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Pyxis Jobs in Missouri (NOW HIRING)

American Traveler

Travel ICU RN

Saint Louis, MO · On-site

Uses Pyxis and SBAR handoff processes * No chemotherapy, central line insertion, or chest tube insertion performed by nursing staff * Nurses draw their own phlebotomy Requirements * Active MO or ...

BJC

Clinical Pharmacist Lead

Saint Louis, MO · On-site

$115K - $137K/yr

Manage inventory, medication prep, and Pyxis refills * Support medication delivery, patient counseling, and prior authorizations * Participate in REMS programs and departmental committees

BJC HealthCare

Clinical Pharmacist Lead

Saint Louis, MO · On-site

$107K - $128K/yr

Manage inventory, medication prep, and Pyxis refills * Support medication delivery, patient counseling, and prior authorizations * Participate in REMS programs and departmental committees

BJC HealthCare

Pharmacy Student

Saint Louis, MO · On-site

$15.75 - $19.25/hr

This is a student pharmacist working in both sterile and non-sterile spaces preparing medications, delivering medications, and refilling Pyxis machines. Grow you career with our experience team at St.

BJC HealthCare

Inpatient Pharmacy Tech 1

Saint Louis, MO · On-site

$15.75 - $19.25/hr

In this role, you will work in both sterile and non-sterile spaces preparing medications, delivering medications, and refilling Pyxis machines. Grow you career with our experience team at St. Louis ...

BJC HealthCare

Clinical Pharmacist Lead

Saint Louis, MO · On-site

$113K - $157K/yr

Manage inventory, medication prep, and Pyxis refills * Support medication delivery, patient counseling, and prior authorizations * Participate in REMS programs and departmental committees

Prime Staffing

Travel ICU RN

Saint Louis, MO · On-site

No chemotherapy, central lines, chest tubes, nurses draw own phlebotomy-Pyxis/EPIC/SBAR handoff-Provider Support: Interpretation Services, IV Teams, Pharmacy, PT, Social Services, Radiology ...

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Pyxis information

See Missouri salary details

$13

$18

$24

How much do pyxis jobs pay per hour?

As of Aug 11, 2026, the average hourly pay for pyxis in Missouri is $18.07, according to ZipRecruiter salary data. Most workers in this role earn between $15.77 and $19.18 per hour, depending on experience, location, and employer.

What is the difference between Pyxis vs Pharmacist?

AspectPyxisPharmacist
CredentialsTypically requires pharmacy technician certificationRequires Doctor of Pharmacy (Pharm.D.) degree and licensure
Work EnvironmentHospital or healthcare facility medication dispensing systemsPharmacies, hospitals, clinics, and healthcare settings
Employer & IndustryHospitals, healthcare providers, pharmacy automation companiesPharmacies, hospitals, healthcare organizations
Primary RoleOperating medication dispensing systems, inventory managementPatient medication counseling, prescribing, and medication management

Pyxis is a medication management system used in healthcare settings, primarily operated by pharmacy technicians or staff. Pharmacists, on the other hand, are licensed healthcare professionals responsible for patient medication therapy. While Pyxis automates medication dispensing, pharmacists oversee medication safety and patient care. Both roles are essential in healthcare but serve different functions within the medication management process.

What are the key skills and qualifications needed to thrive as a Pyxis system administrator?

To thrive as a Pyxis System Administrator, you need a solid understanding of pharmacy operations, IT troubleshooting, and healthcare compliance, typically supported by experience in healthcare technology or pharmacy environments. Proficiency with Pyxis MedStation systems, database management, and relevant certifications like CompTIA or pharmacy technician credentials are often required. Strong problem-solving skills, attention to detail, and effective communication set top candidates apart. These abilities ensure the secure and efficient management of medication dispensing, supporting patient safety and regulatory compliance.

What is a Pyxis?

A Pyxis is typically a reference to the Pyxis MedStation, an automated medication dispensing system commonly used in hospitals and healthcare facilities. The job related to Pyxis usually involves managing, stocking, and troubleshooting the Pyxis MedStation to ensure medications are securely stored and accurately dispensed to authorized healthcare professionals. Staff responsible for Pyxis may include pharmacy technicians, nurses, or specialized Pyxis administrators, and their duties often include inventory management, system maintenance, and ensuring compliance with medication safety protocols.

What does a Pyxis system administrator do?

A Pyxis system administrator is responsible for managing and maintaining automated medication dispensing systems in healthcare facilities. Their daily tasks often include ensuring system accuracy, troubleshooting technical issues, maintaining user access, training staff on system use, and coordinating with pharmacy and IT departments. Administrators also monitor inventory levels, perform regular audits, and implement software updates to ensure compliance with healthcare regulations. Collaboration with nurses, pharmacists, and IT professionals is essential for smooth operations and timely medication delivery.

What are jobs that work with a Pyxis machine?

Pyxis MedStation is an automated system used by hospitals and other healthcare facilities to dispense medication and monitor inventory levels. Jobs that involve Pyxis equipment include Pyxis administrator, pharmacy automation consultant, O.R. materials coordinator, and pharmacy technician. As a Pyxis administrator, you are the team leader for the automated medication distribution system, and your responsibilities and duties revolve around maintaining the controlled substance inventory and monitoring usage. Materials coordinators use Pyxis to carry out warehousing and supply functions for their facilities, while technicians handle medication dosing and distribution under the supervision of a registered pharmacist. As a pharmacy automation consultant, you help facilities adopt and implement a Pyxis system.

More about Pyxis jobs
What are the most commonly searched types of Pyxis jobs in Missouri? The most popular types of Pyxis jobs in Missouri are:
What are popular job titles related to Pyxis jobs in Missouri? For Pyxis jobs in Missouri, the most frequently searched job titles are:
What job categories do people searching Pyxis jobs in Missouri look for? The top searched job categories for Pyxis jobs in Missouri are:
What cities in Missouri are hiring for Pyxis jobs? Cities in Missouri with the most Pyxis job openings:
Pyxis jobs near you
Infographic showing various Pyxis job openings in Missouri as of August 2026, with employment types broken down into 86% Full Time, and 14% Part Time. Highlights an 100% In-person job distribution, with an average salary of $37,589 per year, or $18.1 per hour.

Travel ICU RN

American Traveler

Saint Louis, MO • On-site

Contractor

Medical, Dental, Vision, Life, Retirement

Posted 20 days ago

Job description

American Traveler is seeking a travel nurse RN ICU - Intensive Care Unit for a travel nursing job in St. Louis, Missouri.

Job Description & Requirements
  • Specialty: ICU - Intensive Care Unit
  • Discipline: RN
  • Start Date: 09/14/2026
  • Duration: 13 weeks
  • 48 hours per week
  • Shift: 12 hours, nights
  • Employment Type: Travel
Assignment Overview
  • Shift: Nights, 4x12hrs
  • Hours: 48 hrs/wk
  • Start Date: Sep 14, 2026
  • Length: 13 weeks
  • Openings: 1
Description

American Traveler is hiring an experienced RN for an ICU/Oncology position requiring 2 years of ICU experience and a MO or compact RN license.

Details
  • Work in the ICU/Oncology unit of a Magnet-designated, Level I Trauma teaching hospital
  • Average daily census of 21 with 25 beds
  • Patient ratio of 1:2
  • Night shift, 4x12 hours, 19:00-7:30
  • Can sign for 36 or 48 hours per week
  • Every other weekend required
  • No on-call responsibilities
  • Floating required within oncology service line/ICUs, with potential to float anywhere
  • Uses Epic for charting
  • Uses Pyxis and SBAR handoff processes
  • No chemotherapy, central line insertion, or chest tube insertion performed by nursing staff
  • Nurses draw their own phlebotomy
Requirements
  • Active MO or compact RN license required (no issuance if tied to another compact state)
  • Current certifications: BLS and ACLS
  • BSN preferred
  • Minimum 2 years of ICU experience required
  • Must pass Relias EKG exam covering interpretation and management of dysrhythmias
  • Epic charting experience required
  • Teaching hospital experience preferred
  • Skills required: interpretation and management of dysrhythmias, multi-system organ failure care, IV insulin protocols, arterial line management, blood product administration, central line care/management, PICC line management, starting IVs, continuous IV sedation, procedural sedation administration, titration of cardiac and vasoactive drips, BiPAP, ventilator management, high flow nasal cannula, ABG interpretation, suctioning (ETT, NT), infection prevention, isolation precautions/PPE, phlebotomy, and surgical wound/wound vac care
  • Chest tube insertion/removal assistance preferred
  • Pending MO or IL license accepted at time of submission
Additional Information
  • Provide ICU-level nursing care to an oncology patient population with support from Interpretation Services, IV Teams, Pharmacy, PT, Social Services, Radiology, Respiratory, Rapid Response Teams, Patient Transport, and Unit Secretary
  • First-time travelers are welcome to apply
  • No more than 7 days of RTO permitted per 13-week contract, with no RTO allowed during the first week of the assignment
  • Must reside outside a 75-mile radius to be eligible for this position
  • Standard travelers may work up to an 18-month period, followed by a required 3-month break in service
  • Permanent employees of BJC or Saint Luke's must wait 1 year before returning to any BJC facility as a traveler
  • Navy blue scrubs required
  • Facial hair must allow for proper respirator fit testing or must be shaved with no exceptions

American Traveler Job ID #P-739470. Pay package is based on 12 hour shifts and 48 hours per week (subject to confirmation) with tax-free stipend amount to be determined. Posted job title: Travel RN - ICU

About American Traveler

With over 25 years of experience, American Traveler has established a reputation for outstanding customer service. Our team ensures a smooth, worry-free experience for those starting on or expanding their travel nursing and allied careers.

With thousands of travel nursing and allied jobs nationwide, our attentive and approachable recruiters find positions that align perfectly with your career aspirations and personal requirements.

American Traveler offers exceptional benefits, including premium medical, dental, vision and life insurance beginning day one of your assignment, generous 401(k) match, substantial housing stipends, and more. Additionally, with 24/7 support and access to our in-house clinicians, you are assured confidence and comfort throughout your assignment.

With our team behind you, you can relax and enjoy a rewarding travel career.

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