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Protein Engineering Jobs in Portland, OR (NOW HIRING)

Senior Technical Product Manager

Vancouver, WA ยท On-site

$145K - $180K/yr

Deep knowledge of bioinformatics, computational protein design, computational genomics, immunology, structural biology, antibody engineering, or related fields * Experience with NGS, SPR, or Flow ...

... protein and dry goods distribution / merchandising business โ€ข Working experience with sales techniques โ€ข Proficiency with data analysis, forecasting, and budgeting โ€ข Proven ability to plan and ...

Protein Engineering information

See Portland, OR salary details

$34.5K

$66.8K

$101.3K

How much do protein engineering jobs pay per year?

As of Sep 15, 2026, the average yearly pay for protein engineering in Portland, OR is $66,788.00, according to ZipRecruiter salary data. Most workers in this role earn between $49,800.00 and $76,400.00 per year, depending on experience, location, and employer.

What is protein engineering?

A Protein Engineering job involves designing, modifying, and optimizing proteins for specific applications in medicine, biotechnology, and industry. Scientists in this field use computational modeling, directed evolution, and genetic engineering to enhance protein functions. Roles may include developing enzymes for drug production, improving therapeutic proteins, or creating biomaterials. This work often requires expertise in molecular biology, biochemistry, and structural biology.

What are the typical daily responsibilities of someone working in protein engineering?

A typical day in Protein Engineering involves designing and conducting experiments to modify protein sequences, expressing and purifying proteins, and analyzing their structure or function using techniques like chromatography and spectroscopy. You will often document your results, troubleshoot unexpected findings, and present data to colleagues or project teams. Collaboration with scientists in molecular biology, bioinformatics, and structural biology is common to ensure robust experimental design and data interpretation. The role may also include literature reviews to stay updated with the latest research and participating in team meetings to plan next steps or project timelines.

What are the key skills and qualifications needed to thrive in protein engineering, and why are they important?

To thrive in Protein Engineering, you need a solid background in biochemistry, molecular biology, and genetic engineering, typically supported by a relevant advanced degree. Experience with laboratory techniques such as PCR, site-directed mutagenesis, protein expression/purification, and analytical tools like mass spectrometry or chromatography is essential. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills help you stand out in this role. These competencies are crucial for designing novel proteins, collaborating in multidisciplinary teams, and ensuring successful project outcomes in biotech or pharmaceutical environments.

How much do protein engineers make?

Protein engineers typically earn a median salary ranging from $70,000 to $120,000 annually, depending on experience, education, and location. Advanced skills in molecular biology, bioinformatics, and laboratory techniques can lead to higher compensation, especially in biotech or pharmaceutical industries.

What do protein engineers do?

Protein engineers design and modify proteins to improve their functions or create new ones, often using techniques like directed evolution and computational modeling. They work in research labs, utilizing tools such as gene editing and structural analysis to develop applications in medicine, agriculture, and industry.

What are the most commonly searched types of Protein Engineering jobs in Portland, OR?

The most popular types of Protein Engineering jobs in Portland, OR are:

Infographic showing various Protein Engineering job openings in Portland, OR as of September 2026, with employment types broken down into 1% Internship, 92% Full Time, 4% Part Time, 2% Contract, and 1% Nights. Highlights an 83% Physical, 4% Hybrid, and 13% Remote job distribution, with an average salary of $66,788 per year, or $32.1 per hour.

Senior Technical Product Manager

Vancouver, WA โ€ข On-site

Absci Corp.
Biotechnology Research and Developmentย โ€ขย 201 - 500 employees

$145K - $180K/yr

Other

Medical, Dental, Vision

Posted 28 days ago


Job description

About Absci

Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creationโ„ข platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets.

Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn @absci, X @Abscibio, and YouTube.

Senior Technical Product Manager (AI Research & Development)

Remote within the United States. Hybrid work available in Vancouver, WA; New York City, NY.

We are currently seeking a Senior Technical Product Manager to join our AI Research and Development team. You will be responsible for developing and executing on the vision, strategy, and deployment of both AI and Lab Products at Absci. You will drive small, interdisciplinary teams of Artificial Intelligence (AI) and Machine Learning (ML) Researchers, Software Engineers, Structural Biologists, and Screening Scientists to build delivery platforms that allow us to design, optimize, and validate biologics for treating conditions like cancer, autoimmune diseases, and infectious diseases. You will serve as a bridge between our AI Research and Biologics Discovery Technology teams, leading initiatives surrounding the development and/or application in one of two key areas:

AI-Guided Target Identification

An AI platform that leverages genetic-based evidence to discover novel target-indication pairs and de-risk in vivo or ex vivo pathway validation.

AI-Guided Drug Design

A platform that uses generative AI to design and optimize antibody-based drugs to grow Absciโ€™s internal pipeline and deliver on external partnerships.

Responsibilities:

  • Gather and synthesize product requirements from AI, Engineering, and Wet Lab Scientists and Business Development teams, then drive alignment with leadership for actionable product strategy
  • Own product roadmaps with decisive precision and bias for action; make trade-off decisions between competing priorities and risk
  • Partner with managers and technical leads with diverse backgrounds and areas of expertise to establish a cohesive product vision
  • Build detailed roadmaps, backlogs, and execution plans for assigned domain; partner with management to define OKRs and KPIs; track performance and adjust strategy based on data
  • Lead cross-functional teams through product initiatives from conception through deployment and optimization, proactively identifying and removing any blockers
  • Conduct research with product team and potential users to understand needs, pain points, and opportunities
  • Drive adoption and successful deployment of products within internal programs and external partnerships

Qualifications:

  • Bachelor's degree in Computer Science, Bioinformatics, Data Science, Engineering, Life Sciences, or related field
  • At least 5 years of professional experience working on production-grade software or technical products development
  • 3+ years of working or educational experience in AI/ML and/or Protein Engineering
  • Strong technical knowledge to enable effective collaboration with world-class engineers and scientists
  • Proven track record of creating and executing on product roadmaps to deliver high-impact work
  • Demonstrated ability to manage complex stakeholder relationships across diverse teams
  • Excellent written and oral communication skills; ability to explain complex technical and business concepts
  • Excellent organizational skills and ability to manage multiple competing priorities
  • Comfortable working in a fast-paced environment with autonomy, accountability, and bias for action

Preferred (but not required):

  • Masters or PhD degree in relevant field
  • Experience in the Biotech or Pharmaceutical Industries
  • Experience with generative AI (GenAI), NLP, or computer vision, large language models (LLMs), or protein language models
  • Experience with MLOps tools such as Weights & Biases
  • Deep knowledge of bioinformatics, computational protein design, computational genomics, immunology, structural biology, antibody engineering, or related fields
  • Experience with NGS, SPR, or Flow Cytometry data
  • Experience as an agile coach, product owner, or Scrum Master

The salary range for US-based employees in this position is $145,000 - $180,000/year. Competitive equity package applies. Pay offered may vary depending on job-related knowledge, skills, and experience. In addition to equity, compensation packages include a wide range of medical, dental, vision benefits and ability to participate in our employee stock purchase plan.

Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which they have applied should make a request to the recruiter or hiring manager, or contact hiring@absci.com.

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