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Remote Defense Contractor Software Engineer Jobs in Minnesota

Contractor Location: Remote micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer's computational drug discovery project. In this role, you'll ...

$140K - $160K/yr

US Remote Reports To: Engineering Manager What We're Looking For: * Strong background in Node.js ... Excellent debugging and problem-solving skills across software and hardware domains. * Ability to ...

Senior Systems Engineer

Saint Paul, MN ยท On-site +1

$130K - $165K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... remote access and automation), Secrets Manager (credential security), and CloudWatch (logging ... In-depth understanding of the aerospace and defense industry. * Knowledge of DoD software ...

Manager, Software Engineering

Minneapolis, MN ยท On-site +1

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Systems Engineer

Saint Paul, MN ยท On-site +1

$112K - $141K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... remote access and automation), Secrets Manager (credential security), and CloudWatch (logging ... In-depth understanding of the aerospace and defense industry. * Knowledge of DoD software ...

Showing results 41-60

Remote Defense Contractor Software Engineer information

What is a remote defense contractor software engineer?

A Remote Defense Contractor Software Engineer is a software developer who works for a company contracted by government defense agencies to build, maintain, or secure software systems, but does their work from a remote location instead of a traditional office or on-site facility. These engineers often develop applications for military or national security use, which can include communication systems, cybersecurity tools, or mission-critical platforms. Due to the sensitive nature of their work, they may require special security clearances and must adhere to strict security protocols even while working remotely.

What are the key skills and qualifications needed to thrive as a remote defense contractor software engineer?

To excel as a Remote Defense Contractor Software Engineer, you typically need a strong background in computer science or engineering, proficiency in programming languages like C++ or Java, and active security clearance. Familiarity with secure coding practices, embedded systems, and tools such as Git, Jira, and specialized defense software development environments is crucial. Excellent problem-solving, communication, and self-motivation are standout soft skills for remote collaboration and meeting strict project requirements. These competencies ensure secure, reliable software delivery and effective teamwork in sensitive, mission-critical defense projects.

How does a remote defense contractor software engineer typically collaborate with team members and stakeholders given security and communication constraints?

Remote Defense Contractor Software Engineers often work with multidisciplinary teams, including developers, project managers, and cybersecurity specialists. Collaboration is facilitated through secure, government-approved communication platforms and version control systems that comply with strict security protocols. Regular virtual meetings and documentation are essential to ensure alignment on project requirements and updates. While remote work offers flexibility, engineers must be diligent in following procedures for handling sensitive information and may sometimes need to access secure facilities for classified work. Effective communication and adaptability are key to overcoming the challenges of working in a highly regulated, remote environment.

What is the difference between Remote Defense Contractor Software Engineer vs Remote Cybersecurity Software Engineer?

AspectRemote Defense Contractor Software EngineerRemote Cybersecurity Software Engineer
Required CredentialsBachelor's in CS or related, security clearances often preferredBachelor's in CS, Cybersecurity, or related; certifications like CISSP beneficial
Work EnvironmentDefense contractors, government projects, secure facilitiesTech companies, security firms, government agencies
Employer & Industry UsagePrimarily defense and military sectorsPrimarily cybersecurity and IT sectors
Common Search & ComparisonOften compared for security clearance and defense projectsCompared for network security and threat mitigation roles

The Remote Defense Contractor Software Engineer typically works on defense and military projects requiring security clearances, while the Remote Cybersecurity Software Engineer focuses on protecting networks and systems from cyber threats. Both roles require strong technical skills, but their industries and project types differ significantly.

What are the most commonly searched types of Defense Contractor Software Engineer jobs in Minnesota?

The most popular types of Defense Contractor Software Engineer jobs in Minnesota are:

What are popular job titles related to Remote Defense Contractor Software Engineer jobs in Minnesota?

For Remote Defense Contractor Software Engineer jobs in Minnesota, the most frequently searched job titles are:

What job categories do people searching Remote Defense Contractor Software Engineer jobs in Minnesota look for?

The top searched job categories for Remote Defense Contractor Software Engineer jobs in Minnesota are:

What cities in Minnesota are hiring for Remote Defense Contractor Software Engineer jobs?

Cities in Minnesota with the most Remote Defense Contractor Software Engineer job openings:

Bioinformatics Software Engineer

micro1 AI

Rochester, MN โ€ข Remote

$80 - $110/hr

Part-time

Posted 16 days ago


Job description

Role Title: Computational Biology & Cheminformatics Expert


Role Type: Contractor


Location: Remote


micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customerโ€™s computational drug discovery project. In this role, you'll apply your expertise to help train next-generation AI systems. Your work will shape how models learn, reason, and perform through high-quality, real-world input. No prior experience in AI is required โ€” your domain knowledge is what matters.


Scope of Work

  1. Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods.
  2. Curate, annotate, and validate chemical and biological datasets (e.g., ChEMBL, PubChem, DrugBank) to support AI-driven discovery platforms.
  3. Evaluate compound-target interactions, ADMET properties, and lead optimization strategies by integrating chemical, biological, and clinical data sources.
  4. Provide expert insights on structure-activity and structure-property relationships (SAR/SPR), medicinal chemistry approaches, and experimental design considerations.
  5. Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios.
  6. Develop reproducible environments (e.g., using Docker) and automated testing pipelines to ensure task correctness and solvability.
  7. Assess and review AI-generated outputs for scientific rigor, accuracy, and practical relevance, delivering detailed written feedback and recommendations.


Preferred Qualifications

  1. Advanced expertise in Computational Biology, Cheminformatics, Medicinal Chemistry, Biochemistry, or related fields; advanced degree (PhD, MSc, PharmD) highly valued but not strictly required.
  2. Strong coding proficiency in Python (beyond analysis scripts), with hands-on experience building tools, pipelines, or testable code; familiarity with Git, GitHub, and Docker.
  3. Extensive experience with cheminformatics toolkits and platforms such as RDKit, KNIME, Schrรถdinger, OpenEye, or MOE.
  4. Proven track record in small-molecule drug discovery, SAR/QSAR evaluation, ADMET prediction, or virtual screening workflows.
  5. Comfort working with public chemical and bioactivity databases and integrating diverse datasets for scientific analysis.
  6. Demonstrated ability to clearly communicate complex chemical and biological concepts in written feedback and reports.
  7. Experience participating in multidisciplinary and/or remote projects; familiarity with AI-assisted coding tools is a plus.