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Qsp Modeling Job Jobs (NOW HIRING)

Trihydro Corporation

Staff Scientist - QSP

Arcata, CA · On-site

$70K - $80K/yr

Job Title Staff Scientist - QSP Job Type Full-time Location Arcata, CA 95518 US Roseville, CA 95747 ... Supports team development through collaboration, knowledge sharing, and modeling professional ...

Allucent

Director, Clinical Pharmacology

Cary, NC · Remote

... and QSP modeling. * Oversee the development of statistical and PK analysis plans, standalone PK/PD reports, and PK/PD sections of clinical study reports, and take the lead in reviewing clinical ...

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How much do qsp modeling job jobs pay per hour?

As of Jun 6, 2026, the average hourly pay for qsp modeling job in the United States is $40.33, according to ZipRecruiter salary data. Most workers in this role earn between $31.25 and $43.51 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a QSP (Quantitative Systems Pharmacology) Modeler, and why are they important?

To thrive as a QSP Modeler, a strong background in pharmacology, mathematics, and computational modeling—typically supported by an advanced degree in a related field—is essential. Familiarity with modeling software such as MATLAB, R, or SimBiology, and experience with data analysis tools are commonly required, along with knowledge of regulatory standards. Strong problem-solving, communication, and interdisciplinary collaboration skills set outstanding QSP modelers apart. These competencies are crucial for developing robust models that inform drug development decisions and facilitate effective communication across scientific and clinical teams.

How does a QSP Modeling professional typically collaborate with cross-functional teams in pharmaceutical development?

In a QSP (Quantitative Systems Pharmacology) Modeling role, professionals frequently work alongside pharmacologists, clinicians, statisticians, and regulatory experts to translate complex biological data into actionable insights. Collaboration is key, as QSP modelers help design experiments, interpret results, and inform decision-making on drug dosing, efficacy, and safety. Effective communication skills are essential, since modelers must present technical findings in a way that's accessible to non-modeling stakeholders. This cross-functional teamwork is vital for advancing drug candidates through various stages of development.

What are QSP modeling jobs?

QSP modeling jobs involve working as a Quantitative Systems Pharmacology (QSP) modeler, where professionals build and analyze mathematical and computational models to understand drug actions and biological systems. These roles are common in pharmaceutical and biotechnology companies, and require knowledge of pharmacology, biology, mathematics, and computer science. QSP modelers collaborate with cross-functional teams to inform drug discovery, development strategies, and decision-making processes. The goal is to predict the effects of drugs, optimize dosing, and reduce the risk of late-stage clinical failures.

What is the difference between Qsp Modeling Job vs Qsp Analyst?

AspectQsp Modeling JobQsp Analyst
Required CredentialsDegree in engineering, finance, or related field; proficiency in Qsp softwareSimilar credentials; often includes certifications in modeling or analysis
Work EnvironmentEngineering teams, project sites, or corporate officesFinancial or technical departments, consulting firms
Employer & Industry UsageEnergy, manufacturing, or engineering firmsFinancial services, consulting, or energy sectors
Common Search & ComparisonYesYes

The Qsp Modeling Job focuses on creating and analyzing models using Qsp software within engineering or technical contexts. The Qsp Analyst typically performs similar modeling tasks but may emphasize data analysis and reporting. Both roles require technical skills and industry knowledge, but the Qsp Modeling Job often involves more hands-on model development, while the Qsp Analyst may focus on interpreting results for decision-making.

Infographic showing various Qsp Modeling Job job openings in the United States as of May 2026, with employment types broken down into 58% Temporary, 5% Contract, and 37% Nights. Highlights an 81% Physical, 2% Hybrid, and 17% Remote job distribution, with an average salary of $83,896 per year, or $40.3 per hour.
Quantitative Systems Pharmacology (QSP) Lead - Rare Disease Portfolio

Quantitative Systems Pharmacology (QSP) Lead - Rare Disease Portfolio

Shionogi Inc.

Florham Park, NJ • On-site

$24.50 - $33.25/hr

Other

Posted 11 days ago

Job description

Overview
The Quantitative Systems Pharmacology (QSP) Lead is responsible for establishing and operationalizing QSP to support development decisions in rare disease programs. This role serves as the scientific and strategic owner of QSP across high-priority programs, with responsibility for both building an end-to-end QSP operating model and delivering modeling outputs that inform clinical and development strategy.
The incumbent will design and implement the full QSP workflow-from intake and prioritization through model development, technical review, and integration into development decisions-while ensuring outputs are reproducible, reviewable, and aligned with program needs. The role requires a balance of hands-on modeling and scientific oversight, including the effective use and management of external modeling partners, while retaining full ownership of modeling strategy and outputs.
This position operates in a highly matrixed environment and partners closely with cross-functional stakeholders to translate quantitative insights into actionable development decisions. The role is focused on high-impact rare disease programs, particularly those requiring integration across biomarkers, disease progression, and regulatory considerations, and is expected to define a roadmap for scaling QSP capabilities over time.
Responsibilities
Duties and Responsibilities:
  • Design and implement an end-to-end QSP operating model, including standardized deliverables, timelines, quality gates, documentation, and decision packages that ensure modeling outputs are reproducible, reviewable, and actionable in governance forums.
  • Identify and prioritize high-impact QSP use cases aligned with key program decision points, translating modeling needs into focused work plans that maximize development impact.
  • Develop and apply mechanistic or semi-mechanistic disease and drug models (e.g., ODE-based frameworks), ensuring strong documentation, version control, and reproducibility.
  • Develop and apply mechanistic and semi-mechanistic QSP models, including virtual patient simulations and in silico trials, to inform dose selection, trial design, and risk assessment, ensuring strong documentation, reproducibility, and scientific rigor.
  • Generate QSP models, virtual patients, and in-silico trial simulations where appropriate and high-value, particularly in early capability build-out or critical decision moments. Balance hands-on modeling with strategic oversight, determining when to execute internally versus leverage external partners based on impact, timing, and complexity.
  • Identify, evaluate, and manage external QSP or disease-modeling vendors, including scope definition, deliverables, timelines, and quality oversight.
  • Retain full scientific and technical ownership of all externally generated outputs, ensuring alignment with internal assumptions, standards, and decision needs.
  • Use virtual patient approaches and in-silico trials to derisk development, explore dose and regimen options, and assess disease heterogeneity and scenario sensitivity.
  • Produce clear, decision-grade analysis packages explaining assumptions, limitations, sensitivity analyses, and implications for development and trial design.
  • Develop and deliver clear, decision-focused modeling outputs, including assumptions, limitations, and sensitivity analyses, and translate complex quantitative insights into actionable recommendations for cross-functional teams, senior leadership, and governance bodies.
  • Drive alignment on priorities, expectations, and delivery timelines in a matrix environment.
  • Partner closely with Clinical Development, Clinical Pharmacology/PMx, Biostatistics, Translational, Regulatory, and other functions to align on QSP priorities, expectations, and delivery timelines in a matrix environment.
  • Define a phased roadmap for scaling QSP capabilities over time, including recommendations for future hiring and optimal use of external partners.
  • Other duties as assigned.

Qualifications:
  • PhD in Biomedical Engineering, Systems Biology/Pharmacology, Applied Mathematics, Computational Biology, or a related quantitative discipline preferred.
  • 12+ years of experience in pharmaceutical/biotechnology development with a minimum of 3 years of QSP modeling
  • Demonstrated experience delivering QSP or mechanistic modeling to inform drug development decisions, including dose selection, trial design, and/or regulatory strategy.
  • Proven ability to operate in a matrix environment, integrating quantitative insights into cross-functional decision-making.
  • Strong expertise in QSP modeling frameworks (e.g., MATLAB, R, Julia, or Open Systems Pharmacology Suite), with strong emphasis on model development, validation, and reproducibility.
  • Rare disease experience preferred.

Other Requirements:
  • This position has significant managerial and decision-making authority.
  • Ability and willingness to travel approximately 25-35% of the year both domestically and internationally
  • Must live a commutable distance to our US Corporate Headquarters in Florham Park, NJ. Office presence required at least 50% of the time per month.

Additional Information:
The base salary range for this full-time position is $260,000 - $295,000. Individual pay is determined by several factors, which include but are not limited to: job-related skills, experience, and relevant education or training. The range does not include the comprehensive benefits, bonus, long-term incentive, applicable allowances, or any additional compensation that may be associated with this role.
EEO
Shionogi Inc. is an equal opportunity employer supporting individuals with disabilities and veterans. All qualified applicants will receive equal consideration for employment opportunities based on valid job requirements without regard to race, color, religion, sex (including pregnancy), marital status, national origin, age, ancestry, citizenship, disability, genetic information, status as a disabled veteran, a recently separated veteran, Active Duty Wartime or Campaign Badge Veterans, and Armed Forces Service Medal Veterans, or any other characteristic protected by applicable law. It is the policy of Shionogi Inc. to undertake affirmative action for protected veterans and individuals with disabilities in compliance with all federal, state, and local requirements to recruit a diverse pool of protected veteran and individuals with disabilities applicants and to ensure that our employment practices are, in fact, non-discriminatory.
If you are qualified individual with a disability or a disabled veteran, you may request a reasonable accommodation if you are unable or limited in your ability to use or access this website to apply for a vacancy as a result of your disability. You can request accommodations by calling 973-307-3550 or by sending an email to ShionogiHR@shionogi.com.
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About Shionogi

Sourced by ZipRecruiter

Industry

Pharmaceutical and medicine manufacturing

Company size

201 - 500 Employees

Headquarters location

Florham Park, NJ, US

Year founded

2001

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