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Remote Python Llm Jobs in Boston, MA (NOW HIRING)

Principal Software Engineer

Mansfield, MA ยท On-site +1

$142K - $191K/yr

Experience using Python and/or .NET alongside AI/LLM workflows * Familiarity with agent-based or ... for Remote Work! We have also received numerous Top Workplaces Culture Excellence Awards ...

Principal Software Engineer

Mansfield, MA ยท On-site +1

$142K - $191K/yr

Experience using Python and/or .NET alongside AI/LLM workflows * Familiarity with agent-based or ... for Remote Work! We have also received numerous Top Workplaces Culture Excellence Awards ...

Senior Machine Learning Engineer

Boston, MA ยท On-site +1

$113K - $155K/yr

One of the team's major focus areas is the Commerce and Support Assistant (CSA), an LLM-driven ... This role is currently open to remote work. Candidates must be located near one of our hub ...

Senior Machine Learning Engineer

Boston, MA ยท On-site +1

$133K - $175K/yr

Format data appropriately for the chosen LLM and training pipeline * Model Training & Fine-Tuning ... Proficiency in Python and relevant ML libraries (e.g., TensorFlow, PyTorch, Scikit-learn, Pandas ...

Senior Machine Learning Engineer

Boston, MA ยท On-site +1

$133K - $175K/yr

Format data appropriately for the chosen LLM and training pipeline * Model Training & Fine-Tuning ... Proficiency in Python and relevant ML libraries (e.g., TensorFlow, PyTorch, Scikit-learn, Pandas ...

Senior Machine Learning Engineer

Boston, MA ยท Remote

$125K - $165K/yr

Format data appropriately for the chosen LLM and training pipeline * Model Training & Fine-Tuning ... Proficiency in Python and relevant ML libraries (e.g., TensorFlow, PyTorch, Scikit-learn, Pandas ...

AI/ML Tech Lead / Architect

Boston, MA ยท On-site +1

$60 - $82.25/hr

... can work remote. This is the least preferred option. Type of Hire: Contract/ C2H - Contract ... Python in the context of Conversational AI. Design, build, and deploy machine learning models on ...

AI Automation Engineer -Remote

Brockton, MA ยท On-site +1

$202K - $234K/yr

Experience creating LLM-backed tools involving prompt engineering and automated evals * 5+ years of ... Python, React and JavaScript * Excellent debugging skills and the ability to manage multiple ...

AI Automation Engineer -Remote

Lowell, MA ยท On-site +1

$202K - $234K/yr

Experience creating LLM-backed tools involving prompt engineering and automated evals * 5+ years of ... Python, React and JavaScript * Excellent debugging skills and the ability to manage multiple ...

AI Automation Engineer -Remote

Babson Park, MA ยท On-site +1

$202K - $234K/yr

Experience creating LLM-backed tools involving prompt engineering and automated evals * 5+ years of ... Python, React and JavaScript * Excellent debugging skills and the ability to manage multiple ...

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Remote Python Llm information

See Boston, MA salary details

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How much do remote python llm jobs pay per hour?

As of Jun 18, 2026, the average hourly pay for remote python llm in Boston, MA is $63.69, according to ZipRecruiter salary data. Most workers in this role earn between $52.50 and $72.36 per hour, depending on experience, location, and employer.

What is a Remote Python LLM job?

A Remote Python LLM job typically involves working with large language models (LLMs) like GPT or similar AI technologies using the Python programming language, while operating remotely. Professionals in this role develop, fine-tune, and deploy machine learning models, especially those focused on natural language processing (NLP) tasks. Responsibilities may include building Python applications that integrate with LLMs, data preprocessing, and collaborating with teams across different locations. The remote aspect allows for flexible work arrangements and access to global opportunities.

What are some common collaboration methods used by Remote Python LLM engineers when working with cross-functional teams?

Remote Python LLM engineers frequently collaborate with data scientists, product managers, and other developers through virtual meetings, code reviews, and shared documentation platforms. Tools like Slack, GitHub, and Jira are often used to ensure smooth communication and project tracking, despite working across different time zones. Regular stand-ups and sprint planning sessions help align objectives and keep everyone updated on progress. Proactive communication and clear documentation are key to overcoming the challenges of remote, distributed teamwork in this role.

What are the key skills and qualifications needed to thrive as a Remote Python LLM Engineer, and why are they important?

To thrive as a Remote Python LLM Engineer, you need strong proficiency in Python programming, experience with large language models (LLMs), and a degree in computer science or a related field. Familiarity with machine learning frameworks (such as TensorFlow or PyTorch), cloud platforms, and version control systems like Git is typically required. Excellent problem-solving abilities, self-motivation, and effective communication are crucial soft skills for remote collaboration and troubleshooting. These skills ensure you can develop, deploy, and maintain advanced language models efficiently while working independently in distributed teams.
What are popular job titles related to Remote Python Llm jobs in Boston, MA? For Remote Python Llm jobs in Boston, MA, the most frequently searched job titles are:
What job categories do people searching Remote Python Llm jobs in Boston, MA look for? The top searched job categories for Remote Python Llm jobs in Boston, MA are:
What cities near Boston, MA are hiring for Remote Python Llm jobs? Cities near Boston, MA with the most Remote Python Llm job openings:
Principal Software Engineer

Principal Software Engineer

eClinical Solutions

Mansfield, MA โ€ข On-site, Remote

$142K - $191K/yr

Other

Posted 11 days ago


Job description

About eClinical Solutions

eClinical Solutions is transforming clinical development with elluminate, our Clinical Data Cloud, helping life sciences organizations unify, analyze, and unlock the value of their data faster than ever before. By combining a modern cloud platform with expert data services, we empower smarter decisions across the clinical trial lifecycle-accelerating innovation that ultimately improves patient outcomes.

Our engineering teams build enterprise-grade, revenue-generating products at the intersection of cloud, data, analytics, and emerging AI technologies. If you're excited about building sophisticated software that makes a real-world impact on healthcare, this is the place to do it.

You will make an impact:ย 

As a Principal Full Stack Software Engineer, you will be a technical leader within the elluminate Product Development team. You'll help design and build the core services and user experiences of a next-generation clinical data and analytics platform-while influencing architecture, engineering standards, and technical direction.

This role is ideal for an experienced engineer who enjoys hands-on development, mentoring others, and bringing modern capabilities-including AI-assisted and agentic workflows-into production-grade systems.

Your day to day:ย 

  • Design, develop, test, and deploy scalable, secure, and highly interactive web applications
  • Own and evolve core platform modules, from concept through release and support
  • Influence application and system architecture with a focus on performance, reliability, security, and maintainability
  • Lead by example through clean, well-tested code, thoughtful design reviews, and pragmatic technical decisions
  • Collaborate closely with Product Management, QA, and other engineers throughout the SDLC
  • Provide technical mentorship and guidance to other engineers on the team
  • Diagnoses and resolves complex production issues across distributed systems
  • Ensure solutions meet eClinical Solutions quality standards and applicable industry regulations
  • Contribute to technical documentation including design specs, acceptance criteria, and release notes

AI & Modern Engineering Focus

We're actively incorporating AI-powered capabilities into our platform, and you'll help shape how this is done responsibly and effectively in an enterprise environment. This includes:

  • Integrating LLMs and AI services into .NET- and Python-based systems
  • Designing and implementing AI-assisted workflows, copilots, or intelligent automation features
  • Working with agentic AI patterns (e.g., task orchestration, tool-using agents, workflow automation)
  • Applying prompt engineering, evaluation techniques, and guardrails to ensure reliability and compliance
  • Collaborating with data and platform teams to operationalize AI-not just prototype it

Deep ML expertise is not required-we're looking for strong engineers who understand how to apply AI capabilities in real products.

Take the first step toward your dream career.ย  Here is what we are looking for in this role.ย 

ย Qualifications:

  • Bachelor's or Master's degree in Computer Science or equivalent practical experienceย 
  • 10+ years in software design and development using the Microsoft technology stack preferredย 
  • Expert-level proficiency inย C#, .NET, and ASP.NET (MVC/Web APIs)
  • Strong experience buildingย full-stack web applications (Angular, TypeScript, HTML, CSS)
  • Solid understanding ofย software design principles, patterns, and best practices
  • Experience across the fullย Software Development Lifecycle (Agile preferred)
  • Proven ability to work independently while collaborating effectively in a fast-paced environment
  • Excellent communication, documentation, and technical leadership skills

AI & Platform Experience

  • Hands-on experience integrating LLM-based services (e.g., OpenAI, Azure OpenAI, or similar) into applications
  • Experience using Python and/or .NET alongside AI/LLM workflows
  • Familiarity with agent-based or workflow-driven AI architectures is a strong plus
  • Understanding of secure and responsible AI usage in enterprise systems

Nice to Have

  • Strong SQL expertise (Microsoft SQL Server preferred), including performance tuning
  • Experience with microservices, distributed systems, and cloud platforms (AWS preferred)
  • Secure development experience, including awareness of common vulnerabilities and mitigations
  • Experience with clinical trial data, life sciences, or regulated SaaS environments
  • Experience building data visualizations or analytics-driven user experiences

Accelerate your skills and career within a fast-growing company while impacting the future of healthcare. We have shared our story, now we look forward to learning yours!

eClinical is a winner of the 2025 Top Workplaces USA Award for Remote Work! We have also received numerous Top Workplaces Culture Excellence Awards celebrating our exceptional company vision, values, and work-life balance. See all the details here: https://topworkplaces.com/company/eclinical-solutions/

eClinical Solutions is a people first organization. Our inclusive culture values the contribution that diversity brings to our business. We celebrate individual experiences that connect us and that inspire innovation in our community. Our team seeks out opportunities to learn, grow and continuously improve. Bring your authentic self, you are welcome here!

We are proud to be an equal opportunity employer that values diversity. Our management team is committed to the principle that employment decisions are based on qualifications, merit, culture fit and business need.

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