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Remote Prompt Engineer Jobs in Indianapolis, IN (NOW HIRING)

Kobie Marketing

AI Engineer

Indianapolis, IN · Remote

As a remote-first organization headquartered in St. Petersburg, Florida, Kobie values meaningful in ... Implement guardrails around tool execution: auth scoping, input/output validation, PII and prompt ...

All JobsPrompt Engineer JobsRemote Prompt Engineer JobsRemote Prompt Engineer Jobs in Indianapolis, IN

Remote Prompt Engineer information

See Indianapolis, IN salary details

$12

$53

$77

How much do remote prompt engineer jobs pay per hour?

As of Aug 22, 2026, the average hourly pay for remote prompt engineer in Indianapolis, IN is $53.52, according to ZipRecruiter salary data. Most workers in this role earn between $38.37 and $71.25 per hour, depending on experience, location, and employer.

What is a remote prompt engineer?

A Remote Prompt Engineer designs, refines, and optimizes prompts to improve interactions between users and AI models. They work with natural language processing (NLP) systems to enhance response accuracy and relevance. This role often involves testing different prompts, analyzing AI outputs, and collaborating with developers or researchers to fine-tune language models. Since the position is remote, engineers use online tools and communication platforms to collaborate with teams and stay updated on AI advancements.

What are the key skills and qualifications needed to thrive as a remote prompt engineer?

To thrive as a Remote Prompt Engineer, you need expertise in natural language processing, prompt design, and a background in computer science or a related field. Familiarity with AI platforms (such as OpenAI or Anthropic APIs), programming languages like Python, and prompt engineering tools is highly valuable. Outstanding communication, collaboration, and problem-solving skills help remote team members excel in optimizing AI performance. These competencies ensure tailored, effective AI solutions and smooth, results-driven teamwork from a remote environment.

What does a typical workday look like for a remote prompt engineer?

As a Remote Prompt Engineer, your workday often involves designing and testing prompts for various AI models, collaborating with product managers and developers, and analyzing model outputs to refine interactions. You may also participate in virtual team meetings to discuss project goals, provide feedback on AI performance, and stay updated on new advancements in prompt engineering. Routine responsibilities include documenting prompt structures, troubleshooting model behavior, and integrating feedback from client or user testing. This dynamic and collaborative environment enables you to contribute creative solutions and drive continuous improvement in AI-driven applications.

Are remote prompt engineers still in demand?

Remote prompt engineers are currently in demand as organizations seek expertise in designing effective prompts for AI language models. The role often requires skills in natural language processing, AI tools, and programming, with many companies offering remote positions due to the digital nature of the work.

What is the salary of remote prompt engineer?

The salary of a remote prompt engineer typically ranges from $70,000 to $130,000 annually, depending on experience, skills, and the company's size. Entry-level positions may start lower, while experienced professionals with specialized knowledge in AI and machine learning can earn higher salaries. Compensation often includes benefits such as flexible schedules and opportunities for skill development.

What are the most commonly searched types of Prompt Engineer jobs in Indianapolis, IN?

The most popular types of Prompt Engineer jobs in Indianapolis, IN are:

What are popular job titles related to Remote Prompt Engineer jobs in Indianapolis, IN?

For Remote Prompt Engineer jobs in Indianapolis, IN, the most frequently searched job titles are:

What job categories do people searching Remote Prompt Engineer jobs in Indianapolis, IN look for?

The top searched job categories for Remote Prompt Engineer jobs in Indianapolis, IN are:

What cities near Indianapolis, IN are hiring for Remote Prompt Engineer jobs?

Cities near Indianapolis, IN with the most Remote Prompt Engineer job openings:

Remote Prompt Engineer jobs near you
Infographic showing various Remote Prompt Engineer job openings in Indianapolis, IN as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% Remote job distribution, with an average salary of $111,323 per year, or $53.5 per hour.

Senior AI Engineer Bioinformatics (Remote)

Marlabs

Indianapolis, IN • Remote

Full-time

Posted 25 days ago

Job description

Marlabs, a global AI and Digital Solutions Consulting firm, delivers intelligent solutions across AI, data, analytics, and product engineering. Since 2000, we have partnered with some of the largest healthcare, life sciences, financial services, and government organizations worldwide. As we continue to expand our global footprint, we have an exciting opportunity for a highly skilled Senior AI Engineer Bioinformatics to join our innovative and dynamic team.

Senior AI Engineer Bioinformatics | About You

As a Senior AI Engineer Bioinformatics, you are responsible for building modern, datadriven web applications that enable scientists and researchers to interact with complex datasets intuitively and efficiently. You enjoy working across the entire stack, from designing backend services and APIs to crafting responsive, elegant frontends. You thrive in environments where you collaborate closely with UX designers, scientists, and engineering partners to turn ideas into highimpact tools. You value clean architecture, reusable components, automated testing, and strong engineering best practices. You are energized by creating user experiences that simplify scientific workflows and make large-scale data accessible and actionable.

Senior AI Engineer Bioinformatics | Day-to-Day

  • Design, develop, and support scalable full-stack applications and AI-powered solutions using Python and modern development technologies.
  • Build and integrate Generative AI capabilities using LLM platforms such as OpenAI, Azure OpenAI, and Anthropic, including prompt engineering and context management.
  • Develop agentic workflows, tool integrations, and function-calling capabilities to automate complex business processes and enhance user experiences.
  • Integrate enterprise applications with platforms such as Microsoft 365, SharePoint, Microsoft Graph, ServiceNow, Jira, and Confluence through secure APIs.
  • Implement secure authentication, authorization, and secrets management practices while ensuring compliance with enterprise security standards.
  • Collaborate with cross-functional teams to deliver, deploy, and continuously improve applications through CI/CD pipelines, containerization, and modern DevOps practices.

Senior AI Engineer Bioinformatics | Skills & Experience

  • 7+ years of experience in full-stack application development within enterprise or technology-driven environments, with strong proficiency in Python.
  • Hands-on experience building AI and Generative AI solutions, including LLM API integrations, prompt engineering, token management, and conversational AI applications.
  • Strong experience with enterprise integrations, including Microsoft 365, Microsoft Graph, SharePoint, ServiceNow, Jira, Confluence, and REST APIs.
  • Expertise in secure application development, including SSO integrations (SAML, OAuth2, OIDC), API gateways, middleware, and secrets management best practices.
  • Experience with modern DevOps and cloud-native development, including containerization, CI/CD pipelines, deployment automation, and application lifecycle management.