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Process Engineer Jobs in St Louis, MO (NOW HIRING)

Learn and apply engineering fundamentals to support manufacturing process improvements related to safety, quality, delivery, cost, and waste reduction. * Support work order improvement activities and ...

New

Learn and apply engineering fundamentals to support manufacturing process improvements related to safety, quality, delivery, cost, and waste reduction. * Support work order improvement activities and ...

New

Senior Process Engineer (REQ865)

Saint Louis, MO · Remote

$106K - $137K/yr

Senior Process Engineer Maryland Heights, MO Spartech offers a competitive salary, incentives, and benefit programs! Spartech, LLC, headquartered in Maryland Heights, Missouri, has over a dozen ...

Senior Process Engineer (REQ865)

Saint Louis, MO · On-site +1

$98K - $127K/yr

Senior Process Engineer Maryland Heights, MO Spartech offers a competitive salary, incentives, and benefit programs! Spartech, LLC, headquartered in Maryland Heights, Missouri, has over a dozen ...

Process Lead Engineer

Saint Louis, MO · On-site

$96K - $125K/yr

The Process Engineer works closely with clients, process architects, utilities engineers, mechanical engineers, and construction teams to translate manufacturing processes into clear, coordinated ...

Showing results 21-40

Process Engineer information

See St Louis, MO salary details

$48.1K

$89.5K

$138.5K

How much do process engineer jobs pay per year?

As of Sep 11, 2026, the average yearly pay for process engineer in St. Louis, MO is $89,462.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,400.00 and $100,100.00 per year, depending on experience, location, and employer.

What is a process engineer?

Process Engineers are professionals who design, implement, and optimize industrial processes to improve efficiency, quality, and safety in manufacturing or production environments. They analyze workflows, troubleshoot process issues, and develop solutions to enhance productivity and reduce costs. Process Engineers often work in industries such as chemicals, pharmaceuticals, food and beverage, and energy, ensuring processes are compliant with environmental and safety regulations. Their work is vital for maintaining smooth operations and achieving organizational goals.

What are the key skills and qualifications needed to thrive as a process engineer, and why are they important?

To thrive as a Process Engineer, you need a solid background in chemical, mechanical, or industrial engineering, often supported by a relevant bachelor's degree and understanding of process optimization principles. Familiarity with process simulation software (such as Aspen Plus or AutoCAD), Six Sigma methodologies, and quality management systems is typically required. Strong analytical thinking, problem-solving abilities, and effective communication skills set candidates apart in this role. These skills and qualifications are essential to improve efficiency, ensure safety, and drive continuous improvement in industrial and manufacturing processes.

What are some common challenges process engineers face when implementing process improvements, and how can they overcome them?

Process Engineers often encounter challenges such as resistance to change from team members, integrating new technologies with existing systems, and ensuring process changes meet regulatory standards. Overcoming these obstacles typically involves clear communication, involving stakeholders early in the process, thorough documentation, and piloting changes before full-scale implementation. Building strong cross-functional relationships and continuously gathering feedback also help ensure that improvements are effective and sustainable.

What is the difference between Process Engineer vs Manufacturing Engineer?

AspectProcess EngineerManufacturing Engineer
CredentialsBachelor's in Engineering, certifications like Six SigmaBachelor's in Engineering, certifications like Lean Manufacturing
Work EnvironmentDesigning and optimizing processes, R&D settingsOverseeing production lines, factory floors
Industry UsageManufacturing, chemical, aerospaceAutomotive, electronics, consumer goods

Process Engineers focus on designing and improving manufacturing processes, often working in R&D or engineering departments. Manufacturing Engineers concentrate on implementing and managing production on the factory floor. Both roles require similar technical skills and certifications but differ mainly in their scope and work environment.

What jobs can a process engineer do?

A process engineer designs, develops, and optimizes manufacturing processes to improve efficiency, quality, and safety. They work in industries such as chemical, pharmaceutical, food, and automotive, often using tools like process simulation software and requiring knowledge of quality standards and safety regulations.

What are the most commonly searched types of Process Engineer jobs in St. Louis, MO?

The most popular types of Process Engineer jobs in St. Louis, MO are:

What job categories do people searching Process Engineer jobs in St. Louis, MO look for?

The top searched job categories for Process Engineer jobs in St. Louis, MO are:

What cities near St. Louis, MO are hiring for Process Engineer jobs?

Cities near St. Louis, MO with the most Process Engineer job openings:

Infographic showing various Process Engineer job openings in St. Louis, MO as of September 2026, with employment types broken down into 3% Internship, 91% Full Time, 3% Part Time, and 3% Contract. Highlights an 97% In-person, and 3% Remote job distribution, with an average salary of $89,462 per year, or $43 per hour.

Process Engineer - Life Sciences

Saint Louis, MO

Clayco (LJC)
Construction • 1 - 5K employees

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted yesterday


Clayco rating

8.6

Company rating: 8.6 out of 10

Based on 6 frontline employees who took The Breakroom Quiz


Job description

About Us

Clayco is a full-service, turnkey real estate development, master planning, architecture, engineering, and construction firm that safely delivers clients across North America the highest quality solutions on time, on budget, and above and beyond expectations. With $8.1 billion in revenue for 2025, Clayco specializes in the "art and science of building," providing fast track, efficient solutions for mission critical, industrial, life sciences, power & energy, aviation, commercial, institutional, residential and sports & entertainment related building projects.

About LJC

LJC Design & Engineering is a full-service architecture, engineering, and design firm committed to enhancing the quality of the human experience through integrated design. We are a team of high-energy professionals who share a passion for design, a collaborative approach, and a casual culture. We solve challenges by leveraging the collective expertise and ingenuity of the best and brightest minds across development, design, and construction.

The Role We Want You For

LJC is seeking an experienced Process Engineer to support the planning, design, and delivery of life sciences manufacturing facilities across a range of therapeutic and production modalities. This role focuses on defining process requirements, equipment needs, and operational workflows that inform facility planning and engineering design for regulated manufacturing environments.

The Process Engineer works closely with clients, process architects, utilities engineers, mechanical engineers, and construction teams to translate manufacturing processes into clear, coordinated design solutions. While experience across multiple modalities is valued, candidates with deep expertise in a specific modality are strongly encouraged to apply.

The Specifics of the Role

  • Lead or support process definition and design efforts for life sciences manufacturing facilities from early planning through construction support.
  • Define process flows, unit operations, equipment requirements, and space needs to support regulated manufacturing operations.
  • Develop process narratives, block flow diagrams, and equipment layouts that inform architectural and engineering design.
  • Collaborate with clients to understand manufacturing objectives, capacity requirements, product mix, and operational constraints.
  • Work closely with process architects and project teams to translate process requirements into compliant, efficient, and flexible facility layouts.
  • Coordinate with critical utilities, mechanical, electrical, automation, and architectural teams to align process needs with supporting systems and infrastructure.
  • Support front-end project efforts by contributing to proposals, technical narratives, and early planning concepts.
  • Participate in client meetings, technical workshops, and planning sessions related to process definition, capacity planning, and operational strategy.
  • Support compliance with applicable regulatory requirements, including GMP/GxP expectations and relevant industry guidelines.
  • Review process-related design deliverables to ensure alignment with defined process requirements and overall project objectives.
  • Participate in multidisciplinary coordination reviews to resolve process-related design challenges.
  • Stay current with emerging technologies, manufacturing platforms, and best practices across life sciences modalities.

Requirements

  • Bachelor’s degree in Chemical Engineering, Biochemical Engineering, Mechanical Engineering, or a related technical field.
  • 10+ years of experience in life sciences manufacturing process engineering within pharmaceutical, biotechnology, or advanced therapy environments.
  • Demonstrated experience supporting at least one major life sciences manufacturing modality, such as:
  • Monoclonal antibodies (mAbs)
  • Fill–finish (aseptic or non-aseptic)
  • Advanced therapy medicinal products (ATMPs), including cell and gene therapies
  • mRNA
  • Vaccines
  • Active pharmaceutical ingredients (API)
  • Oral solid dosage (OSD)
  • Exposure to additional modalities, platforms, or production technologies is preferred but not required.
  • Strong understanding of regulated manufacturing processes, unit operations, and equipment typical of life sciences facilities.
  • Experience translating process requirements into facility design inputs, equipment layouts, and engineering criteria.
  • Familiarity with GMP/GxP environments and regulatory expectations.
  • Experience working in a design-build or fast-track project delivery environment preferred.
  • Strong communication skills, with the ability to engage in client-facing technical discussions and multidisciplinary coordination.
  • Ability to collaborate effectively across engineering, architectural, and construction teams.
  • Professional Engineer (PE) licensure preferred but not required.

Some Things You Should Know

  • Our clients and projects are nationwide
  • No other builder can offer the collaborative design-build approach that Clayco does.
  • We work on creative, complex, award-winning, high-profile jobs.
  • The pace is fast!

Why Clayco and LJC?

  • 2025 Best Places to Work – St. Louis Business Journal, Los Angeles Business Journal, and Phoenix Business Journal.
  • 2025 ENR Top 400 – Top Data Center Contractor (Top 3).
  • 2025 ENR Top 100 Design-Build Firms – Design-Build Contractor (Top 5).
  • 2025 ENR Top 100 Green Contractors – Green Contractor (Top 3).

Benefits

  • Discretionary Annual Bonus: Subject to company and individual performance.
  • Comprehensive Benefits Package Including: Medical, dental and vision plans, 401k, generous PTO and paid company holidays, employee assistance program, flexible spending accounts, life insurance, disability coverage, learning & development programs and more!

Compensation

  • The salary range for this position considers a wide range of factors in making compensation decisions including but not limited to: Education, qualifications, skills, training, experience, certifications, internal equity, and location. Compensation decisions are dependent on the facts and circumstances of each case.

What Clayco employees say

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