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Postdoctoral Position In Nucleic Acid Chemistry Jobs

Rutgers University

Post Doctoral Associate

Piscataway, NJ · On-site

$63K/yr

... postdoc position will be given to candidates with proven expertise in nucleic acids chemistry ... Candidates with expertise in medicinal chemistry, drug discovery, nucleic acid chemistry, and/or ...

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Postdoctoral Position In Nucleic Acid Chemistry information

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$59K

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How much do postdoctoral position in nucleic acid chemistry jobs pay per year?

As of Jun 6, 2026, the average yearly pay for postdoctoral position in nucleic acid chemistry in the United States is $59,022.00, according to ZipRecruiter salary data. Most workers in this role earn between $49,000.00 and $66,500.00 per year, depending on experience, location, and employer.

What is a Postdoctoral Position in Nucleic Acid Chemistry?

A Postdoctoral Position in Nucleic Acid Chemistry is a temporary research job, typically taken after earning a PhD, that focuses on studying the structure, function, and modification of nucleic acids like DNA and RNA. Researchers in these roles work in academic, government, or industry labs to develop new techniques, understand nucleic acid interactions, or create novel molecules for applications in medicine and biotechnology. These positions provide valuable experience, help build a publication record, and often serve as a stepping stone toward independent research careers or faculty positions.

What are the typical research collaborations and team structures for a postdoctoral position in nucleic acid chemistry?

In a postdoctoral position focusing on nucleic acid chemistry, you can expect to work closely with interdisciplinary teams that often include chemists, molecular biologists, and biochemists. Collaboration with other labs, both within and outside your institution, is common—particularly when projects require specialized expertise or advanced instrumentation. Regular lab meetings, joint research projects, and co-authored publications are typical, fostering a collaborative environment that supports both independent and team-based work. These interactions not only enhance the quality of research but also provide valuable networking and learning opportunities.

What are the key skills and qualifications needed to thrive as a Postdoctoral Researcher in Nucleic Acid Chemistry, and why are they important?

To thrive as a Postdoctoral Researcher in Nucleic Acid Chemistry, you need a strong background in organic and nucleic acid chemistry, with a Ph.D. in chemistry, biochemistry, or a related field. Familiarity with techniques such as oligonucleotide synthesis, HPLC, NMR, mass spectrometry, and molecular biology tools is typically required. Critical thinking, problem-solving, and effective collaboration are key soft skills that enhance research productivity and innovation. These skills are crucial for advancing scientific discoveries, publishing impactful research, and contributing effectively to multidisciplinary teams.

Director, Nucleic Acid Delivery

Lila Sciences

Cambridge, MA

Other

Posted 26 days ago

Job description

Your Impact at LILA

The Director of Nucleic Acid Delivery will lead the discovery and engineering of next-generation delivery systems for nucleic acid cargo. This role will drive the design of targeted lipid nanoparticles (tLNPs) and other biological delivery modalities to enable precise delivery of nucleic acids across diverse tissues and cell types.
 
Leveraging the Lila Sciences AI platform and AI Science Factory, this leader will guide an interdisciplinary team of scientists in integrating AI-driven hypothesis generation, robotics-enabled experimentation, and biological insight to accelerate discovery of transformative delivery technologies. The role will focus on the biological targeting and functional delivery, while collaborating closely with formulation scientists responsible for lipid composition and formulation optimization.
 
This position is ideal for a creative scientific leader who believes that AI, automation, and integrated biological systems thinking will fundamentally reshape therapeutic discovery. The successful candidate will bring deep expertise in nucleic acid delivery and a passion for building collaborative teams.

What You'll Be Building

  • Lead and build a high-performing team of senior scientists, scientists, and research associates focused on nucleic acid delivery technology development.
  • Drive the discovery and engineering of targeted lipid nanoparticle systems for delivery of nucleic acid therapeutics.
  • Design and evaluate targeting ligands, conjugation strategies, and nanoparticle architectures that enable tissue- and cell-specific delivery.
  • Develop and implement innovative biological assays and screening platforms to evaluate delivery efficiency, biodistribution, cellular uptake, and functional nucleic acid expression or editing.
  • Leverage the Lila AI platform and AI Science Factory to accelerate design-build-test-learn cycles through AI-driven experimental design and robotics-enabled experimentation.
  • Collaborate closely with formulation scientists to integrate biological targeting strategies with lipid chemistry and nanoparticle formulation optimization.
  • Explore and evaluate next-generation delivery modalities that extend beyond traditional LNPs.
  • Establish strategic scientific direction for nucleic acid delivery research and ensure alignment with company-wide therapeutic goals.
  • Foster a culture of innovation, collaboration, and scientific rigor, mentoring team members and developing future leaders in the field.

What You'll Need to Succeed

  • PhD in molecular biology, bioengineering, chemical biology, biomedical engineering, pharmacology, or a related discipline with 8-10+ years of relevant industry or academic experience, or a BS/MS with 12-15+ years of experience in nucleic acid delivery or genetic medicine.
  • Demonstrated expertise in lipid nanoparticle technologies, nucleic acid delivery systems, or related genetic medicine platforms.
  • Strong track record of scientific leadership and mentorship, including managing multidisciplinary research teams.
  • Experience designing and executing in vitro and in vivo assays to measure delivery efficiency, biodistribution, and functional activity of nucleic acid therapeutics.
  • Deep understanding of the biological mechanisms underlying delivery, including cellular uptake, endosomal escape, tissue targeting, and intracellular trafficking.
  • Experience collaborating across disciplines including formulation chemistry, molecular biology, protein engineering, and pharmacology.
  • Track record of impactful scientific contributions demonstrated through publications, patents, or therapeutic development programs.
  • Excellent communication and strategic thinking skills with the ability to translate complex scientific ideas into actionable research programs.

Bonus Points For

  • Direct experience developing targeted LNP systems or ligand-directed nanoparticle delivery technologies.
  • Expertise in RNA therapeutics, gene editing systems (e.g., CRISPR/Cas), siRNA, mRNA, or DNA therapeutics.
  • Experience integrating AI-driven discovery tools, high-throughput experimentation, or automated laboratory platforms into biological research.
  • Experience working in highly collaborative environments spanning biology, chemistry, computational science, and engineering.
  • Demonstrated ability to translate early discovery concepts into therapeutically relevant delivery platforms.
  • Entrepreneurial mindset with a passion for pushing the boundaries of AI-enabled scientific discovery.

Apply