it.
You will make an impact:
As a Principal Full Stack Software Engineer, you will be a technical leader within the elluminate Product Development team. You'll help design and build the core services and user experiences of a next-generation clinical data and analytics platform-while influencing architecture, engineering standards, and technical direction.
This role is ideal for an experienced engineer who enjoys hands-on development, mentoring others, and bringing modern capabilities-including AI-assisted and agentic workflows-into production-grade systems.
Your day to day:
  • Design, develop, test, and deploy scalable, secure, and highly interactive web applications
  • Own and evolve core platform modules, from concept through release and support
  • Influence application and system architecture with a focus on performance, reliability, security, and maintainability
  • Lead by example through clean, well-tested code, thoughtful design reviews, and pragmatic technical decisions
  • Collaborate closely with Product Management, QA, and other engineers throughout the SDLC
  • Provide technical mentorship and guidance to other engineers on the team
  • Diagnoses and resolves complex production issues across distributed systems
  • Ensure solutions meet eClinical Solutions quality standards and applicable industry regulations
  • Contribute to technical documentation including design specs, acceptance criteria, and release notes

AI & Modern Engineering Focus
We're actively incorporating AI-powered capabilities into our platform, and you'll help shape how this is done responsibly and effectively in an enterprise environment. This includes:
  • Integrating LLMs and AI services into .NET- and Python-based systems
  • Designing and implementing AI-assisted workflows, copilots, or intelligent automation features
  • Working with agentic AI patterns (e.g., task orchestration, tool-using agents, workflow automation)
  • Applying prompt engineering, evaluation techniques, and guardrails to ensure reliability and compliance
  • Collaborating with data and platform teams to operationalize AI-not just prototype it

Deep ML expertise is not required-we're looking for strong engineers who understand how to apply AI capabilities in real products.
Take the first step toward your dream career. Here is what we are looking for in this role.
Qualifications:
  • Bachelor's or Master's degree in Computer Science or equivalent practical experience
  • 10+ years in software design and development using the Microsoft technology stack preferred
  • Expert-level proficiency in C#, .NET, and ASP.NET (MVC/Web APIs)
  • Strong experience building full-stack web applications (Angular, TypeScript, HTML, CSS)
  • Solid understanding of software design principles, patterns, and best practices
  • Experience across the full Software Development Lifecycle (Agile preferred)
  • Proven ability to work independently while collaborating effectively in a fast-paced environment
  • Excellent communication, documentation, and technical leadership skills

AI & Platform Experience
  • Hands-on experience integrating LLM-based services (e.g., OpenAI, Azure OpenAI, or similar) into applications
  • Experience using Python and/or .NET alongside AI/LLM workflows
  • Familiarity with agent-based or workflow-driven AI architectures is a strong plus
  • Understanding of secure and responsible AI usage in enterprise systems

Nice to Have
  • Strong SQL expertise (Microsoft SQL Server preferred), including performance tuning
  • Experience with microservices, distributed systems, and cloud platforms (AWS preferred)
  • Secure development experience, including awareness of common vulnerabilities and mitigations
  • Experience with clinical trial data, life sciences, or regulated SaaS environments
  • Experience building data visualizations or analytics-driven user experiences

Accelerate your skills and career within a fast-growing company while impacting the future of healthcare. We have shared our story, now we look forward to learning yours!
eClinical is a winner of the 2025 Top Workplaces USA Award for Remote Work! We have also received numerous Top Workplaces Culture Excellence Awards celebrating our exceptional company vision, values, and work-life balance. See all the details here: https://topworkplaces.com/company/eclinical-solutions/
eClinical Solutions is a people first organization. Our inclusive culture values the contribution that diversity brings to our business. We celebrate individual experiences that connect us and that inspire innovation in our community. Our team seeks out opportunities to learn, grow and continuously improve. Bring your authentic self, you are welcome here!
We are proud to be an equal opportunity employer that values diversity. Our management team is committed to the principle that employment decisions are based on qualifications, merit, culture fit and business need.
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Pay Range
US Pay Ranges
$152,000-$190,000 USD

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