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Protocol Development Jobs (NOW HIRING)

Protocol Officer

Springfield, VA · On-site

$107K - $179K/yr

The Protocol Officer is a core member of the protocol team responsible for the detailed planning ... Coordinate end-to-end logistics for distinguished guests, including the development of detailed ...

Protocol Officer

Springfield, VA · On-site

$107K - $179K/yr

The Protocol Officer is a core member of the protocol team responsible for the detailed planning ... Coordinate end-to-end logistics for distinguished guests, including the development of detailed ...

You will also have the opportunity to participate in the protocol development, clinical development plan, strategic discussion and cross alliance discussion. This will be an associate director or ...

Develop protocols, investigator brochures, SAP inputs, and essential documents tailored for ... Work tightly with: * R&D to vet new drug targets and mechanisms and interpret pre-clinical data

Showing results 41-60

Protocol Development information

See salary details

$29K

$53.4K

$81K

How much do protocol development jobs pay per year?

As of Aug 8, 2026, the average yearly pay for protocol development in the United States is $53,418.00, according to ZipRecruiter salary data. Most workers in this role earn between $42,500.00 and $60,000.00 per year, depending on experience, location, and employer.

What is the difference between Protocol Development vs Clinical Research Associate?

AspectProtocol DevelopmentClinical Research Associate
Primary RoleDesigns and develops clinical trial protocolsMonitors clinical trials to ensure compliance and data integrity
Required SkillsKnowledge of clinical trial design, regulatory guidelines, and writing skillsMonitoring skills, regulatory knowledge, and communication skills
Work EnvironmentTypically in planning, development, and regulatory teamsOn-site or remote monitoring at clinical trial sites
CertificationsOften requires knowledge of GCP, regulatory affairsGCP certification often preferred

While Protocol Development focuses on creating and designing clinical trial protocols, Clinical Research Associates are responsible for monitoring and ensuring trial compliance at sites. Both roles are essential in clinical research but differ in their core responsibilities and work environments.

What are the key skills and qualifications needed to thrive in protocol development, and why are they important?

To thrive in Protocol Development, you need a solid background in clinical research, regulatory requirements, and scientific writing, often supported by a degree in life sciences or a related field. Familiarity with tools such as clinical trial management systems (CTMS), electronic data capture (EDC), and knowledge of ICH-GCP guidelines is typically required. Strong attention to detail, project management, and effective communication skills help professionals excel in this role. These competencies ensure the creation of clear, compliant, and scientifically sound protocols that are essential for successful clinical trials.

What is protocol development?

Protocol development refers to the process of designing and creating detailed plans, often called protocols, which outline the methodology and procedures for conducting research or clinical trials. This includes specifying objectives, study design, data collection methods, and regulatory requirements to ensure the study is scientifically valid and ethically sound. Protocol developers work closely with researchers, regulatory bodies, and stakeholders to ensure all aspects of the protocol meet industry standards and compliance guidelines.

What are the main challenges someone might face when starting in a protocol development role?

One of the main challenges in Protocol Development is quickly understanding complex technical standards and aligning them with organizational goals. New team members often need to collaborate closely with cross-functional teams, such as engineering, legal, and product management, to ensure protocols are both technically sound and compliant with industry regulations. Adapting to rapidly evolving technologies and maintaining clear documentation can also be demanding, but strong communication and a willingness to learn can help overcome these hurdles.
More about Protocol Development jobs
What cities are hiring for Protocol Development jobs? Cities with the most Protocol Development job openings:
What states have the most Protocol Development jobs? States with the most job openings for Protocol Development jobs include:
Infographic showing various Protocol Development job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 15% Part Time, and 3% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $53,418 per year, or $25.7 per hour.

Lead Protocol Engineer (Go / Cryptography)

Wells Fargo

Columbus, OH • On-site

$99K - $130K/yr

Full-time

Medical, Life, Retirement, PTO

Re-posted 26 days ago


Wells Fargo rating

7.8

Company rating: 7.8 out of 10

Based on 707 frontline employees who took The Breakroom Quiz

89th of 170 rated banks


Job description

About this Role:

Wells Fargo is seeking a Lead Specialty Software Engineer (Protocol Engineer) to contribute to a next-generation Digital Asset Platform designed to solve the most critical challenge in institutional finance: achieving strict regulatory compliance without compromising transaction confidentiality. As a Lead Protocol Engineer, you will be responsible for architecting the core settlement engine. You will work at the intersection of distributed systems and applied cryptography, translating complex mathematical proofs into high-performance, production-grade Go code.

Why Join Us?

  • Work on "Hard" Problems:You won't be building another yield farm copycat. You'll solve fundamental privacy/compliance contradictions in the global financial system

  • High-Impact Engineering:Your code will secure high-value institutional transactions

  • Technical Autonomy:You'll play a key role in architectural decisions, choosing the right curves, libraries, and design patterns

Responsibilities

  • Core Protocol Development:Architect and build a custom blockchain application usingGo,Cosmos SDK, andCometBFT (Tendermint)

  • Cryptographic Implementation:Implement and optimize privacy-preserving primitives, specificallyPedersen CommitmentsandBulletproofs (Range Proofs), ensuring no trusted setup is required

  • Consensus Customization:Engineer customABCI++extensions (specificallyPrepareProposaland Vote Extensions) to implement an on-chain Multi-Party Computation (MPC) mixing network

  • State Machine Design:Design a customKVStorestate machine that manages homomorphic encrypted balances (Elliptic Curve points) instead of plaintext integers

  • Performance Engineering:Optimize cryptographic operations (scalar multiplication, point addition) for low latency and high throughput in a distributed environment

  • Auditing Infrastructure:Build secure off-chain query layers and "view key" mechanisms that allow for granular, permissioned regulatory auditing

Required Qualifications:

  • 5+ years of Specialty Software Engineering experience, or equivalent demonstrated through one or a combination of the following: work experience, training, military experience, education

  • 3+ years of experience in backend or systems programming, with expert-level proficiency inGo (Golang)

  • 6+ months of experience with Elliptic Curve Cryptography (ECC)

  • 1+ year of experience with BFT consensus algorithms, P2P networking, and state replication; reliable, distributed systems experience

Desired Qualifications:

  • Blockchain Core:Deep experience withCosmos SDKandCometBFT. Comfort building custom modules and modifying consensus logic, not just deploying smart contracts

  • Pedersen Commitments(Homomorphic encryption properties)

  • Zero-Knowledge Proofs(specifically Bulletproofs or Sigma protocols)

  • Math-to-Code:Demonstrated ability to read academic whitepapers/preprints and translate mathematical specifications into functioning code

  • Experience withMPC (Multi-Party Computation)or Verifiable Secret Sharing (VSS) schemes

  • Familiarity with theRistretto255curve or libraries likegnark-crypto

  • Background in FinTech, payment systems, or high-frequency trading platforms

  • Understanding of theAccount Modelvs.UTXO Modeltrade-offs in privacy-preserving ledgers

Job Expectations:

  • This position offers a hybrid work schedule

  • Relocation assistance is not available for this position

Locations:

  • 194 Wood Ave S, Iselin, New Jersey

  • 3075 Loyalty Circle, Columbus, Ohio

  • 1755 Grant Street, Concord, California

    Pay Range

    Reflected is the base pay range offered for this position. Pay may vary depending on factors including but not limited to demonstrated examples of prior performance, skills, experience, or work location. Employees may also be eligible for incentive opportunities.

    $159,000.00 - $305,000.00

    Benefits

    Wells Fargo provides eligible employees with a comprehensive set of benefits, many of which are listed below. VisitBenefits - Wells Fargo Jobs for an overview of the following benefit plans and programs offered to employees.

    • Health benefits
    • 401(k) Plan
    • Paid time off
    • Disability benefits
    • Life insurance, critical illness insurance, and accident insurance
    • Parental leave
    • Critical caregiving leave
    • Discounts and savings
    • Commuter benefits
    • Tuition reimbursement
    • Scholarships for dependent children
    • Adoption reimbursement

    Posting End Date:

    2 Oct 2026

    *Job posting may come down early due to volume of applicants.

    We Value Equal Opportunity

    Wells Fargo is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other legally protected characteristic.

    Employees support our focus on building strong customer relationships balanced with a strong risk mitigating and compliance-driven culture which firmly establishes those disciplines as critical to the success of our customers and company. They are accountable for execution of all applicable risk programs (Credit, Market, Financial Crimes, Operational, Regulatory Compliance), which includes effectively following and adhering to applicable Wells Fargo policies and procedures, appropriately fulfilling risk and compliance obligations, timely and effective escalation and remediation of issues, and making sound risk decisions. There is emphasis on proactive monitoring, governance, risk identification and escalation, as well as making sound risk decisions commensurate with the business unit's risk appetite and all risk and compliance program requirements.

    Applicants with Disabilities

    To request a medical accommodation during the application or interview process, visitDisability Inclusion at Wells Fargo.

    Drug and Alcohol Policy

    Wells Fargo maintains a drug free workplace. Please see our Drug and Alcohol Policy to learn more.

    Wells Fargo Recruitment and Hiring Requirements:

    a. Third-Party recordings are prohibited unless authorized by Wells Fargo.

    b. Wells Fargo requires you to directly represent your own experiences during the recruiting and hiring process.


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    About Wells Fargo

    Sourced by ZipRecruiter

    Wells Fargo & Company (NYSE: WFC) is a leading financial services company that has approximately $1.9 trillion in assets, proudly serves one in three U.S. households and more than 10% of small businesses in the U.S., and is a leading middle market banking provider in the U.S. We provide a diversified set of banking, investment and mortgage products and services, as well as consumer and commercial finance, through our four reportable operating segments: Consumer Banking and Lending, Commercial Banking, Corporate and Investment Banking, and Wealth & Investment Management. Wells Fargo ranked No. 41 on Fortune's 2022 rankings of America's largest corporations. In the communities we serve, the company focuses its social impact on building a sustainable, inclusive future for all by supporting housing affordability, small business growth, financial health and a low-carbon economy.

    Industry

    Finance and insurance

    Company size

    10,000+ Employees

    Headquarters location

    San Francisco, CA, US

    Year founded

    1852

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