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Protocol Development Jobs (NOW HIRING)

ECOG-ACRIN MRF

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Protocol Associate/Translational Science (Oncology Studies) HYBRID

Boston, MA · On-site

$60K - $72K/yr

Support protocol development, data coordination, specimen tracking, and inventory management. * Maintain and update electronic laboratory databases, including the Sample Tracking System. * Monitor ...

Ardelyx

Vice President, Clinical Development

Newark, CA · On-site

Design and oversee clinical studies, including protocol development, medical monitoring, data interpretation, and clinical trial execution. * Develop clinical development plans aligned with Target ...

Ardelyx

Vice President, Clinical Development

Newark, CA · On-site

Design and oversee clinical studies, including protocol development, medical monitoring, data interpretation, and clinical trial execution. * Develop clinical development plans aligned with Target ...

Wells Fargo

Senior Specialty Protocol Engineer

Iselin, NJ

$106K - $145K/yr

Core Protocol Development: Architect and build a custom blockchain application using Go , Cosmos SDK , and CometBFT (Tendermint) * Cryptographic Implementation: Implement and optimize privacy ...

Wells Fargo

Senior Specialty Protocol Engineer

Concord, CA

$114K - $157K/yr

Core Protocol Development: Architect and build a custom blockchain application using Go , Cosmos SDK , and CometBFT (Tendermint) * Cryptographic Implementation: Implement and optimize privacy ...

Galaxy

Protocol Director

Identify where emerging protocol developments represent material opportunities or threats for the business. Examples would be new L1s, staking mechanisms, oracle integrations, cross-chain primitives ...

Systimmune

Clinical Development Physician

Princeton, NJ · On-site

$200K - $300K/yr

You will also have the opportunity to participate in the protocol development, clinical development plan, strategic discussion and cross alliance discussion. This will be an associate director or ...

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Protocol Development information

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$29K

$53.4K

$81K

How much do protocol development jobs pay per year?

As of Jul 17, 2026, the average yearly pay for protocol development in the United States is $53,418.00, according to ZipRecruiter salary data. Most workers in this role earn between $42,500.00 and $60,000.00 per year, depending on experience, location, and employer.

What is the difference between Protocol Development vs Clinical Research Associate?

AspectProtocol DevelopmentClinical Research Associate
Primary RoleDesigns and develops clinical trial protocolsMonitors clinical trials to ensure compliance and data integrity
Required SkillsKnowledge of clinical trial design, regulatory guidelines, and writing skillsMonitoring skills, regulatory knowledge, and communication skills
Work EnvironmentTypically in planning, development, and regulatory teamsOn-site or remote monitoring at clinical trial sites
CertificationsOften requires knowledge of GCP, regulatory affairsGCP certification often preferred

While Protocol Development focuses on creating and designing clinical trial protocols, Clinical Research Associates are responsible for monitoring and ensuring trial compliance at sites. Both roles are essential in clinical research but differ in their core responsibilities and work environments.

What are the key skills and qualifications needed to thrive in Protocol Development, and why are they important?

To thrive in Protocol Development, you need a solid background in clinical research, regulatory requirements, and scientific writing, often supported by a degree in life sciences or a related field. Familiarity with tools such as clinical trial management systems (CTMS), electronic data capture (EDC), and knowledge of ICH-GCP guidelines is typically required. Strong attention to detail, project management, and effective communication skills help professionals excel in this role. These competencies ensure the creation of clear, compliant, and scientifically sound protocols that are essential for successful clinical trials.

What is protocol development?

Protocol development refers to the process of designing and creating detailed plans, often called protocols, which outline the methodology and procedures for conducting research or clinical trials. This includes specifying objectives, study design, data collection methods, and regulatory requirements to ensure the study is scientifically valid and ethically sound. Protocol developers work closely with researchers, regulatory bodies, and stakeholders to ensure all aspects of the protocol meet industry standards and compliance guidelines.

What are the main challenges someone might face when starting in a Protocol Development role?

One of the main challenges in Protocol Development is quickly understanding complex technical standards and aligning them with organizational goals. New team members often need to collaborate closely with cross-functional teams, such as engineering, legal, and product management, to ensure protocols are both technically sound and compliant with industry regulations. Adapting to rapidly evolving technologies and maintaining clear documentation can also be demanding, but strong communication and a willingness to learn can help overcome these hurdles.
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Protocol Development jobs near you
Infographic showing various Protocol Development job openings in the United States as of July 2026, with employment types broken down into 1% As Needed, 83% Full Time, 14% Part Time, and 2% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $53,418 per year, or $25.7 per hour.

Protocol Associate/Translational Science (Oncology Studies) HYBRID

ECOG-ACRIN MRF

Boston, MA • On-site

$60K - $72K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 5 days ago

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Job description

Join a mission-driven organization dedicated to advancing cancer research and improving patient outcomes.

We are seeking a Protocol Associate to serve as the primary laboratory and data coordinator within our Translational Science Team. In this role, you will help manage laboratory projects, biospecimen activities, and research protocols while collaborating with investigators, laboratories, tissue banks, and clinical research professionals across the country.

This is an excellent opportunity for someone with oncology clinical research experience who enjoys coordinating complex projects, working with scientific data, and contributing to groundbreaking translational research.

Location: Hybrid position (Boston office with remote work flexibility)

What You'll Do

  • Coordinate laboratory activities for active and proposed translational research studies.
  • Support protocol development, data coordination, specimen tracking, and inventory management.
  • Maintain and update electronic laboratory databases, including the Sample Tracking System.
  • Monitor specimen submissions for clinical trials and retrospective tissue studies, working directly with participating research sites to resolve outstanding submissions.
  • Coordinate project related teleconferences and facilitate communication among investigators, laboratories, and other stakeholders.
  • Provide informatics support for biospecimen banking and data harmonization initiatives.
  • Support the ECOG-ACRIN Navigator concierge by serving as a liaison with tissue banks and biostatisticians to respond to requests from the NCI Navigator and Front Door systems
  • Participate in protocol development meetings, disease committee meetings, departmental meetings, and project conference calls
  • Review and maintain departmental documentation and Standard Operating Procedures (SOPs).
  • Assist with special projects and other responsibilities as assigned.

What We're Looking For

  • Bachelor's degree in a life sciences discipline or an equivalent combination of education and relevant experience.
  • Minimum of five years of oncology clinical research experience.
  • Strong organizational skills with the ability to manage multiple priorities and meet deadlines.
  • Excellent written, verbal, and interpersonal communication skills.
  • Proficiency with Microsoft Office and electronic data management systems.
  • Experience with Good Clinical Practice (GCP) guidelines is preferred.
  • Project management experience is a plus.
  • Master's degree is preferred.

Why Join Us?

  • Competitive salary of $60,000–$72,000, based on experience.
  • Hybrid work environment offering flexibility.
  • Comprehensive benefits package, including medical, dental, vision, retirement savings, and paid time off.
  • Opportunity to work alongside leading oncology researchers and make a meaningful impact on cancer research.
  • Collaborative, mission-focused culture dedicated to improving patient care through innovative clinical research.

Equal Opportunity Employer

We are committed to fostering a diverse, equitable, and inclusive workplace where every employee is valued and respected. We are proud to be an Equal Opportunity Employer and consider all qualified applicants without regard to race, color, religion, sex, national origin, age, disability, veteran status, sexual orientation, gender identity, or any other characteristic protected by applicable law.

Company Description

The ECOG-ACRIN Medical Research Foundation (EAMRF) serves as the grantee organization for the ECOG-ACRIN Cancer Research Group (Group). As a unique nonprofit organization, the overarching mission is to improve and increase patient awareness as well as facilitate access and promote participation in adult oncology clinical trials. The EAMRF provides the necessary support for EA to coordinate the scientific, administrative, governance and membership activities of the Group.
The EAMRF provides the support required to conduct oncology clinical trials. All the trials conducted under the auspices of the Group benefit public health by improving the quality and standard of care of patients with cancer. In addition, the organization promotes collaboration across the scientific community and encourages engagement of patient advocacy at all levels.