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Protein Engineering Jobs in Wisconsin (NOW HIRING)

Reliability Engineer 1

Waunakee, WI · On-site

$104K - $131K/yr

JOB SUMMARY Join our team at Scientific Protein Laboratories (SPL), a world leader in biosourced ... This role combines plant-floor reliability engineering with data-driven analysis, preventive and ...

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Protein Engineering information

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$32.8K

$63.6K

$96.4K

How much do protein engineering jobs pay per year?

As of Sep 8, 2026, the average yearly pay for protein engineering in Wisconsin is $63,566.00, according to ZipRecruiter salary data. Most workers in this role earn between $47,400.00 and $72,700.00 per year, depending on experience, location, and employer.

What is protein engineering?

A Protein Engineering job involves designing, modifying, and optimizing proteins for specific applications in medicine, biotechnology, and industry. Scientists in this field use computational modeling, directed evolution, and genetic engineering to enhance protein functions. Roles may include developing enzymes for drug production, improving therapeutic proteins, or creating biomaterials. This work often requires expertise in molecular biology, biochemistry, and structural biology.

What are the typical daily responsibilities of someone working in protein engineering?

A typical day in Protein Engineering involves designing and conducting experiments to modify protein sequences, expressing and purifying proteins, and analyzing their structure or function using techniques like chromatography and spectroscopy. You will often document your results, troubleshoot unexpected findings, and present data to colleagues or project teams. Collaboration with scientists in molecular biology, bioinformatics, and structural biology is common to ensure robust experimental design and data interpretation. The role may also include literature reviews to stay updated with the latest research and participating in team meetings to plan next steps or project timelines.

What are the key skills and qualifications needed to thrive in protein engineering, and why are they important?

To thrive in Protein Engineering, you need a solid background in biochemistry, molecular biology, and genetic engineering, typically supported by a relevant advanced degree. Experience with laboratory techniques such as PCR, site-directed mutagenesis, protein expression/purification, and analytical tools like mass spectrometry or chromatography is essential. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills help you stand out in this role. These competencies are crucial for designing novel proteins, collaborating in multidisciplinary teams, and ensuring successful project outcomes in biotech or pharmaceutical environments.

How much do protein engineers make?

Protein engineers typically earn a median salary ranging from $70,000 to $120,000 annually, depending on experience, education, and location. Advanced skills in molecular biology, bioinformatics, and laboratory techniques can lead to higher compensation, especially in biotech or pharmaceutical industries.

What do protein engineers do?

Protein engineers design and modify proteins to improve their functions or create new ones, often using techniques like directed evolution and computational modeling. They work in research labs, utilizing tools such as gene editing and structural analysis to develop applications in medicine, agriculture, and industry.

What are the most commonly searched types of Protein Engineering jobs in Wisconsin?

The most popular types of Protein Engineering jobs in Wisconsin are:

What are popular job titles related to Protein Engineering jobs in Wisconsin?

For Protein Engineering jobs in Wisconsin, the most frequently searched job titles are:

Infographic showing various Protein Engineering job openings in Wisconsin as of August 2026, with employment types broken down into 91% Full Time, 5% Part Time, 3% Contract, and 1% Nights. Highlights an 85% Physical, 5% Hybrid, and 10% Remote job distribution, with an average salary of $63,566 per year, or $30.6 per hour.

$104K - $131K/yr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 12 days ago


Job description

Join our team at Scientific Protein Laboratories (SPL), a world leader in biosourced pharmaceuticals, located just outside of Madison, Wisconsin in Waunakee! SPL is an innovative biopharmaceutical leader with unique products and services supporting the pharmaceutical industry globally. For over 40 years, SPL specializes in the development and cGMP compliant manufacturing of Active Pharmaceutical Ingredients (APIs).
The primarily function of the Reliability Engineer is reliability analysis, PM optimization, failure elimination, asset lifecycle technical support. This position will also provide technical leadership to experienced mechanical maintenance technicians driving reliability initiatives into daily work. The Reliability Engineer will eliminate repeat failures and optimize maintenance strategies so that production equipment operates reliably, PM resources are focused on what matters most, and unplanned downtime is continuously reduced.
Responsibilities include:
  • Reliability analysis and failure elimination (RCA, FMEA, Bad Actor analysis)
  • PM program technical ownership (categorization, task optimization, interval management)
  • Predictive maintenance program development and oversight (vibration, thermography, oil analysis, ultrasound)
  • Asset lifecycle management (LCAM) technical support for new/modified installations
  • Direct supervision of Engineering Technicians; daily work coordination supported by 1st Shift Maintenance Supervisor
  • Identification and leadership of reliability-driven capital projects
  • Change control leadership for reliability improvements on GMP equipment
  • Own PM categorization assessments using risk-based methodology (severity, occurrence, detection); coordinate Quality-critical PM reviews with QA
  • Lead Root Cause Analysis (RCA) for significant/repeat failures; drive CAPA implementation to closure
  • Conduct FMEA on critical assets to identify failure modes and optimize PM strategies
  • Identify and manage "Bad Actors" (chronic problem equipment); develop and track elimination plans
  • Develop and refine predictive maintenance (PdM) program; analyze trends and recommend interventions before failure
  • Provide reliability input to capital projects (design reviews, acceptance criteria, commissioning plans) per LCAM process
  • Identify, propose, and lead capital projects that improve equipment reliability or eliminate chronic failure modes
  • Lead change control efforts to implement reliability improvements on GMP equipment
  • Partner with Maintenance Planning to ensure PM task content and intervals are technically sound and value-added
  • Supervise and develop Engineering Technicians; provide technical guidance on complex troubleshooting and reliability best practices
  • Provide technical support to Production, Maintenance, and other technical personnel as needed
  • Analyze CMMS data for reliability trends, downtime drivers, and improvement priorities, report findings to Maintenance, Facilities & Asset Systems Manager Utilizes good housekeeping

Job Requirements and Qualifications:
  • Experience: Required- 2+years, Preferred-10+years

  • Education: Required- Associate's degree or above in Engineering (Chemical, Electrical, Mechanical, Industrial, Reliability) or related discipline, or equivalent experience. Preferred- Bachelor's degree or above in Engineering (Chemical, Electrical, Mechanical, Industrial, Reliability) or related discipline.

Schedule:
  • 1st shift

WHY JOIN SPL?
Our employees are our success! We recruit motivated people, recognize their contributions, and support their development to reach their full potential.
Perks include: competitive compensation; excellent benefits package - including Medical, Dental and Vision on Day 1; Life and AD&D Insurance, and Short and Long-term Disability; Health and Flexible Saving Account options; Employee Assistance Program, generous vacation; paid Holidays; 401k; advancement opportunities; team-oriented environment; community involvement; company events and more!
SPL is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, color, creed, disability, gender identity, national origin, protected veteran status, race, religion, sex, sexual orientation, and any other status protected by applicable local, state or federal law.