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Remote Math Software Engineer Jobs in Houston, TX

Remote micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer's computational drug discovery project. In this role, you'll apply your expertise ...

Remote micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer's computational drug discovery project. In this role, you'll apply your expertise ...

Remote Job Overview We are seeking experienced GPU Programmers / Software Engineers to design and optimize GPU-based tasks for AI and LLM applications. You will apply your expertise in GPU ...

CUDA Engineering Expert Job Type: Contractor Location: Remote Job Overview We are seeking experienced CUDA Engineering Experts to support a cutting-edge GPU optimization project. You will apply your ...

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Build AI-integrated software: wire up LLM/AI APIs, design simple agent workflows, and ship AI ... Collaborate with senior engineers, ask great questions, and absorb engineering standards and best ...

Python: Sr. Software Engineer and Engineering Managers Locations: NYC, Texas - Each Position Can Be On Site, Partially or 100% Remote 115k - 185K base with some flex - Fulltime Depending On ...

Through an Employer of Record (EOR), we are looking for a new Director of Software Engineering in India to join our growing IT Team. This individual will report into our VP of IT and lead our ...

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Remote Math Software Engineer information

See Houston, TX salary details

$60.6K

$140.9K

$196.2K

How much do remote math software engineer jobs pay per year?

As of Aug 23, 2026, the average yearly pay for remote math software engineer in Houston, TX is $140,881.00, according to ZipRecruiter salary data. Most workers in this role earn between $114,600.00 and $165,200.00 per year, depending on experience, location, and employer.

What does a remote math software engineer do?

A Remote Math Software Engineer develops and maintains software applications that involve complex mathematical computations, algorithms, or data analysis. They often work on projects related to scientific computing, financial modeling, machine learning, or cryptography, collaborating with other engineers and mathematicians remotely. Their role includes writing efficient code, testing mathematical functions, and ensuring the accuracy and reliability of mathematical models within software products. Communication skills and self-motivation are essential, as most interactions occur online.

What are the key skills and qualifications needed to thrive as a remote math software engineer?

To thrive as a Remote Math Software Engineer, you need a strong background in mathematics, computer science, and programming, typically demonstrated through a relevant degree or equivalent experience. Familiarity with programming languages such as Python, C++, or Java, and experience with mathematical libraries, version control systems like Git, and possibly cloud computing platforms are essential. Excellent problem-solving abilities, communication skills, and self-motivation are crucial soft skills for remote collaboration and tackling complex mathematical challenges. These competencies are critical for developing robust math-based software solutions and contributing effectively to distributed teams.

How does a remote math software engineer typically collaborate with cross-functional teams to develop and implement mathematical algorithms?

Remote Math Software Engineers often work closely with product managers, data scientists, and other engineers through virtual meetings and collaborative platforms. They participate in regular stand-ups, code reviews, and brainstorming sessions to ensure that mathematical models and algorithms meet project requirements and are efficiently integrated into software products. Effective communication and documentation are key, as remote teams rely on clear specifications and feedback loops. Collaboration tools like Slack, Jira, and version control systems are commonly used to streamline teamwork and maintain project momentum.

What are the most commonly searched types of Math Software Engineer jobs in Houston, TX?

The most popular types of Math Software Engineer jobs in Houston, TX are:

What job categories do people searching Remote Math Software Engineer jobs in Houston, TX look for?

The top searched job categories for Remote Math Software Engineer jobs in Houston, TX are:

What cities near Houston, TX are hiring for Remote Math Software Engineer jobs?

Cities near Houston, TX with the most Remote Math Software Engineer job openings:

Bioinformatics Software Engineer

micro1 AI

Sugar Land, TX • Remote

$80 - $110/hr

Part-time

Posted 21 days ago


Job description

Role Title: Computational Biology & Cheminformatics Expert


Role Type: Contractor


Location: Remote


micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer’s computational drug discovery project. In this role, you'll apply your expertise to help train next-generation AI systems. Your work will shape how models learn, reason, and perform through high-quality, real-world input. No prior experience in AI is required — your domain knowledge is what matters.


Scope of Work

  1. Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods.
  2. Curate, annotate, and validate chemical and biological datasets (e.g., ChEMBL, PubChem, DrugBank) to support AI-driven discovery platforms.
  3. Evaluate compound-target interactions, ADMET properties, and lead optimization strategies by integrating chemical, biological, and clinical data sources.
  4. Provide expert insights on structure-activity and structure-property relationships (SAR/SPR), medicinal chemistry approaches, and experimental design considerations.
  5. Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios.
  6. Develop reproducible environments (e.g., using Docker) and automated testing pipelines to ensure task correctness and solvability.
  7. Assess and review AI-generated outputs for scientific rigor, accuracy, and practical relevance, delivering detailed written feedback and recommendations.


Preferred Qualifications

  1. Advanced expertise in Computational Biology, Cheminformatics, Medicinal Chemistry, Biochemistry, or related fields; advanced degree (PhD, MSc, PharmD) highly valued but not strictly required.
  2. Strong coding proficiency in Python (beyond analysis scripts), with hands-on experience building tools, pipelines, or testable code; familiarity with Git, GitHub, and Docker.
  3. Extensive experience with cheminformatics toolkits and platforms such as RDKit, KNIME, Schrödinger, OpenEye, or MOE.
  4. Proven track record in small-molecule drug discovery, SAR/QSAR evaluation, ADMET prediction, or virtual screening workflows.
  5. Comfort working with public chemical and bioactivity databases and integrating diverse datasets for scientific analysis.
  6. Demonstrated ability to clearly communicate complex chemical and biological concepts in written feedback and reports.
  7. Experience participating in multidisciplinary and/or remote projects; familiarity with AI-assisted coding tools is a plus.