Expertise in bispecific or multispecific protein design, expression, purification, and biophysical characterization * Strong communication, data interpretation, and cross-functional collaboration ...
Quick apply
Expertise in bispecific or multispecific protein design, expression, purification, and biophysical characterization * Strong communication, data interpretation, and cross-functional collaboration ...
Quick apply
Expertise in bispecific or multispecific protein design, expression, purification, and biophysical characterization * Strong communication, data interpretation, and cross-functional collaboration ...
Experience with LC-MS-based protein characterization, including intact mass and peptide mapping using high-resolution MS platforms (e.g., Orbitrap, Q-TOF). * Experience independently generating ...
Experience with LC-MS-based protein characterization, including intact mass and peptide mapping using high-resolution MS platforms (e.g., Orbitrap, Q-TOF). * Experience independently generating ...
Experience with LCMS-based protein characterization, including intact mass and peptide mapping using highresolution MS platforms (e.g., Orbitrap, QTOF). * Experience independently generating ...
Experience with LCMS-based protein characterization, including intact mass and peptide mapping using highresolution MS platforms (e.g., Orbitrap, QTOF). * Experience independently generating ...
Branford, CT ยท On-site
$90K - $123K/yr
Expertise in protein design, expression, purification, and biophysical characterization * Deep experience with bispecific or multispecific formats and familiarity with T cell engagers * Working ...
Branford, CT ยท On-site
$90K - $123K/yr
Expertise in protein design, expression, purification, and biophysical characterization * Deep experience with bispecific or multispecific formats and familiarity with T cell engagers * Working ...
Branford, CT ยท On-site
$90K - $123K/yr
Expertise in protein design, expression, purification, and biophysical characterization * Deep experience with bispecific or multispecific formats and familiarity with T cell engagers * Working ...
Branford, CT ยท On-site
$90K - $123K/yr
Expertise in protein design, expression, purification, and biophysical characterization * Deep experience with bispecific or multispecific formats and familiarity with T cell engagers * Working ...
$90K - $123K/yr
... in protein design, expression, purification, and biophysical characterization Deep experience with bispecific or multispecific formats and familiarity with T cell engagers Working knowledge of ...
$90K - $123K/yr
... in protein design, expression, purification, and biophysical characterization Deep experience with bispecific or multispecific formats and familiarity with T cell engagers Working knowledge of ...
$28/hr
Characterization of proteins using SDS-PAGE and other analytical techniques. * Protein expression and/or molecular biology support Biochemical assays. Additional Information $28/hr 12 MONTHS
$28/hr
Characterization of proteins using SDS-PAGE and other analytical techniques. * Protein expression and/or molecular biology support Biochemical assays. Additional Information $28/hr 12 MONTHS
Execute drug development studies including physico-chemical characterization and stability studies ... Scientific and practical knowledge of protein/peptide biochemistry, protein formulation, and ...
Execute drug development studies including physico-chemical characterization and stability studies ... Scientific and practical knowledge of protein/peptide biochemistry, protein formulation, and ...
Groton, CT ยท On-site
$97K - $124K/yr
... characterization of our small molecules and has teams focused on high-throughput screening, DNA-encoded libraries, pharmacology, protein homeostasis platforms, cellular models, functional genomics ...
Groton, CT ยท On-site
$97K - $124K/yr
... characterization of our small molecules and has teams focused on high-throughput screening, DNA-encoded libraries, pharmacology, protein homeostasis platforms, cellular models, functional genomics ...
New Haven, CT ยท On-site
$234K - $245K/yr
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods. Preferred Qualifications:
New Haven, CT ยท On-site
$234K - $245K/yr
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods. Preferred Qualifications:
New Haven, CT ยท On-site
$234K - $245K/yr
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods. Preferred Qualifications:
New Haven, CT ยท On-site
$234K - $245K/yr
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods. Preferred Qualifications:
New Haven, CT ยท On-site
$234K - $245K/yr
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods. Preferred Qualifications:
New Haven, CT ยท On-site
$234K - $245K/yr
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods. Preferred Qualifications:
New Haven, CT ยท On-site
$120 - $160/hr
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods. Preferred Qualifications:
New
New Haven, CT ยท On-site
$120 - $160/hr
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods. Preferred Qualifications:
New
New Haven, CT ยท On-site
$180 - $240/hr
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods.## Preferred Qualifications:
New Haven, CT ยท On-site
$180 - $240/hr
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods.## Preferred Qualifications:
New Haven, CT ยท On-site
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods.## Preferred Qualifications:
New Haven, CT ยท On-site
The Associate Director will lead the development, characterization, technology transfer, and ... Familiarity with protein formulation, stability, and analytical methods.## Preferred Qualifications:
New Haven, CT ยท On-site
... characterization methods for Alexion| AstraZeneca Rare Disease biotherapeutic candidates. The ... Protein A, residual HCP, resDNA), potency/activity binding assays and compendial testing for in ...
New Haven, CT ยท On-site
... characterization methods for Alexion| AstraZeneca Rare Disease biotherapeutic candidates. The ... Protein A, residual HCP, resDNA), potency/activity binding assays and compendial testing for in ...
New Haven, CT ยท On-site
... characterization methods for Alexion| AstraZeneca Rare Disease biotherapeutic candidates. The ... Protein A, residual HCP, resDNA), potency/activity binding assays and compendial testing for in ...
New Haven, CT ยท On-site
... characterization methods for Alexion| AstraZeneca Rare Disease biotherapeutic candidates. The ... Protein A, residual HCP, resDNA), potency/activity binding assays and compendial testing for in ...
... characterization methods for Alexion| AstraZeneca Rare Disease biotherapeutic candidates. The ... Protein A, residual HCP, resDNA), potency/activity binding assays and compendial testing for in ...
... characterization methods for Alexion| AstraZeneca Rare Disease biotherapeutic candidates. The ... Protein A, residual HCP, resDNA), potency/activity binding assays and compendial testing for in ...
... residual Protein A) * Compendia method experience with a focus on USP, EP and JP compliance ... Experience in extended characterization and comparability including forced degradation studies for ...
... residual Protein A) * Compendia method experience with a focus on USP, EP and JP compliance ... Experience in extended characterization and comparability including forced degradation studies for ...
... DNA, residual Protein A) * Compendia method experience emphasizing USP, EP and JP compliance ... Experience in extended characterization and comparability including forced degradation studies for ...
... DNA, residual Protein A) * Compendia method experience emphasizing USP, EP and JP compliance ... Experience in extended characterization and comparability including forced degradation studies for ...
$95.8K is the 25th percentile. Wages below this are outliers.
$94.7K - $97.2K
56% of jobs
$97.2K - $99.8K
0% of jobs
$99.8K - $102.4K
0% of jobs
$102.4K - $105K
0% of jobs
$105K - $107.6K
0% of jobs
$107.6K - $110.2K
0% of jobs
$110.2K - $112.8K
0% of jobs
$112.8K - $115.4K
0% of jobs
$115.4K - $118K
0% of jobs
$118K - $120.6K
0% of jobs
$121.7K is the 75th percentile. Wages above this are outliers.
$120.6K - $123.2K
44% of jobs
$94.7K
$109.9K
$123.2K
A Protein Characterization job involves analyzing the physical, chemical, and structural properties of proteins to understand their function, stability, and interactions. Scientists in this role use techniques like chromatography, mass spectrometry, spectroscopy, and electrophoresis to assess protein purity, folding, and activity. This work is essential in drug development, biotechnology, and academic research to ensure proteins are properly identified and function as intended.
As a protein characterization specialist, your daily work often involves designing and performing experiments to analyze protein structure, purity, and function using techniques like mass spectrometry, SDS-PAGE, and chromatography. You may also be responsible for preparing sample reports, maintaining laboratory instruments, and documenting results in accordance with regulatory standards. Collaboration with research scientists, quality control teams, or process development colleagues is common to ensure seamless integration of findings into larger projects. These activities require a methodical approach and a knack for troubleshooting technical challenges. Over time, you'll contribute to the development of new products or therapies and gain experience that can lead to advanced technical or supervisory roles.
To excel in Protein Characterization, a strong background in biochemistry, molecular biology, and analytical techniques is essential, typically supported by a relevant degree (B.S., M.S., or Ph.D.). Familiarity with mass spectrometry, HPLC, electrophoresis, and software such as Microsoft Excel or specialized analysis tools is often required. Attention to detail, analytical thinking, and effective communication skills help set top performers apart in this field. Mastery of these abilities ensures accurate interpretation of complex data and effective collaboration within research or development teams.

Branford, CT โข On-site
Full-time
PTO
Re-posted 2 days ago
Join a company where your science will directly shape the future of cancer immunotherapy
Who We Are
EvolveImmune Therapeutics is a privately-held, next-generation immuno-oncology company pioneering a new class of T cell engager therapies to transform cancer patient outcomes compared to current immunotherapies. Our first-in-category biotherapeutic EVOLVE platform utilizes integrated T cell costimulation to directly target tumor cells to deliver durable anti-tumor adaptive immune responses. Our lead asset, EVOLVE104, entered clinical trials in late 2025. Additional collaboration pipeline programs (with Abbvie) and wholly owned programs are progressing toward candidate nomination. EvolveImmune’s team consists of ~50 FTEs in R&D, business development, people & culture, finance and operations. Our newly expanded, state-of-the-art 20,000+ square foot laboratory and office space located in the New Haven, CT biotechnology corridor is convenient to the amenities of the Connecticut shoreline, the city of New Haven and easy travel options throughout the Boston/New York City corridor.
We're hiring a Principal Scientist to join our Biotherapeutics group focused on designing and advancing first-in-class immune-engaging biologics. If you’re a protein engineer with expertise in computational protein design with experimental experience in protein discovery and optimization through antibody display technologies with an interest in advancing drug candidate toward first-in-patient evaluation, this role offers real opportunity, purpose, and scientific challenge.
What You’ll Work on
_______________________________________
What You Bring
________________________________________
What You’ll Gain
________________________________________
Why You’ll Love Working Here
• Direct impact: Your science will influence platform design and shape next-generation clinical programs.
• Cutting-edge science: Help pioneer new approaches to T cell redirection in solid tumors.
• Personal growth: Gain exposure to every stage of early discovery in a collaborative biotech setting.
• Collaborative culture: Join a supportive, curious, and driven team aligned around scientific innovation and patient outcomes.
• Top-tier facilities: Work in a brand-new, purpose-built lab and office space near New Haven, CT.
• Mission with meaning: Join a company working to give more patients real hope in the fight against cancer.
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Additional Info
• This is a full-time, onsite position based in Branford, CT
• EvolveImmune requires COVID-19 vaccination; medical and religious accommodations will be considered
• We offer competitive salary, benefits, equity, and paid time off
• We are an equal opportunity employer and value diverse perspectives in all aspects of our work
• Learn more about our science and our team at www.evolveimmune.com
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Search Keywords
Antibody Engineering | Yeast/phage Display Technologies | AI/ML Protein Design tools | Bispecific Antibodies | Protein Engineering | Biotherapeutics | Biologics Development | T Cell Engager | Branford Biotech Jobs | Scientist Antibody Discovery | Immunotherapy Careers | Cancer Biotech | Molecular Biology | Biotech Scientist CT | New Haven Biotech | Oncology Drug Discovery | EvolveImmune Careers
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Biotechnology research and development
1 - 10 Employees
Branford, CT, US
2020