ZipRecruiter

Log In

1

Python Llm Jobs in Saint Louis, MO (NOW HIRING)

MasterCard

Senior AI Engineer

O Fallon, MO · Hybrid

$97K - $134K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Develop high-performance Python backend services for LLM inference orchestration, async job handling, streaming responses, and distributed data workflows supporting high-throughput Gen AI operations.

Mastercard, Inc.

Senior AI Engineer

O Fallon, MO · On-site

$97K - $134K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... Python backend services for LLM inference orchestration, async job handling, streaming responses, and distributed data workflows supporting high-throughput Gen AI operations. • Engineer state ...

InterSources Inc

QA Test Engineer

Chesterfield, MO · On-site

$40.75 - $55.75/hr

Responsibilities : • 3+ years in QA automation or SDET-type work (adjust by level); 1+ year exposure to AI/LLM or ML-driven features is a plus. • Strong test automation in Python and/or Java ...

MasterCard

Manager, AI Engineering (Tester )

O Fallon, MO

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... Python programming skills with the ability to independently build test automation scripts, evaluation pipelines, and API-level integration tests; SQL proficiency required. Working knowledge of LLM ...

Kobie Marketing

AI Engineer

Saint Louis, MO · Remote

... clients an LLM-native way to work with complex loyalty logic. We're looking for a hands-on AI ... Build agent harnesses in Python using LangChain and LangGraph, including tool-calling, structured ...

Kobie Marketing

AI Engineer

Saint Louis, MO · Remote

... clients an LLM-native way to work with complex loyalty logic. We're looking for a hands-on AI ... Build agent harnesses in Python using LangChain and LangGraph, including tool-calling, structured ...

Merck Group

Staff Software Engineer

Saint Louis, MO · On-site

$110K - $165K/yr

  • Medical

  • Retirement

  • PTO

Preferred Qualifications: * 10+ years of software engineering experience, with deep recent time leading production AI/LLM systems * Proven expertise in Python and ML frameworks (MLFlow, TensorFlow ...

Stellar IT Group

BioTech Data Engineer

Saint Louis, MO · On-site

$111K - $133K/yr

Design and maintain API integrations with internal and external systems, including Python- and PySpark-based services and AI/LLM-powered APIs for advanced analytics and automation * Administer and ...

eTeam

Kafka Expert with Agentic AI Skills

Saint Louis, MO · On-site

$54.25 - $71.75/hr

... Python or Java. • Hands-on experience with Agentic AI and LLM frameworks such as LangChain, AutoGen, CrewAI, or Semantic Kernel. • Experience building autonomous AI workflows and AI-driven ...

Bespoke Labs

Machine Learning Engineer

Saint Louis, MO · On-site

... Python and deep learning proficiency (PyTorch preferred; familiar with training loops, optimizers, mixed precision) Hands-on experience with LLM post-training -- SFT, RLHF, PPO, DPO, or reward model ...

next page

Showing results 1-20

All JobsPython Llm JobsPython Llm Jobs in Saint Louis, MO

Python Llm information

See Saint Louis, MO salary details

$12

$56

$83

How much do python llm jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for python llm in Saint Louis, MO is $56.99, according to ZipRecruiter salary data. Most workers in this role earn between $46.97 and $64.76 per hour, depending on experience, location, and employer.

What is a Python LLM?

A Python LLM job involves working with Large Language Models (LLMs) using Python to develop, fine-tune, and deploy AI models. Responsibilities may include data preprocessing, prompt engineering, model optimization, and integration with applications. Professionals in this role often work with frameworks like TensorFlow, PyTorch, or Hugging Face Transformers. They may also contribute to improving model efficiency, reducing bias, and ensuring ethical AI usage.

What are the key skills and qualifications needed to thrive in the Python LLM position, and why are they important?

To excel as a Python LLM (Large Language Model) Engineer, you need strong skills in Python programming, machine learning, and natural language processing, typically supported by a degree in computer science or a related field. Proficiency with libraries such as TensorFlow, PyTorch, Hugging Face Transformers, and experience with model deployment platforms are often essential, alongside certifications in AI or data science. Effective communication, problem-solving abilities, and collaboration are important soft skills for working in interdisciplinary teams and delivering results in dynamic environments. These skills ensure the development, fine-tuning, and deployment of advanced language models that meet both technical and business objectives.

What are some common challenges faced by Python LLM engineers in their daily work?

Python LLM Engineers often encounter challenges related to optimizing model performance, managing large datasets, and adapting models to specific business needs. Working with large-scale language models requires balancing computational resource limitations with the need for high accuracy and efficiency. Collaboration with data scientists, product managers, and DevOps engineers is routine to ensure seamless model integration and deployment. Staying updated on the latest advancements in NLP and continuously improving models based on user feedback are also important aspects of the role.

What are popular job titles related to Python Llm jobs in Saint Louis, MO?

For Python Llm jobs in Saint Louis, MO, the most frequently searched job titles are:

What job categories do people searching Python Llm jobs in Saint Louis, MO look for?

The top searched job categories for Python Llm jobs in Saint Louis, MO are:

What cities near Saint Louis, MO are hiring for Python Llm jobs?

Cities near Saint Louis, MO with the most Python Llm job openings:

Python Llm jobs near you

Sr AI/ML Engineer local to St. Louis, MO

FEDRUS GLOBAL LLC

Saint Louis, MO • On-site

$99K - $136K/yr

Other

This job post has expired 1 day ago. Applications are no longer accepted.

Job description

We are looking for a skilled AI/ML Developer to join our agentic platform team. You will design, develop, and deploy LLM-powered agents and pipelines that directly serve field technicians in production. You will work closely with the platform architect and contribute to the core multi-agent orchestration system.

Required Skills & Experience

Must-Have

- 10+ years of software development with strong Python expertise in production environments

- 2+ years hands-on LLM development (LangChain, LangGraph, or equivalent frameworks)

- RAG pipeline experience - embeddings, vector search, re-ranking, answer generation

- LLM APIs - OpenAI Chat Completions, Responses API, streaming, tool calling

- Async Python - asyncio, httpx, FastAPI

- Prompt engineering - system prompts, few-shot, structured JSON output

- Circuit breaker patterns, retry logic, resilient service design

- PostgreSQL and async ORMs (SQLAlchemy async / Alembic)

- Git, CI/CD, Docker, Kubernetes basics

- Strong system design skills - microservices, distributed systems, API design

Nice-to-Have

- LangGraph StateGraph (conditional edges, node pipelines, compiled graphs)

- Multi-agent systems - orchestration, routing, RBAC-based access control

- Langfuse or similar LLM observability (tracing, token usage, latency)

- WebSocket and SSE streaming protocols

- Multi-modal AI (vision models, image analysis)

- Vector databases (OpenSearch, Pinecone, pgvector)

- AWS services (Aurora PostgreSQL, SSM, IAM, EKS)

- Telecommunications or field service domain experience

Apply