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Real World Evidence Rwe information

What is real world evidence (RWE)?

Real World Evidence (RWE) refers to clinical evidence regarding the usage and potential benefits or risks of a medical product, derived from analysis of real-world data (RWD). This data is collected from sources outside of traditional clinical trials, such as electronic health records, insurance claims, patient registries, and wearable devices. RWE plays a crucial role in understanding how treatments work in routine clinical practice, informing regulatory decisions, and supporting drug development and market access. Organizations use RWE to complement clinical trial data, improving healthcare outcomes and patient care.

How does a real world evidence (RWE) professional collaborate with cross-functional teams?

RWE professionals often work closely with colleagues from epidemiology, health economics, medical affairs, and regulatory affairs to design and execute studies using real-world data. Collaboration is essential, as RWE findings support evidence generation for regulatory submissions, market access, and post-marketing surveillance. Regular meetings, data-sharing sessions, and joint project planning are common, ensuring all stakeholders are aligned on study objectives, methodologies, and data interpretation. This collaborative environment helps translate complex data into actionable insights that support decision-making across the organization.

What are the key skills and qualifications needed to thrive as a real world evidence (RWE) professional?

To thrive as a Real World Evidence (RWE) professional, you need a strong background in epidemiology, biostatistics, and data analysis, often supported by an advanced degree in a relevant scientific field. Familiarity with statistical software (such as SAS, R, or Python), real-world data sources (like EHRs and claims databases), and regulatory guidelines (FDA/EMA) is essential. Strong communication, problem-solving, and cross-functional collaboration skills help convey complex findings to stakeholders and integrate RWE into decision-making. These competencies are crucial for generating credible insights that inform clinical, regulatory, and commercial strategies in the healthcare industry.

What is the difference between Real World Evidence Rwe vs Clinical Data Analyst?

AspectReal World Evidence RweClinical Data Analyst
Required credentialsTypically requires a background in healthcare, epidemiology, or biostatistics, often with a master's or PhDUsually requires a degree in health informatics, biostatistics, or related fields, with similar certifications
Work environmentPrimarily in healthcare, pharmaceutical, or research organizations analyzing real-world dataIn clinical research settings, hospitals, or pharmaceutical companies analyzing clinical trial data
Employer and industry usageUsed by pharma companies, healthcare providers, and research institutions to generate real-world insightsUsed by research organizations, hospitals, and pharma for clinical trial data management and analysis

Real World Evidence Rwe professionals focus on analyzing data from real-world settings like electronic health records and insurance claims, while Clinical Data Analysts primarily work with clinical trial data. Both roles require strong analytical skills and related credentials, but Rwe specialists emphasize real-world data sources to inform healthcare decisions.

What job categories do people searching Real World Evidence Rwe jobs in Leesburg, VA look for?

The top searched job categories for Real World Evidence Rwe jobs in Leesburg, VA are:

What cities near Leesburg, VA are hiring for Real World Evidence Rwe jobs?

Cities near Leesburg, VA with the most Real World Evidence Rwe job openings:

Real World Evidence Rwe jobs near you
Infographic showing various Real World Evidence Rwe job openings in Leesburg, VA as of August 2026, with employment types broken down into 82% Full Time, and 18% Contract. Highlights an 74% In-person, 4% Hybrid, and 22% Remote job distribution.

Senior Director, Global Oncology RWD Platform

AstraZeneca GmbH

Gaithersburg, MD • On-site

$229 - $344/hr

Other

Medical, Dental, Vision, Retirement, PTO

Posted 23 days ago

Job description

Join the NextGen Sciences team, within AstraZeneca Global Medical Affairs’ Oncology Evidence Generation to Publications (EG2P) organization as a Senior Director, AstraZeneca Global Oncology RWD Platform, including the AZ Partnerships in Oncology Maximising real world evidence (APOLLO) platform.

APOLLO is a key EG2P initiative to foster innovation in global real world data generation linked to AZ medical strategies and priorities. We're looking for a multidimensional individual who can drive the creation and maintenance of this multi-asset platform, including identification of potential new partners for data access, collection or analysis, development of standard operating procedures, and development of a roadmap to ensure APOLLO will support multiple use cases at launch, including insights gathering, internal decision making and evidence generation. This role is a phenomenal opportunity to contribute to AZ oncology portfolio by providing access to new sources of real world treatment patterns and outcomes in key tumor types across the globe.

The Senior Director, Global Oncology RWD Platform is responsible for the development and maintenance of a new platform for global oncology real world data, and implementation of innovative approaches to support the generation of timely and impactful real world evidence across the AstraZeneca oncology portfolio.

Typical Accountabilities
  • This person will be responsible for multiple initiatives within NGS and EG2P, and therefore must be comfortable with ambiguity and able to flex across different workstreams, cross-functional teams and discussion topics.
  • Identify and assess potential new partners for potential inclusion in APOLLO and conduct feasibility assessments to ensure fit for purpose with APOLLO strategy of expanding access to real world oncology data
  • Develop and implement a Roadmap to prepare the organization for APOLLO RWD ingestion and utilization
  • Develop a communication plan for internal AZ partners, including Evidence Generation to Publications (EG2P), broader Global Medical Affairs organization, regional and local teams regarding APOLLO status
  • In collaboration with other EG2P or OBU teams, develop dashboards summarizing key metrics from APOLLO RWD sources for internal AZ partners
  • Create and implement strategies that drive the implementation of APOLLO, ensuring availability of timely and meaningful data to support AZ’s global oncology real world evidence needs.
  • Foster collaborative relationships with external experts to help shape future APOLLO initiatives
  • Provide leadership and mentoring to teams and individuals to upskill and develop future capabilities in line with AstraZeneca’s dedication to a culture of performance development and lifelong learning.
  • Ensure that all Medical and business activities are carried out in compliance with AZ standards, standard operating procedures, and external regulations.
Essential Qualifications
  • Minimum 10 years experience in the pharmaceutical industry with advanced degree in epidemiology, outcomes research, statistics and/or related subject areas.
  • Demonstrated experience building real world data (RWD) assets and real world evidence (RWE) generation.
  • Deep understanding of the utilization of RWD for multiple use cases, and ability to guide decisions regarding data structure, inclusion criteria, etc, to support those use cases.
  • In-depth expertise with research methods for real world research, HEOR projects including pharmacoepidemiologic models.
  • Proven track record of using tools for data curation / abstraction of unstructured information from electronic health records
  • Strong verbal and written communication skills, particularly around research methods and use of RWD in global and local settings
Desirable Qualifications
  • PhD in relevant area (Health Economics, Public Health, etc)
  • Expert reputation within the business and industry related to RWE
  • Scientific and business expertise in oncology with a strong understanding of key global and regional issues and concerns.
  • Recognized as a subject matter authority with deep technical expertise in global RWE generation
  • Extensive knowledge of the latest technical and regulatory expectations related to generation / use of RWD.
  • Familiarity with the latest research and thinking in data visualization.
  • Experience in building dashboards or other tools for summarizing data.
  • Effective problem and conflict resolution skills and validated team focus.
Compensation & Benefits
  • The annual base pay (or hourly rate of compensation) for this position ranges from $229,047 to $343,570.
  • Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
  • Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles.

Date Posted 07-Aug-2026

Closing Date 20-Aug-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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