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Protein Engineering Scientist Jobs in Minnesota (NOW HIRING)

LGC Group

Regional Account Manager

Alexandria, MN · On-site

... protein expression, PCR instruments, reagents and consumables for the extended AgBio/Applied ... across scientific operations, product management, and engineering to address complex client ...

LGC Group

Regional Account Manager

Alexandria, MN · On-site +1

... protein expression, PCR instruments, reagents and consumables for the extended AgBio/Applied ... across scientific operations, product management, and engineering to address complex client ...

University of Minnesota

Researcher 5

Minneapolis, MN

$70K - $85K/yr

Stay updated on technological and scientific advancements in the field. * Utilize a variety of ... and genetically engineered animal models. * Understand biological process models, derive ...

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All JobsProtein Engineering Scientist JobsProtein Engineering Scientist Jobs in Minnesota

Protein Engineering Scientist information

See Minnesota salary details

$39.7K

$96.7K

$153.3K

How much do protein engineering scientist jobs pay per year?

As of Sep 5, 2026, the average yearly pay for protein engineering scientist in Minnesota is $96,725.00, according to ZipRecruiter salary data. Most workers in this role earn between $76,400.00 and $113,600.00 per year, depending on experience, location, and employer.

What is a protein engineering scientist?

A Protein Engineering Scientist designs and optimizes proteins for specific applications using techniques like directed evolution and computational modeling. They work in biotechnology, pharmaceuticals, or academic research to develop enzymes, antibodies, or therapeutic proteins. Their role includes molecular biology, structural analysis, and laboratory experimentation to improve protein function, stability, or specificity.

What are the typical day-to-day responsibilities of a protein engineering scientist?

As a Protein Engineering Scientist, your daily responsibilities often include designing and executing experiments to modify protein structures, analyzing biochemical data, and troubleshooting experimental results. You’ll regularly use both laboratory techniques and computational tools to optimize protein properties, document your findings, and present data to project teams. Collaboration is a key part of the role, so you’ll frequently interact with colleagues from molecular biology, bioinformatics, and downstream process development groups. This dynamic environment keeps the work intellectually stimulating and offers ongoing opportunities to learn from multidisciplinary teams.

What are the key skills and qualifications needed to thrive as a protein engineering scientist?

To thrive as a Protein Engineering Scientist, you need a strong background in molecular biology, biochemistry, and protein design, typically demonstrated through an advanced degree (MSc or PhD) in a life science field. Experience with techniques such as site-directed mutagenesis, protein expression and purification, and familiarity with analytical tools like HPLC, mass spectrometry, and relevant bioinformatics software is essential. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills set top candidates apart. Mastery of these areas is crucial for efficiently designing, optimizing, and characterizing proteins that meet organizational and research goals.

What are the most commonly searched types of Protein Engineering Scientist jobs in Minnesota?

The most popular types of Protein Engineering Scientist jobs in Minnesota are:

What are popular job titles related to Protein Engineering Scientist jobs in Minnesota?

For Protein Engineering Scientist jobs in Minnesota, the most frequently searched job titles are:

What job categories do people searching Protein Engineering Scientist jobs in Minnesota look for?

The top searched job categories for Protein Engineering Scientist jobs in Minnesota are:

Protein Engineering Scientist jobs near you
Infographic showing various Protein Engineering Scientist job openings in Minnesota as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $96,725 per year, or $46.5 per hour.

Research Fellow - Physiology & BME - Chang lab

Mayo Clinic

Rochester, MN

$67K - $78K/yr

Full-time

Medical, Dental, Vision, Retirement

Posted 8 days ago

Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 706 frontline employees who took The Breakroom Quiz

136th of 898 rated healthcare providers

Job description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

Responsibilities

The soft matter and microfluidics group at Mayo Clinic, led by Dr. Connie Chang, is seeking a highly motivated postdoctoral researcher to develop innovative microfluidic technologies for molecular diagnostics and biomedical applications.
 

The ideal candidate will have expertise in microfluidics and/or molecular biology, with an interest in integrating molecular biology workflows into miniaturized, automated microfluidic systems. In particular, we are interested in candidates with experience in drop-based (droplet) microfluidics and the ability to perform or develop molecular biology assays within droplets.
Research areas include:


    Microfluidics and drop-based/droplet microfluidics
    Disease diagnostics and biomarker detection
    RNA, DNA, and protein detection, and quantification
    Molecular biology in droplet-based microfluidic systems
    Miniaturization and automation of molecular bioassays
    Integration of sample preparation, amplification, detection, and quantification on microfluidic platforms
    Development of novel microfluidic technologies for high-throughput and single-cell/molecular analysis
 

Candidates with experience in one or more of the following areas are particularly encouraged to apply: droplet microfluidics, molecular biology, nucleic acid amplification, RNA/DNA analysis, protein assays, molecular diagnostics, assay development, microfluidic device fabrication, or integration of biological assays with microfluidic platforms.
The position offers an opportunity to work at the interface of microfluidics, molecular biology, and biomedical diagnostics, developing new approaches for rapid, sensitive, and miniaturized molecular analysis.

Chang lab at Mayo Clinic:

    We prioritize teamwork and foster a culture of diversity, collaboration, respect, and inclusivity within a supportive laboratory environment.
    Opportunities for national and international collaborations and participation in conferences.
    Diverse and supportive work environment at the #1 hospital in the world.
    Access to state-of-the-art facilities, including advanced clinical diagnostics, BSL-2/BSL-3 laboratories, cleanrooms, core facilities: imaging, biomolecular analysis, materials characterization, division of engineering, bioinformatics, biostatistics, and specimen processing.


Contact: chang.connie@mayo.edu


Qualifications

    Ph.D. in Engineering, Physics, Chemistry, Applied Sciences
    Preferred experience in drop-based microfluidics, microfabrication, molecular biology, and/or diagnostics.
    Seeking an ambitious, curious, open-minded, and collaborative individual.
    Strong written and oral communication skills required, including technical reporting.


Exemption Status
Exempt
Compensation Detail
$67,282- $78,711/ year; Education, experience and tenure may be considered along with internal equity when job offers are extended.
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Varies
International Assignment
No
Site Description
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the 'EOE is the Law'.  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Recruiter
Amy HoffmanQualifications:

    Ph.D. in Engineering, Physics, Chemistry, Applied Sciences
    Preferred experience in drop-based microfluidics, microfabrication, molecular biology, and/or diagnostics.
    Seeking an ambitious, curious, open-minded, and collaborative individual.
    Strong written and oral communication skills required, including technical reporting.

What Mayo Clinic employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919

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