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Process Reliability Manager Jobs in Buffalo, NY (NOW HIRING)

Kedrion S.p.A.

Laboratory Manager

Amherst, NY · On-site

KEDPLASMA specializes in the collection and procurement of high-quality plasma that is processed ... Monitor and validate laboratory test results, ensuring accuracy and reliability across all testing ...

STONY MFG

Machine Shop Manager

Elma, NY · On-site

$35 - $45/hr

Ensure all machining processes meet quality standards, tolerances, and customer specifications ... and reliability. Our team thrives on craftsmanship, innovation, and a strong culture of ...

Ecopack USA Inc.

Operations Manager

Tonawanda, NY · On-site

Drive operational excellence through process improvement, automation, cost reduction, and ... reliability and uptime. * Collaborate with Sales, Finance, HR, and other departments to support ...

H5 Data Centers

Data Center Project Manager

Lockport, NY · On-site

$125K - $130K/yr

... processes. * Offers recommendations for increased reliability of all systems. Qualifications ... Five years project management experience. * Reading and understanding * blueprints * schematics ...

H5 Data Centers

Data Center Project Manager

Buffalo, NY · On-site

$125K - $130K/yr

... processes. * Offers recommendations for increased reliability of all systems. Qualifications ... Five years project management experience. * Reading and understanding * blueprints * schematics ...

Unifrax I LLC

Production Manager

Tonawanda, NY · On-site

$120.90 - $138.91/hr

... reliability, and sustainability. * Leadership and Team Development: lead, coach, and develop Shift ... initiatives, process enhancements, and waste reduction opportunities; partner with ...

Alkegen

Production Manager

Buffalo, NY · On-site

Participate in continuous improvement efforts to drive operational efficiency, reliability, and ... Identify and implement cost-saving initiatives, process enhancements, and waste reduction ...

Evonik Industries

Plant Manager

Tonawanda, NY · On-site

$138K - $230K/yr

Ensure resources to maintain product quality, plant reliability, and sustained capacity * Oversee ... Experience in process engineering * Proven supervisory/people leadership experience * 8-10 years of ...

Evonik

Plant Manager

Tonawanda, NY · On-site

$138K - $230K/yr

Ensure resources to maintain product quality, plant reliability, and sustained capacity * Oversee ... Experience in process engineering * Proven supervisory/people leadership experience * 8-10 years of ...

Dupont

Maintenance Engineer

Buffalo, NY · On-site

Develop, review, and improve maintenance procedures, job plans, and checklists; initiate Management ... Familiarity with Global Maintenance Work Processes (GMWP) and reliability frameworks * Strong ...

Alkegen

Production Manager

Buffalo, NY · On-site

Participate in continuous improvement efforts to drive operational efficiency, reliability, and ... Identify and implement cost-saving initiatives, process enhancements, and waste reduction ...

Evonik group

Plant Manager

Tonawanda, NY · On-site

$138.20 - $230.30/hr

Ensure resources to maintain product quality, plant reliability, and sustained capacity* Oversee ... Experience in process engineering* Proven supervisory/people leadership experience* 8-10 years of ...

Newbury Franklin LLC

Operations Manager

Buffalo, NY · On-site

$90K - $110K/yr

... Drive process standardization, waste reduction, and cost optimization across all operational ... evaluate vendor performance to ensure reliability and cost effectiveness. • Oversee ...

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All JobsProcess Reliability JobsProcess Reliability Manager JobsProcess Reliability Manager Jobs in Buffalo, NY

Process Reliability Manager information

See Buffalo, NY salary details

$60.1K

$113.8K

$163.2K

How much do process reliability manager jobs pay per year?

As of Aug 22, 2026, the average yearly pay for process reliability manager in Buffalo, NY is $113,806.00, according to ZipRecruiter salary data. Most workers in this role earn between $91,500.00 and $135,600.00 per year, depending on experience, location, and employer.

What is a process reliability manager?

A Process Reliability Manager is a professional responsible for ensuring that manufacturing or production processes operate efficiently, consistently, and with minimal downtime. They analyze process data, identify areas for improvement, and implement strategies to enhance equipment reliability and overall process performance. By collaborating with maintenance, engineering, and operations teams, they help reduce failures, optimize productivity, and maintain quality standards. Their work is crucial for minimizing costs and ensuring that production targets are met safely and reliably.

What are the key skills and qualifications needed to thrive as a process reliability manager, and why are they important?

To thrive as a Process Reliability Manager, you need a strong background in engineering, process optimization, and reliability analysis, often supported by a degree in engineering and experience in manufacturing or industrial settings. Familiarity with reliability-centered maintenance (RCM), root cause analysis tools, and data analysis software such as SAP or Maximo is typically required. Exceptional problem-solving, leadership, and communication skills help drive cross-functional teams and foster a culture of continuous improvement. These skills are crucial to ensure equipment reliability, minimize downtime, and optimize operational efficiency within complex production environments.

How does a process reliability manager typically collaborate with maintenance and production teams to achieve operational goals?

A Process Reliability Manager works closely with both maintenance and production teams to identify areas of improvement in equipment reliability and process efficiency. This often involves facilitating cross-functional meetings, analyzing downtime data, and implementing preventive maintenance strategies. Clear communication and teamwork are key, as the role requires aligning the objectives of different departments to minimize unplanned outages and optimize production output. By fostering a proactive culture and sharing best practices, the Process Reliability Manager helps ensure the plant operates smoothly and efficiently.

What is the difference between Process Reliability Manager vs Maintenance Engineer?

AspectProcess Reliability ManagerMaintenance Engineer
CertificationsReliability certifications, Six Sigma, PMPMechanical/Electrical certifications, HVAC, PLC certifications
Work EnvironmentManufacturing plants, industrial facilitiesFactories, equipment maintenance sites
Industry UsageFocus on reliability, uptime, and process optimizationFocus on equipment repair, preventive maintenance

The Process Reliability Manager primarily focuses on improving equipment reliability and process efficiency through data analysis and strategic planning. In contrast, Maintenance Engineers handle the hands-on repair and maintenance of machinery. Both roles are essential in manufacturing, but the Process Reliability Manager emphasizes proactive reliability strategies, while Maintenance Engineers focus on reactive and preventive maintenance tasks.

What cities near Buffalo, NY are hiring for Process Reliability Manager jobs?

Cities near Buffalo, NY with the most Process Reliability Manager job openings:

Process Reliability Manager jobs near you
Infographic showing various Process Reliability Manager job openings in Buffalo, NY as of July 2026, with employment types broken down into 83% Full Time, 15% Part Time, 1% Temporary, and 1% Contract. Highlights an 86% Physical, 1% Hybrid, and 13% Remote job distribution, with an average salary of $113,806 per year, or $54.7 per hour.

Laboratory Manager

Kedrion S.p.A.

Amherst, NY • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 21 days ago

Job description

Posting Start Date: 6/30/26
State/Province: New York
Job Location: Amherst
Place of Employment:
Contract Duration: Permanent
Hiring Pay Range Min: 96,280
Hiring Pay Range Max: 144,420
Laboratory Manager
KEDPLASMA is a subsidiary of Kedrion Biopharma Inc. KEDPLASMA specializes in the collection and procurement of high-quality plasma that is processed into plasma-based therapies. Kedrion Biopharma Inc. is an international company specializing in the collection and fractionation of blood plasma to produce and distribute plasma-derived therapeutic products. Our therapies help treat and prevent serious diseases, including Hemophilia, Primary Immune System Deficiencies, and Rh-Sensitization.
Job Summary
Lead the science behind life-saving therapies as a Laboratory Manager. In this role, you will oversee daily laboratory operations supporting specialty plasma programs, ensuring accurate testing, regulatory compliance, and high-quality outcomes. You will play a critical role in maintaining laboratory performance, advancing testing capabilities, and delivering results that meet strict industry standards while supporting organizational goals and customer requirements.
What you'll do
  • Oversee daily laboratory operations, including testing specialty plasma samples, ensuring accuracy, efficiency, and compliance with regulatory standards such as FDA cGMP, CLIA, and OSHA requirements
  • Create, update, and enforce Standard Operating Procedures (SOPs) aligned with the Quality Management System (QMS) to ensure consistent execution of laboratory processes
  • Coordinate laboratory testing activities including sample processing, test execution, instrument calibration, maintenance, troubleshooting, and quality control/assurance
  • Monitor and validate laboratory test results, ensuring accuracy and reliability across all testing activities
  • Manage laboratory inventory, ordering supplies, reagents, and consumables required for uninterrupted operations
  • Calculate and evaluate quality control metrics, including standard deviations and calibration standards, to ensure proper test performance
  • Oversee outsourced testing processes, including coordinating sample logistics and communication with external laboratories
  • Maintain accurate data entry, donor records, and testing documentation, ensuring proper tracking and compliance with program requirements
  • Manage specialty program inventory and collaborate with Supply Chain, Quality, and operational teams to ensure appropriate stock levels and customer fulfillment
  • Configure and prepare customer sample pools to meet volume and potency specifications, and coordinate shipment execution
  • Implement and validate new testing methods, instruments, and procedures to meet evolving customer and regulatory requirements
  • Schedule and maintain laboratory equipment, including preventative maintenance, calibration, and validation documentation
  • Support internal and external audits by providing required documentation and driving corrective actions where needed
  • Communicate effectively with vendors, technical support teams, and customer representatives to resolve issues and maintain service standards
  • Oversee licensing requirements and support renewal processes to maintain operational compliance
  • Lead, develop, and manage laboratory staff, including hiring, training, coaching, performance management, and workload distribution
  • Foster a positive, collaborative, and performance-driven work environment that supports employee engagement and retention

Qualifications and need-to-know
  • Bachelor's degree in Life Sciences or a related field required
  • ASCP certification or equivalent national certification required
  • Licensed Clinical Laboratory Supervisor across relevant specialties preferred
  • 5-10 years of experience in a hospital laboratory, plasma, or blood collection environment preferred
  • Knowledge of laboratory testing protocols and viral marker testing preferred
  • Strong understanding of regulatory requirements including FDA cGMP, CLIA, and OSHA standards
  • Demonstrated experience managing laboratory operations, including quality control, equipment maintenance, and testing procedures
  • Proven leadership experience with the ability to manage, coach, and develop team members
  • Experience with laboratory data management and documentation processes
  • Ability to implement new procedures, validate methods, and adapt to evolving operational requirements

Employment eligibility verification will be required at the time of hire. This position does not offer visa sponsorship now or in the future.
Kedrion Biopharma Inc. is committed to providing equal employment opportunities to all employees and applicants. We prohibit discrimination and harassment based on race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws. This policy applies to all employment terms, including recruitment, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.
Salary ranges are determined based on relevant experience, education, and certifications.
If you require assistance with your employment application or need reasonable accommodations to perform job duties, please contact our Talent Acquisition team at kedtalent@kedrion.com.
Employee Benefits: At Kedrion Biopharma Inc., we believe in taking care of our people. Our benefits package is designed to support your health, happiness, and future, including:
  • Health & Wellness - Full medical, dental, and vision coverage
  • Financial Security - Life insurance, AD&D, and retirement savings plans
  • Work-Life Balance - Paid time off, sick leave, and paid holidays
  • Career Growth - Training programs and development opportunities
  • Extra Perks - Employee discounts, wellness initiatives, and more!

For specific inquiries please reach out to us
Kedrion Biopharma Inc. participates in E-Verify and provides the federal government with Form I-9 information to confirm employment authorization. For more information, please contact the Department of Homeland Security.

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