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Protein Biophysics Jobs in Washington (NOW HIRING)

Analysis of nucleic acid and protein biophysics, computational biology models, information-theoretic measures of network connectivity, computational bioinformatics models, and neurobiological systems ...

Senior Scientist

Gaithersburg, MD · On-site

$98K - $135K/yr

Knowledge of protein biochemistry and degradation mechanisms, biopharmaceutical manufacturing processes, combination drug products, and/or biophysical analytical methods is required. * Hands-on ...

Associate Scientist

Gaithersburg, MD · On-site

$65K - $108K/yr

Hands-on experience in one or more of the following: protein or vaccine formulation, protein or vaccine stability, biophysical characterization, or bioanalytical development * Hands-on experience ...

Protein Biophysics information

See Washington salary details

$12

$45

$86

How much do protein biophysics jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for protein biophysics in Washington is $45.94, according to ZipRecruiter salary data. Most workers in this role earn between $29.94 and $54.46 per hour, depending on experience, location, and employer.

What is protein biophysics?

Protein biophysics is a scientific discipline that studies the physical principles and mechanisms underlying the structure, function, dynamics, and interactions of proteins. Researchers in this field use techniques from physics, chemistry, and biology to understand how proteins fold, move, and perform their biological roles. Methods such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and cryo-electron microscopy are commonly used to investigate protein properties. This knowledge is essential for drug discovery, understanding diseases, and developing new biomaterials.

What are the key skills and qualifications needed to thrive as a protein biophysicist, and why are they important?

To thrive as a Protein Biophysicist, you need a solid background in biology, chemistry, physics, and mathematics, typically with at least a master's or PhD in a related field. Familiarity with tools and techniques such as X-ray crystallography, NMR spectroscopy, mass spectrometry, and computational modeling software is essential. Strong analytical thinking, attention to detail, and effective collaboration and communication skills distinguish successful professionals in this role. These skills ensure accurate experimental design, data interpretation, and the ability to work efficiently within research teams to advance scientific understanding of protein structure and function.

What are some common challenges faced by professionals in protein biophysics, and how can they be addressed?

Protein biophysicists frequently encounter challenges such as interpreting complex experimental data, maintaining reproducibility in experiments, and managing interdisciplinary collaboration with chemists, biologists, and computational scientists. Staying current with rapidly evolving techniques, such as cryo-EM and single-molecule spectroscopy, is also essential. Addressing these challenges often involves continuous professional development, leveraging collaborative research environments, and utilizing advanced data analysis tools to ensure robust and accurate results.

What is the difference between Protein Biophysics vs Structural Biologist?

AspectProtein BiophysicsStructural Biologist
Required CredentialsDegree in Biochemistry, Biophysics, or related field; often PhDDegree in Structural Biology, Biochemistry, or related; often PhD
Work EnvironmentResearch labs, biotech companies, academiaResearch labs, pharmaceutical companies, academia
Industry UsageStudying protein properties, interactions, dynamicsDetermining 3D structures of proteins, complexes
Common Search/ComparisonProtein Biophysics vs Structural Biologist

Protein Biophysics focuses on understanding the physical properties and behaviors of proteins, such as stability and interactions. Structural Biologists primarily determine the 3D structures of proteins to understand their function. While both roles require advanced degrees and work in research environments, Protein Biophysics emphasizes biophysical techniques, whereas Structural Biology centers on structural determination methods like X-ray crystallography and cryo-EM.

Are protein biophysicists in demand?

Protein biophysicists are in demand in research institutions, pharmaceutical companies, and biotech firms due to their expertise in understanding protein structure and dynamics. Skills in techniques like spectroscopy, microscopy, and computational modeling increase employability, and demand is expected to grow with advances in drug development and personalized medicine.

Do protein biophysicists make good money?

Protein biophysicists typically earn competitive salaries that vary based on experience, education, and location. Entry-level positions may start around $60,000 annually, while experienced professionals or those in senior roles can earn over $100,000. Skills in laboratory techniques, data analysis, and relevant certifications can influence earning potential.

Who hires protein biophysicists?

Protein biophysicists are typically hired by pharmaceutical companies, biotechnology firms, research institutions, and academic laboratories. They work in environments that require expertise in techniques like spectroscopy, microscopy, and molecular modeling to study protein structure and function.
Infographic showing various Protein Biophysics job openings in Washington as of August 2026, with employment types broken down into 79% Full Time, 12% Part Time, 2% Temporary, 6% Contract, and 1% Nights. Highlights an 85% Physical, 1% Hybrid, and 14% Remote job distribution, with an average salary of $95,557 per year, or $45.9 per hour.

Scientist- Protein Formulation Development

MyGradJob

Gaithersburg, MD

Full-time

Re-posted 20 days ago


Key responsibilities

  • Support formulation development activities of monoclonal antibodies and novel protein-based molecules, including stability testing and characterization of degradation routes.

  • Perform laboratory activities such as buffer and protein solution preparation, pipetting, aseptic operations, and data documentation.

  • Analyze data, interpret results, and present findings at team and department meetings.


Job description

Company Description

MedImmune - Biotechnology Leader

Job Description

http://mygradjob.com/job/rd-associate-iii-protein-formulation-development-2/  APPLY HERE!


This position can be filled at either the R&D Associate I or II level depending upon experience.This position is a hands-on, laboratory-based role that supports formulation development activities of monoclonal antibodies and novel protein-based molecules. Formulation development activities include stability testing and characterization of routes of degradation of proteins in liquid and lyophilized formulations under accelerated temperature and refrigerated storage conditions and under agitation and freeze-thaw stresses in a variety of containers. Laboratory activities include buffer and protein solution preparation, pipetting and aseptic operations in a biosafety cabinet. Analytical methods that are used routinely include HPLC (reversed-phase, size-exclusion, and ion-exchange chromatography), UV-visible spectroscopy, HIAC and MicroFlow Imaging for sub-visible particle counting. Biophysical instrumentation (differential scanning calorimetry, titration calorimetry, fluorescence, circular dichroism) will occasionally be used for protein structural characterization. Activities in support of Drug Product manufacturing may be performed, which include mixing studies, process robustness and tech transfer activities.The candidate will work under general supervision and his/her work will be reviewed for accuracy and soundness of technical approach. The candidate will make detailed observations, summarize results in tables and figures, document data into lab notebooks, and analyze data and interpret results. Candidate will be expected to present data and results at group and department meetings as well as other internal forums. The individual should be familiar with general laboratory techniques and must be able to perform basic calculations.
A successful candidate will join a fast-paced and collaborative work environment where he or she will learn cutting-edge techniques and further develop his or her scientific abilities under the supervision of highly trained and experienced scientists. He or she will become part of a scientifically driven team in a world class biotechnology company committed to bringing important new medicines to patients.

Qualifications

BS in Chemistry, Biochemistry, Pharmaceutical Sciences with 0-2 years of experience of laboratory based experience

R&D Associate II

BS in Chemistry, Biochemistry, Pharmaceutical Sciences with 2-5 years of experience of laboratory based experience

MS in Chemistry, Biochemistry, Pharmaceutical Sciences of experience with 0-2 years of laboratory based experience

Preferred Skills:Prior experience working with proteins is a plus. Candidate must be able to perform independent laboratory work and effectively apply chemistry, biochemistry and pharmaceutical knowledge and principles to the design and execution of laboratory experiments. Candidate will be expected to contribute to or provide solutions to technical problems and think creatively. Experience with protein/peptide formulation, lyophilization and characterization are a plus. Additional experience with the above biophysical techniques is a plus but not required. Prior lab experience with SEC, UV-vis spectroscopy, HPLC are a plus. This is a laboratory-based position and the candidate must be familiar with basic laboratory operations (weighing chemicals, balance operation, pH measurement, buffer preparation, and lab safety) as well as performing basic mathematical calculations.

Additional Information

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