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Protein Design Jobs in Hanover, NH (NOW HIRING)

Repligen

Senior Scientist

Lebanon, NH

$115K - $145K/yr

Lead the design and optimization of next-generation affinity purification technologies for a wide ... Minimum of 5 years of hands-on experience in downstream processing and protein purification ...

Repligen Corporation

Senior Scientist

Lebanon, NH · On-site

$115K - $145K/yr

Lead the design and optimization of next-generation affinity purification technologies for a wide ... Minimum of 5 years of hands-on experience in downstream processing and protein purification ...

All JobsProtein Design JobsProtein Design Jobs in Hanover, NH

Protein Design information

See Hanover, NH salary details

$41.9K

$114.3K

$201.2K

How much do protein design jobs pay per year?

As of Aug 31, 2026, the average yearly pay for protein design in Hanover, NH is $114,305.00, according to ZipRecruiter salary data. Most workers in this role earn between $83,400.00 and $143,800.00 per year, depending on experience, location, and employer.

What is protein design?

Protein design is the process of creating new proteins or modifying existing ones to have specific functions or properties. This can involve using computational tools, laboratory techniques, or a combination of both to predict and engineer amino acid sequences that will fold into desired three-dimensional structures. Protein design is used in various fields, including medicine, biotechnology, and research, to develop novel enzymes, therapeutics, or materials. The field requires a strong understanding of biology, chemistry, and computer science to achieve successful outcomes.

What are the key skills and qualifications needed to thrive as a protein design scientist, and why are they important?

To thrive as a Protein Design Scientist, you need a strong background in molecular biology, biochemistry, and computational modeling, typically supported by an advanced degree in a relevant field. Proficiency with tools such as Rosetta, PyMOL, and molecular dynamics simulation software, as well as experience with protein expression and purification techniques, is essential. Analytical thinking, problem-solving, and effective communication are important soft skills to drive innovation and collaborate with interdisciplinary teams. These skills are crucial for designing functional proteins, troubleshooting experiments, and advancing research goals in biotechnology and pharmaceutical development.

What are some typical challenges faced by professionals in protein design, and how are they addressed within a team setting?

Professionals in protein design often encounter challenges such as predicting accurate protein folding, ensuring stability, and achieving desired biological activity. These complexities are typically addressed through close collaboration with computational biologists, structural biologists, and experimental scientists. Teams frequently hold cross-functional meetings to troubleshoot issues, share findings, and iterate on design strategies based on laboratory results. This collaborative environment helps leverage diverse expertise and accelerates the development of novel proteins with desired functions.

What is the difference between Protein Design vs Protein Engineering?

AspectProtein DesignProtein Engineering
Required CredentialsBiochemistry, Molecular Biology, BioinformaticsBiochemistry, Molecular Biology, Bioinformatics
Work EnvironmentResearch labs, biotech companies, academiaResearch labs, biotech companies, academia
Industry UsageDesigning novel proteins, drug development, synthetic biologyModifying existing proteins for improved function or stability

Protein Design focuses on creating new proteins with specific functions, often using computational methods. Protein Engineering involves modifying existing proteins to enhance or alter their properties. Both roles require similar skills and are used in research, biotech, and pharmaceutical industries, but their goals differ: one designs from scratch, the other optimizes existing proteins.

What job categories do people searching Protein Design jobs in Hanover, NH look for?

The top searched job categories for Protein Design jobs in Hanover, NH are:

Protein Design jobs near you
Infographic showing various Protein Design job openings in Hanover, NH as of August 2026, with employment types broken down into 1% As Needed, 85% Full Time, 8% Part Time, and 6% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $114,305 per year, or $55 per hour.

Senior Scientist

Repligen

Lebanon, NH

$115K - $145K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 13 days ago

Repligen rating

7.6

Company rating: 7.6 out of 10

Based on 13 frontline employees who took The Breakroom Quiz

Job description

Lead the design and optimization of next-generation affinity purification technologies for a wide range of biopharmaceutical modalities. This role combines high-throughput experimentation, data-driven process development, and cross-functional collaboration to deliver innovative purification solutions that accelerate bioprocessing performance and enable partner success.
"This role is expected to model our Leadership Behaviors-Integrity & Compliance, Customer Focus, Collaboration, Courage, Team Empowerment, and Accountability & Results-in all aspects of work."Key Responsibilities
  • Design, develop, and optimize affinity chromatography-based purification processes for diverse biopharmaceutical modalities
  • Execute high-throughput chromatographic screening and apply DOE methodologies to accelerate process development
  • Analyze, interpret, and communicate complex datasets to drive decision-making and support partner adoption of new technologies
  • Collaborate cross-functionally with internal teams (chemistry, analytics, commercial) to deliver integrated purification solutions
  • Contribute to multiple development programs, ensuring timely execution and high-quality scientific output
  • Innovate and propose novel approaches to improve purification performance, selectivity, and scalability
  • Engage with external biopharma partners as a technical expert and scientific collaborator
Qualifications
  • MS or PhD in Biochemistry, Chemical Engineering, Biochemical Engineering, or related field
  • Minimum of 5 years of hands-on experience in downstream processing and protein purification; including FPLC
  • Experience across multiple modalities (e.g., proteins, enzymes, vaccines, VLPs, gene therapy vectors)
  • Expertise in chromatography method development, including automated/high-throughput systems
  • Strong proficiency with Design of Experiments (DOE) for process optimization
  • Working knowledge of analytical techniques (e.g., purity/impurity analysis, potency, stability assays)
  • Broad scientific understanding spanning separations, protein chemistry, and bioprocessing
  • Strong communication skills with the ability to translate data into clear, actionable insights
  • Self-motivated, collaborative, and effective in a fast-paced, innovation-driven environment

Our mission is to inspire advances in bioprocessing as a trusted partner in the production of biologic drugs that improve human health worldwide. Focused on cost and process efficiencies, we deliver innovative technologies and solutions that help set new standards in bioprocessing. The estimated salary range for this role, based in the United States of America is $115,000/yr. -$145,000/yr.

Compensation decisions are dependent on several factors including, but not limited to an individual's qualifications, location, internal equity, and alignment with market data. Additionally, employees are eligible to participate in one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and flexible spending accounts. All compensation and benefits information will be confirmed in writing at the time of offer.

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