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Protein Design Jobs in Washington (NOW HIRING)

Independently initiate, plan, design, evaluate, revise and execute projects within CGE, UPLC field ... Minimum of five (5) years of experience in recombinant protein purification development for GMP ...

Senior Scientist

Gaithersburg, MD · On-site

$98K - $135K/yr

The group plays an integral part in the design and development of patient centric drug products ... Knowledge of protein biochemistry and degradation mechanisms, biopharmaceutical manufacturing ...

Biochemistry Tutor

Alexandria, VA · Remote

$18 - $40/hr

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

Biochemistry Tutor

Laurel, MD · Remote

$18 - $40/hr

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

Biochemistry Tutor

Leesburg, VA · Remote

$18 - $40/hr

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

Biochemistry Tutor

Washington, DC · Remote

$18 - $40/hr

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

Biochemistry Tutor

Fairfax, VA · Remote

$18 - $40/hr

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

Biochemistry Tutor

Bowie, MD · Remote

$18 - $40/hr

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

Biochemistry Tutor

Rockville, MD · Remote

$18 - $40/hr

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

Research Scientist

Washington, DC · On-site

$50K - $60K/yr

... the design of polymeric nanoparticles for the delivery of bioactive agents Drug-loaded ... protein analysis), LC/MS, Flow cytometry, scanning electron microscopy, transmission electron ...

DUTIES AND RESPONSIBILITIES: • Design and test new ways to leverage biochemical principals for ... protein solutions via FPLC to prepare conjugation or coating solutions. • Utilize HPLC to perform ...

Showing results 21-40

Protein Design information

What is the difference between Protein Design vs Protein Engineering?

AspectProtein DesignProtein Engineering
Required CredentialsBiochemistry, Molecular Biology, BioinformaticsBiochemistry, Molecular Biology, Bioinformatics
Work EnvironmentResearch labs, biotech companies, academiaResearch labs, biotech companies, academia
Industry UsageDesigning novel proteins, drug development, synthetic biologyModifying existing proteins for improved function or stability

Protein Design focuses on creating new proteins with specific functions, often using computational methods. Protein Engineering involves modifying existing proteins to enhance or alter their properties. Both roles require similar skills and are used in research, biotech, and pharmaceutical industries, but their goals differ: one designs from scratch, the other optimizes existing proteins.

What are some typical challenges faced by professionals in protein design, and how are they addressed within a team setting?

Professionals in protein design often encounter challenges such as predicting accurate protein folding, ensuring stability, and achieving desired biological activity. These complexities are typically addressed through close collaboration with computational biologists, structural biologists, and experimental scientists. Teams frequently hold cross-functional meetings to troubleshoot issues, share findings, and iterate on design strategies based on laboratory results. This collaborative environment helps leverage diverse expertise and accelerates the development of novel proteins with desired functions.

What are the key skills and qualifications needed to thrive as a protein design scientist, and why are they important?

To thrive as a Protein Design Scientist, you need a strong background in molecular biology, biochemistry, and computational modeling, typically supported by an advanced degree in a relevant field. Proficiency with tools such as Rosetta, PyMOL, and molecular dynamics simulation software, as well as experience with protein expression and purification techniques, is essential. Analytical thinking, problem-solving, and effective communication are important soft skills to drive innovation and collaborate with interdisciplinary teams. These skills are crucial for designing functional proteins, troubleshooting experiments, and advancing research goals in biotechnology and pharmaceutical development.

What is protein design?

Protein design is the process of creating new proteins or modifying existing ones to have specific functions or properties. This can involve using computational tools, laboratory techniques, or a combination of both to predict and engineer amino acid sequences that will fold into desired three-dimensional structures. Protein design is used in various fields, including medicine, biotechnology, and research, to develop novel enzymes, therapeutics, or materials. The field requires a strong understanding of biology, chemistry, and computer science to achieve successful outcomes.

What cities in Washington are hiring for Protein Design jobs?

Cities in Washington with the most Protein Design job openings:

Infographic showing various Protein Design job openings in Washington as of August 2026, with employment types broken down into 81% Full Time, 9% Part Time, and 10% Contract. Highlights an 96% In-person, 2% Hybrid, and 2% Remote job distribution.

Scientist - NIH VRC

Cape Fox Corporation

Bethesda, MD • On-site

$53.33/hr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 2 days ago


Job description

Job Title
Scientist - NIH VRC
Job Description
Cape Fox Facilities Services is seeking an experienced Scientist support of the overall functions of the Vaccine Research Center (VRC) on the NIH Bethesda campus by supporting collaborative research in the intramural community of the NIH.
The total hourly pay for this exempt position is $53.33 for up to 40 hours per week. This rate represents the company's good faith and reasonable estimate of possible compensation at the time of posting. In addition, for eligible positions we offer a variety of benefits including specified holidays, paid leave, health insurance, dental insurance, vision insurance, life and disability insurance, tuition reimbursement, as well as 401K with company match. This job will be posted until filled or withdrawn.
  • Participate in projects that are complex and scientifically demanding within a specific area/field, specifically Bioanalytical separation.
  • Initiate, implement, plan, and execute scientific research and development.
  • Determine scientific rigor in assessing own data and that of others, by providing detailed observations, analyzing data, and interpreting results.
  • Ensure project goals are met within time and budget constraints.
  • Independently initiate, plan, design, evaluate, revise and execute projects within CGE, UPLC field, utilizing good scientific judgment.
  • Utilize specific investigation and method development work in support of multiple projects at a time.
  • Communicate and initiate investigations for project and process findings, draw conclusions, and act as project manager in the drafting of state-of-art work and publishing of papers.
  • Develop research findings and make recommendations to leadership for decision.
  • Provide forward-looking perspectives that contribute to "go/no go" decisions by leadership.
  • Research and recommend outside technologies for consideration.

Travel Requirements
0 - 10%
Job Requirements
  • M.S degree in Chemistry, Biology, Biochemistry Life Sciences or a related discipline.
  • Minimum of five (5) years of experience in recombinant protein purification development for GMP clinical-phase products.
  • Demonstrated knowledge of maintaining accurate and detailed records.
  • Demonstrated expertise in the following techniques or tools for protein purification and characterization:
    • Column chromatography for protein purification by AEX, CEX, affinity, SEC, HIC.
    • Column packing and testing.
    • AKTA chromatography system.
    • Lab scale TFF systems.
    • Qualitative assays including SDS-PAGE and Western Blot.
    • UV/vis spectrophotometer.
    • Purification development experience for GMP process development in biotech/pharmaceutical or related industry (experience in clinical manufacturing is highly desirable).
    • Must be a team player who can effectively work with members from cross-functional departments.
    • Strong oral and written communication skills.
    • Familiarity with computer software including word processing and data evaluation.
  • Occupational Health/Physical Requirements and Worksite Hazards:
    Occupational health/physical requirements is required

Cape Fox Corporation, its subsidiaries and affiliates provide equal employment opportunities to all persons and prohibit employment decisions on the basis of race, religion, color, creed, national origin, sex, age, disability, political affiliation, protected veteran status, or sexual orientation. Cape Fox Corporation, its subsidiaries and affiliates offer preference to Cape Fox Corporation shareholders, descendants and other Native Americans pursuant to Public Law 100-241.
Category
Science / Research
Location
NIH - Bethesda, MD - Bethesda, MD 20892 US (Primary)
Education
Master's Degree