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Principal Ai Jobs (NOW HIRING)

Sanford Health

Principal AI Architect

Sioux Falls, SD · On-site

$53/hr

Summary The Principal AI Architect is responsible for designing, governing, and implementing enterprise AI/ML solutions that improve clinical outcomes, operational efficiency, workforce productivity ...

Venturegloballng

Principal, AI Engineer

Arlington, VA · On-site

Principal, AI Engineer Located: Arlington Summary The Principal AI Engineer is the senior-most individual contributor and technical authority within Venture Global's AI Engineering function. This ...

Stanley Martin Homes

Principal AI Engineer

Reston, VA · On-site

The Principal AI Engineer will work directly with teams across Finance, Team and Culture, Operations, Sales, Purchasing, and Land to understand how work gets done, identify where agentic AI can ...

Sanford Health

Principal AI Architect

Sioux Falls, SD · On-site

$53/hr

Summary The Principal AI Architect is responsible for designing, governing, and implementing enterprise AI/ML solutions that improve clinical outcomes, operational efficiency, workforce productivity ...

Sanford Health

Principal AI Architect

$53/hr

Summary The Principal AI Architect is responsible for designing, governing, and implementing enterprise AI/ML solutions that improve clinical outcomes, operational efficiency, workforce productivity ...

Korn Ferry Executive Search

Principal AI Architect

MN · Remote

Principal AI Architect Compensation Range: $200,000-220,000 + Bonus + Benefits Location: Remote, USA Type: Full-time Industry: Payments Technology / B2B About the Company Our client is building a ...

Brightli

Principal AI Engineer

Springfield, MO · On-site

Principal AI Engineer Location: Springfield, Missouri Department: Information Technology Employment Type: Full-time Job Summary: Join a compassionate, collaborative team making a measurable ...

Brightli

Principal AI Engineer

Springfield, MO · On-site

Principal AI Engineer Location: Springfield, Missouri Department: Information Technology Employment Type: Full-time Job Summary: Join a compassionate, collaborative team making a measurable ...

Good Samaritan Society

Principal AI Architect

Iowa, LA · On-site

$250/hr

Job Summary The Principal AI Architect is responsible for designing, governing, and implementing enterprise AI/ML solutions that improve clinical outcomes, operational efficiency, workforce ...

Brightli

Principal AI Engineer

Springfield, MO · On-site

Principal AI Engineer Location: Springfield, Missouri Department: Information Technology Employment Type: Full-time Job Summary: Join a compassionate, collaborative team making a measurable ...

Hop

Principal AI Architect

San Francisco, CA · On-site

They are seeking a Principal AI Architect to define the architectural vision for next-generation AI systems and evaluate breakthrough AI capabilities. Responsibilities : • Define and own the ...

The Fannie Mae

Principal, AI Solutions

Virginia, MN · On-site

## Principal, AI SolutionsApplyremote type: Flexlocations: Reston, VA: Washington, DC: Plano, TXtime type: Full timeposted on: Posted 3 Days Agojob requisition id: JR2676Playing an essential role in the ...

Elevance Health

Principal AI Engineer

Atlanta, GA · Hybrid

Principal AI Engineer Principal AI Engineer Location: This role requires associates to be in-office 1 - 2 days per week, fostering collaboration and connectivity, while providing flexibility to ...

Surescripts

Principal AI Engineer

Charleston, WV · Hybrid

The Principal AI Engineer is the most senior individual contributor and technical lead for Surescripts' AI solutions. The role owns the how, the execution, and the by-when for AI initiatives across ...

Columbia University

We have an immediate opening for a Principal AI Engineer to help lead this work. The ideal candidate is a talented and self-motivated individual with a strong machine learning background, deep ...

Surescripts

Job Summary The Principal AI Engineer is the most senior individual contributor and technical lead for Surescripts' AI solutions. The role owns the how, the execution, and the by-when for AI ...

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As of Sep 11, 2026, the average yearly pay for principal ai in the United States is $109,393.00, according to ZipRecruiter salary data. Most workers in this role earn between $85,000.00 and $125,000.00 per year, depending on experience, location, and employer.

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Principal AI Architect

Sioux Falls, SD • On-site

Sanford Health
Health Care and Social Assistance • 10K+ employees
Learn more about Sanford Healthexternal

$53/hr

Full-time

This job post has expired 1 day ago. Applications are no longer accepted.

Sanford Health rating

6.7

Company rating: 6.7 out of 10

Based on 561 frontline employees who took The Breakroom Quiz

Job description

Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America's heartland.
Work Shift:
8 Hours - Day Shifts (United States of America)
Scheduled Weekly Hours:
40
Compensation:
Salary Range: $53.00 - $87.50Pay starts at $53 and increases according to yeas of applicable experience.
Union Position:
No
Department Details
Don't miss this opportunity to join talented team of architects as we build new enterprise AI products and functions. Experience a great work environment and enjoy the satisfaction of helping deliver our healthcare mission.
Summary
The Principal AI Architect is responsible for designing, governing, and implementing enterprise AI/ML solutions that improve clinical outcomes, operational efficiency, workforce productivity, and business performance across Sanford. Serves as a technical leader, partnering with business stakeholders, clinical leaders, data teams, and technology teams to translate business challenges into scalable, secure, and compliant AI-enabled solutions.
The Principal AI Architect defines architecture standards, evaluates emerging AI technologies, and ensures solutions align with organizational goals, healthcare regulations, security requirements, and responsible AI principles. Combines expertise in AI, cloud architecture, data platforms, healthcare interoperability, and enterprise integration.
Job Description
The Principal AI Architect designs and implements enterprise AI architectures supporting: Generative AI, Machine Learning, Conversational AI, Intelligent Automation, Predictive Analytics, and Clinical Decision Support. Develops architecture patterns, standards, and reference designs for AI solutions. Creates scalable, resilient, and secure AI platforms across cloud and hybrid environments. Defines integration approaches connecting AI systems with enterprise applications and data platforms.
Designs AI solutions that leverage healthcare data while maintaining privacy and security requirements. Architects integrations with healthcare and business systems such as EHR, ERP, HR, and collaboration platforms. Supports implementation of healthcare interoperability standards including HL7, FHIR, CDA, DICOM, and X12. Collaborates with data architects and engineers to establish AI-ready data pipelines and governance frameworks.
Ensures AI solutions comply with HIPAA, HITECH, organizational security standards, and healthcare regulatory requirements. Establishes controls for model governance, monitoring, auditability, and responsible AI practices. Conducts architecture reviews and risk assessments for AI initiatives. Partners with cybersecurity, compliance, and privacy teams to mitigate AI-related risks.
Evaluates emerging AI technologies, vendors, platforms, and frameworks. Develops recommendations regarding build-versus-buy decisions. Leads proof-of-concept and pilot initiatives for new AI capabilities. Stays current with healthcare AI trends and industry best practices.
Partners with clinical, operational, and business leaders to identify AI opportunities. Translates complex technical concepts into business-friendly recommendations. Provides architectural guidance to engineers, developers, and data scientists. Participates in architecture governance and strategic planning activities. Contributes to AI education, adoption, and change management efforts across the organization.
Qualifications
Bachelor's degree in Computer Science, Information Technology, Engineering or a related technical field required. Master's degree is preferred.
7 years of experience in solution architecture, application architecture, data architecture, or software engineering. 3 years of experience designing AI, machine learning, analytics, or automation solutions. Experience with cloud platforms such as Microsoft Azure, AWS, or Google Cloud. Experience designing enterprise integrations using APIs, event-driven architecture, or middleware platforms. Experience working with complex enterprise systems and data environments.
AI and Cloud architecture certifications preferred.
Sanford is an EEO/AA Employer M/F/Disability/Vet.
If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-949-5678 or send an email to talent@sanfordhealth.org.

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About Sanford Health

Sourced by ZipRecruiter

Sanford Health is one of the largest and fastest-growing not-for-profit health systems in the United States. We're proud to offer many development and advancement opportunities to our nearly 50,000 members of the Sanford Family who are dedicated to the work of health and healing across our broad footprint.

Industry

Health care and social assistance and hospitals

Company size

10,000+ Employees

Headquarters location

Sioux Falls, SD, US

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