Expertise in bispecific or multispecific protein design, expression, purification, and biophysical characterization * Strong communication, data interpretation, and cross-functional collaboration ...
Expertise in bispecific or multispecific protein design, expression, purification, and biophysical characterization * Strong communication, data interpretation, and cross-functional collaboration ...
Scientist II, LC Development, Biologics Analytical Development
New Haven, CT · On-site
$80 - $110/hr
Experience with LC‑MS-based protein characterization, including intact mass and peptide mapping using high‑resolution MS platforms (e.g., Orbitrap, Q‑TOF). * Experience independently generating ...
Scientist II, LC Development, Biologics Analytical Development
New Haven, CT · On-site
$80 - $110/hr
Experience with LC‑MS-based protein characterization, including intact mass and peptide mapping using high‑resolution MS platforms (e.g., Orbitrap, Q‑TOF). * Experience independently generating ...
Experience with LCMS-based protein characterization, including intact mass and peptide mapping using highresolution MS platforms (e.g., Orbitrap, QTOF). * Experience independently generating ...
Experience with LCMS-based protein characterization, including intact mass and peptide mapping using highresolution MS platforms (e.g., Orbitrap, QTOF). * Experience independently generating ...
Senior Scientist
$90K - $123K/yr
Expertise in protein design, expression, purification, and biophysical characterization * Deep experience with bispecific or multispecific formats and familiarity with T cell engagers * Working ...
Senior Scientist
$90K - $123K/yr
Expertise in protein design, expression, purification, and biophysical characterization * Deep experience with bispecific or multispecific formats and familiarity with T cell engagers * Working ...
Senior Scientist (Branford, CT)
Branford, CT · On-site
$90K - $123K/yr
Expertise in protein design, expression, purification, and biophysical characterization * Deep experience with bispecific or multispecific formats and familiarity with T cell engagers * Working ...
Senior Scientist (Branford, CT)
Branford, CT · On-site
$90K - $123K/yr
Expertise in protein design, expression, purification, and biophysical characterization * Deep experience with bispecific or multispecific formats and familiarity with T cell engagers * Working ...
Senior Scientist (Branford, CT)
Branford, CT · On-site
$90K - $123K/yr
... in protein design, expression, purification, and biophysical characterization Deep experience with bispecific or multispecific formats and familiarity with T cell engagers Working knowledge of ...
Senior Scientist (Branford, CT)
Branford, CT · On-site
$90K - $123K/yr
... in protein design, expression, purification, and biophysical characterization Deep experience with bispecific or multispecific formats and familiarity with T cell engagers Working knowledge of ...
Lab Technician
Groton, CT · On-site
$28/hr
Characterization of proteins using SDS-PAGE and other analytical techniques. * Protein expression and/or molecular biology support Biochemical assays. Additional Information $28/hr 12 MONTHS
Lab Technician
Groton, CT · On-site
$28/hr
Characterization of proteins using SDS-PAGE and other analytical techniques. * Protein expression and/or molecular biology support Biochemical assays. Additional Information $28/hr 12 MONTHS
Senior Research Scientist, High Content Imaging
Groton, CT · On-site
$97K - $124K/yr
... characterization of our small molecules and has teams focused on high-throughput screening, DNA-encoded libraries, pharmacology, protein homeostasis platforms, cellular models, functional genomics ...
Senior Research Scientist, High Content Imaging
Groton, CT · On-site
$97K - $124K/yr
... characterization of our small molecules and has teams focused on high-throughput screening, DNA-encoded libraries, pharmacology, protein homeostasis platforms, cellular models, functional genomics ...
Senior Research Scientist, High Content Imaging
Groton, CT · On-site
$97K - $124K/yr
... characterization of our small molecules and has teams focused on high-throughput screening, DNA-encoded libraries, pharmacology, protein homeostasis platforms, cellular models, functional genomics ...
Senior Research Scientist, High Content Imaging
Groton, CT · On-site
$97K - $124K/yr
... characterization of our small molecules and has teams focused on high-throughput screening, DNA-encoded libraries, pharmacology, protein homeostasis platforms, cellular models, functional genomics ...
This position will also support other analytical method development pertaining to characterization ... Experience in (U)HPLC and practical knowledge of method development and optimization for protein ...
This position will also support other analytical method development pertaining to characterization ... Experience in (U)HPLC and practical knowledge of method development and optimization for protein ...
... DNA, residual Protein A) * Compendia method experience emphasizing USP, EP and JP compliance ... Experience in extended characterization and comparability including forced degradation studies for ...
... DNA, residual Protein A) * Compendia method experience emphasizing USP, EP and JP compliance ... Experience in extended characterization and comparability including forced degradation studies for ...
... DNA, residual Protein A) * Compendia method experience emphasizing USP, EP and JP compliance ... Experience in extended characterization and comparability including forced degradation studies for ...
... DNA, residual Protein A) * Compendia method experience emphasizing USP, EP and JP compliance ... Experience in extended characterization and comparability including forced degradation studies for ...
... residual Protein A) * Compendia method experience with a focus on USP, EP and JP compliance ... Experience in extended characterization and comparability including forced degradation studies for ...
... residual Protein A) * Compendia method experience with a focus on USP, EP and JP compliance ... Experience in extended characterization and comparability including forced degradation studies for ...
This position will also support other analytical method development pertaining to characterization ... Experience in (U)HPLC and practical knowledge of method development and optimization for protein ...
This position will also support other analytical method development pertaining to characterization ... Experience in (U)HPLC and practical knowledge of method development and optimization for protein ...
Senior Scientist Mass Spectrometrist
Groton, CT · On-site
$93K - $156K/yr
The team is responsible for the characterization of drug candidates, degradation products, and ... Protein Metrics. * Ability to work independently in problem-solving and research. * Experience ...
Senior Scientist Mass Spectrometrist
Groton, CT · On-site
$93K - $156K/yr
The team is responsible for the characterization of drug candidates, degradation products, and ... Protein Metrics. * Ability to work independently in problem-solving and research. * Experience ...
Senior Scientist Mass Spectrometrist
$93K - $156K/yr
The team is responsible for the characterization of drug candidates, degradation products, and ... Protein Metrics. * Ability to work independently in problem-solving and research. * Experience ...
Senior Scientist Mass Spectrometrist
$93K - $156K/yr
The team is responsible for the characterization of drug candidates, degradation products, and ... Protein Metrics. * Ability to work independently in problem-solving and research. * Experience ...
This position will also support other analytical method development pertaining to characterization ... Experience in (U)HPLC and practical knowledge of method development and optimization for protein ...
This position will also support other analytical method development pertaining to characterization ... Experience in (U)HPLC and practical knowledge of method development and optimization for protein ...
Protein Characterization information
See Connecticut salary details
$95.8K is the 25th percentile. Wages below this are outliers.
$94.7K - $97.2K
56% of jobs
$97.2K - $99.8K
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$115.4K - $118K
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$121.7K is the 75th percentile. Wages above this are outliers.
$120.6K - $123.2K
44% of jobs
$94.7K
$109.9K
$123.2K
How much do protein characterization jobs pay per year?
What is a protein characterization?
A Protein Characterization job involves analyzing the physical, chemical, and structural properties of proteins to understand their function, stability, and interactions. Scientists in this role use techniques like chromatography, mass spectrometry, spectroscopy, and electrophoresis to assess protein purity, folding, and activity. This work is essential in drug development, biotechnology, and academic research to ensure proteins are properly identified and function as intended.
What does a protein characterization specialist do?
As a protein characterization specialist, your daily work often involves designing and performing experiments to analyze protein structure, purity, and function using techniques like mass spectrometry, SDS-PAGE, and chromatography. You may also be responsible for preparing sample reports, maintaining laboratory instruments, and documenting results in accordance with regulatory standards. Collaboration with research scientists, quality control teams, or process development colleagues is common to ensure seamless integration of findings into larger projects. These activities require a methodical approach and a knack for troubleshooting technical challenges. Over time, you'll contribute to the development of new products or therapies and gain experience that can lead to advanced technical or supervisory roles.
What are the key skills and qualifications needed to thrive in protein characterization?
To excel in Protein Characterization, a strong background in biochemistry, molecular biology, and analytical techniques is essential, typically supported by a relevant degree (B.S., M.S., or Ph.D.). Familiarity with mass spectrometry, HPLC, electrophoresis, and software such as Microsoft Excel or specialized analysis tools is often required. Attention to detail, analytical thinking, and effective communication skills help set top performers apart in this field. Mastery of these abilities ensures accurate interpretation of complex data and effective collaboration within research or development teams.
What does protein characterization mean?
What are popular job titles related to Protein Characterization jobs in Connecticut?
For Protein Characterization jobs in Connecticut, the most frequently searched job titles are:
What job categories do people searching Protein Characterization jobs in Connecticut look for?
The top searched job categories for Protein Characterization jobs in Connecticut are:

Principal Scientist - Antibody Discovery/Protein Design
Branford, CT • On-site
Full-time
PTO
Re-posted 23 days ago
Job description
Join a company where your science will directly shape the future of cancer immunotherapy
Who We Are
EvolveImmune Therapeutics is a privately-held, next-generation immuno-oncology company pioneering a new class of T cell engager therapies to transform cancer patient outcomes compared to current immunotherapies. Our first-in-category biotherapeutic EVOLVE platform utilizes integrated T cell costimulation to directly target tumor cells to deliver durable anti-tumor adaptive immune responses. Our lead asset, EVOLVE104, entered clinical trials in late 2025. Additional collaboration pipeline programs (with Abbvie) and wholly owned programs are progressing toward candidate nomination. EvolveImmune’s team consists of ~50 FTEs in R&D, business development, people & culture, finance and operations. Our newly expanded, state-of-the-art 20,000+ square foot laboratory and office space located in the New Haven, CT biotechnology corridor is convenient to the amenities of the Connecticut shoreline, the city of New Haven and easy travel options throughout the Boston/New York City corridor.
We're hiring a Principal Scientist to join our Biotherapeutics group focused on designing and advancing first-in-class immune-engaging biologics. If you’re a protein engineer with expertise in computational protein design with experimental experience in protein discovery and optimization through antibody display technologies with an interest in advancing drug candidate toward first-in-patient evaluation, this role offers real opportunity, purpose, and scientific challenge.
What You’ll Work on
- Design and optimize novel antibody-based multispecifics targeting domains using AI/ML-model-based de novo sequence discovery
- Lead antibody engineering and antibody display-based screening from idea to experimental execution including screening, hit prioritization, and initial characterization.
- Optimize developability in lead optimization through computational and biophysical insights
- Expand company computational protein design tools and capabilities
- Collaborate across functional teams to support candidate selection and preclinical development
- Present findings in a clear, compelling way to multidisciplinary teams
- Mentor junior scientists and help shape our growing discovery efforts
_______________________________________
What You Bring
- PhD in biochemistry, computational biology, or structural biology, and postdoctoral fellowship in a related field with 5+ years of antibody and biotherapeutic engineering industry experience
- Foundation in protein design and molecular modeling using AI/ML
- Yeast or alternative antibody display technologies experience from design through screening
- Expertise in bispecific or multispecific protein design, expression, purification, and biophysical characterization
- Strong communication, data interpretation, and cross-functional collaboration skills
________________________________________
What You’ll Gain
- A hands-on, high-impact role shaping the design of next-generation immunotherapies
- Opportunity to see your work move rapidly from concept to clinic
- A visible position within the Biotherapeutics team, contributing directly to platform and pipeline innovation
- A chance to collaborate across disciplines and influence key program decisions
- Professional growth through exposure to diverse scientific challenges and cross-functional projects
- Optional mentorship opportunities and the ability to help shape a growing discovery organization
- A mission-driven, fast-paced biotech environment that values bold thinking and scientific excellence
- A supportive, open culture built on collaboration, trust, and shared purpose
________________________________________
Why You’ll Love Working Here
• Direct impact: Your science will influence platform design and shape next-generation clinical programs.
• Cutting-edge science: Help pioneer new approaches to T cell redirection in solid tumors.
• Personal growth: Gain exposure to every stage of early discovery in a collaborative biotech setting.
• Collaborative culture: Join a supportive, curious, and driven team aligned around scientific innovation and patient outcomes.
• Top-tier facilities: Work in a brand-new, purpose-built lab and office space near New Haven, CT.
• Mission with meaning: Join a company working to give more patients real hope in the fight against cancer.
________________________________________
Additional Info
• This is a full-time, onsite position based in Branford, CT
• EvolveImmune requires COVID-19 vaccination; medical and religious accommodations will be considered
• We offer competitive salary, benefits, equity, and paid time off
• We are an equal opportunity employer and value diverse perspectives in all aspects of our work
• Learn more about our science and our team at www.evolveimmune.com
________________________________________
Search Keywords
Antibody Engineering | Yeast/phage Display Technologies | AI/ML Protein Design tools | Bispecific Antibodies | Protein Engineering | Biotherapeutics | Biologics Development | T Cell Engager | Branford Biotech Jobs | Scientist Antibody Discovery | Immunotherapy Careers | Cancer Biotech | Molecular Biology | Biotech Scientist CT | New Haven Biotech | Oncology Drug Discovery | EvolveImmune Careers
About EvolveImmune Therapeutics
Sourced by ZipRecruiter
Industry
Biotechnology research and development
Company size
1 - 10 Employees
Headquarters location
Branford, CT, US
Year founded
2020