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Python Developer Jobs in Fort Myers, FL (NOW HIRING)

Sr. Software Engineer, LIMS

Fort Myers, FL · Hybrid

$114K - $150K/yr

NeoGenomics is looking for a Senior Software Engineer (LIMS) who wants to learn to continue to ... Solidexpertisein C# isrequired; experience with Java and Python frameworks is a plus. * Extensive ...

Full Stack Developer

Fort Myers, FL · On-site

$70 - $80/hr

Remote Duration: 6-9 Month Contract, Potential to Extend Rate: $70-$80 Per Hour W2 We are seeking a Senior Full Stack Developer for a transformation team. This role involves a dual focus on ...

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Python Developer information

See Fort Myers, FL salary details

$12

$54

$80

How much do python developer jobs pay per hour?

As of Sep 13, 2026, the average hourly pay for python developer in Fort Myers, FL is $54.71, according to ZipRecruiter salary data. Most workers in this role earn between $45.10 and $62.16 per hour, depending on experience, location, and employer.

What does a Python developer do?

As a Python developer, your job is to use the Python programming language to develop, implement, and debug a project. In this role, you may create an application for your employer, design the framework for your code, build tools as necessary to get the job done, create websites, or publish new services. Python developers often work with data collection and analytics to create useful answers to questions and provide insight where it's needed most. Like most programming positions, the specifics of this job vary based on the needs of your employer. Some Python developers work as independent contractors instead of being exclusive to one company.

What does a Python developer do?

A Python Developer designs, codes, and maintains software applications using the Python programming language. They often work on web applications, data analysis, automation scripts, and more. Their responsibilities can include writing and testing code, debugging programs, integrating third-party services, and collaborating with other developers and stakeholders. Python Developers are valued for their ability to create efficient, scalable, and readable code. They may also be involved in deploying applications and maintaining technical documentation.

What are the key skills and qualifications needed to thrive as a Python developer, and why are they important?

To thrive as a Python Developer, you need strong programming skills in Python, a solid understanding of algorithms and data structures, and often a degree in computer science or a related field. Familiarity with frameworks like Django or Flask, version control systems such as Git, and knowledge of databases and cloud services are commonly required. Problem-solving ability, attention to detail, and effective communication help developers collaborate and deliver high-quality code. These skills and qualities are vital to building efficient, scalable software solutions and contributing effectively to development teams.

What are some common challenges Python developers face when working on large-scale projects?

Python Developers working on large-scale projects often encounter challenges such as managing codebase complexity, ensuring consistent code style among team members, and optimizing application performance. Collaboration with other developers becomes essential, often requiring the use of version control systems and code review processes. Additionally, integrating Python code with other technologies or legacy systems can present unique compatibility and testing hurdles. Proactively adopting best practices like modular architecture and thorough documentation can help mitigate these issues.

What is the difference between Python Developer vs Java Developer?

AspectPython DeveloperJava Developer
Required CredentialsBachelor's in CS or related field, Python certifications (optional)Bachelor's in CS or related field, Java certifications (optional)
Work EnvironmentWeb development, data science, automation, scriptingEnterprise applications, Android development, backend systems
Industry UsageTech startups, data companies, automation firmsFinancial services, enterprise software, mobile app companies
Common Search/ComparisonOften compared for backend and scripting rolesCompared for enterprise and mobile app development

Python Developers and Java Developers share similar educational backgrounds and often work in backend environments. However, Python is favored for data science, scripting, and rapid development, while Java is preferred for large-scale enterprise applications and Android development. Both roles are highly sought after, but their industry focus and project types differ.

How much do Python developers get paid?

Python developers' salaries vary based on experience, location, and skill level, but they typically earn between $70,000 and $120,000 annually in the United States. Senior developers with expertise in frameworks, data analysis, or machine learning can earn higher salaries, especially in tech hubs. Entry-level positions generally start around $60,000 to $80,000.

Is Python in demand in 2026?

Python developers are expected to remain in high demand through 2026 due to the language's widespread use in data science, web development, automation, and artificial intelligence. Proficiency in frameworks like Django or Flask and knowledge of related tools can enhance job prospects in this field.

Is there a demand for Python developers?

Python developers are in high demand across various industries such as technology, finance, and data science due to Python's versatility and widespread use in web development, automation, and machine learning. Employers seek professionals with skills in frameworks like Django or Flask and knowledge of data analysis tools like Pandas and NumPy, making Python a valuable programming language for job seekers.

What jobs can a Python Developer get?

A Python Developer can work in roles such as software engineer, web developer, data analyst, data scientist, machine learning engineer, automation engineer, and backend developer. These positions often require knowledge of frameworks like Django or Flask, and familiarity with databases and version control systems.

What are the most commonly searched types of Python Developer jobs in Fort Myers, FL?

The most popular types of Python Developer jobs in Fort Myers, FL are:

What are popular job titles related to Python Developer jobs in Fort Myers, FL?

For Python Developer jobs in Fort Myers, FL, the most frequently searched job titles are:

What cities near Fort Myers, FL are hiring for Python Developer jobs?

Cities near Fort Myers, FL with the most Python Developer job openings:

Infographic showing various Python Developer job openings in Fort Myers, FL as of August 2026, with employment types broken down into 1% Internship, 82% Full Time, 12% Part Time, and 5% Contract. Highlights an 76% Physical, 7% Hybrid, and 17% Remote job distribution, with an average salary of $113,807 per year, or $54.7 per hour.

Sr. Software Engineer, LIMS

Fort Myers, FL • Hybrid

NeoGenomics
Health Care and Social Assistance • 1 - 5K employees

$114K - $150K/yr

Full-time

Medical, Retirement, PTO

Re-posted 22 days ago


Key responsibilities

  • Design, develop, test, and maintain scalable, high-performance software applications using C#, .NET Framework, and .NET Core/.NET 8+.

  • Design, configure, and maintain LIMS workflows, sample lifecycles, tests, and specifications, including supporting custom configurations, scripts, rules, and extensions.

  • Collaborate with cross-functional teams to define technical requirements, support integration of laboratory instruments, and ensure system performance, reliability, and scalability.


NeoGenomics rating

8.0

Company rating: 8.0 out of 10

Based on 34 frontline employees who took The Breakroom Quiz


Job description

Are you motivated to participate in a dynamic, multi-tasking environment? Do you want to join a company that invests in its employees? Are you seeking a position where you can use your skills while continuing to be challenged and learn? Then we encourage you to dive deeper into this opportunity.

We believe in career development and empowering our employees. Not only do we provide career coaches internally, but we offer many training opportunities to expand your knowledge base! We have highly competitive benefits with a variety HMO and PPO options. We have company 401k match along with an Employee Stock Purchase Program. We have tuition reimbursement, leadership development, and even start employees off with 16 days of paid time off plus holidays. We offer wellness courses and have highly engaged employee resource groups. Come join the Neo team and be part of our amazing World Class Culture!

NeoGenomics is looking for a Senior Software Engineer (LIMS) who wants to learn to continue to learn in order to allow our company to grow. This is a hybrid position to work out of Ramsey, NJ or Fort Myers, FL.

Now that you know what we're looking for in talent, let us tell you why you'd want to work at NeoGenomics:

As an employer, we promise to provide you with a purpose driven mission in which you have the opportunity to save lives by improving patient care through the exceptional work you perform. Together, we will become the world's leading cancer reference laboratory.

Position Summary: 

As a Senior Software Engineer (LIMS) you are responsible for supporting and advancing in-house Laboratory Information Management System (LIMS) development initiatives. This role designs, develops, reviews, and maintains application solutions while ensuring system performance, reliability, and scalability. Key responsibilities include conducting architecture and code reviews, identifying and resolving complex software defects, performing root cause analysis, and implementing performance optimization strategies. The Senior Software Engineer partners closely with Quality Assurance teams to provide technical oversight, validate code quality, and ensure adherence to development standards and best practices across existing code bases. This is a hybrid position, requiring a minimum of two days per week in the office.

Responsibilities:

  • Design, develop, test, andmaintainscalable, high-performance software applications using C#, .NET Framework, and .NET Core/.NET 8+. 
  • Architect and implement RESTful APIs, microservices, and event-driven solutions to support enterprise business applications. 
  • Collaborate with product managers, architects, QA engineers, and business stakeholders to define technical requirements and deliver high-quality solutions. 
  • Design, configure, andmaintainLIMS workflows, sample lifecycles, tests, and specifications. 
  • Develop and support custom configurations, scripts, rules, and extensions 
  • Configure andoptimizelaboratory processes such as: 
  • Sample logging and tracking 
  • Testing, results entry, review, and approval 
  • Integrate LIMS with laboratory instruments and other lab applications 

Education, Experience & Qualifications:

  • Bachelor’s Degree in Computer Science, Information Technology or a related field 
  • 7+ years of experience in software development ina .NETenvironment. 
  • Healthcare Industryand/orLaboratory Information Management Systems (LIMS) experience required 
  • Experience working within the healthcare, life sciences, or other highly regulated industries.
  • Must be authorized to work in the United States without the need for current or future employer sponsorship.
  • Solidexpertisein C# isrequired; experience with Java and Python frameworks is a plus. 
  • Extensive experience building scalable backend solutionsutilizingASP.NET Framework, RESTful services, andmicroservicesarchitecture. 
  • Proficiencyin Microsoft SQLServer;experience working with a variety of SQL and NoSQL databases is a plus. 
  • Experience with cloud platforms (AWS, Azure) 
  • Solid understanding of data structures, algorithms, and object-oriented design principles, and designing and building data models to improve accessibility, efficiency, and quality of data. 
  • Experience building andmaintainingscalable,highly available, and fault-tolerant systems 
  • Strong hands-on skills with a proven ability to improve application architecture and resolve code-level issues quickly. 
  • Ability to perform Root Cause Analysis on high-impact issues within the application. 
  • Understanding ofIT Security and Compliance audit processes. 

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