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Postdoc Single Cell Rna Sequencing Analysis Jobs in Ohio

Our research focuses on m6A RNA methylation and its roles in developmental cell fate decisions ... and single-cell/multi-omics approaches, we investigate the molecular regulation of heart ...

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Postdoc Single Cell Rna Sequencing Analysis information

What is the difference between Postdoc Single Cell Rna Sequencing Analysis vs Postdoc Bioinformatics?

AspectPostdoc Single Cell Rna Sequencing AnalysisPostdoc Bioinformatics
Required CredentialsPhD in Biology, Genetics, or related field; experience in sequencing data analysisPhD in Computer Science, Bioinformatics, or related field; programming skills essential
Work EnvironmentResearch labs focusing on genomics and cell biologyResearch institutions, biotech companies, or academic labs with computational focus
Employer & Industry UsageBiotech, academic research, pharmaceutical companiesBiotech, healthcare, academic research, industry R&D

Postdoc Single Cell Rna Sequencing Analysis specialists focus on analyzing single-cell transcriptomics data, often requiring biological expertise and lab experience. In contrast, Postdoc Bioinformatics roles emphasize computational skills and software development to interpret large datasets across various biological contexts. Both roles are vital in genomics research but differ in their primary focus and skill set.

What are the key skills and qualifications needed to thrive as a postdoc in single cell RNA sequencing analysis, and why are they important?

To thrive as a Postdoc in Single Cell RNA Sequencing Analysis, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by a PhD in a relevant field. Proficiency with computational tools such as R, Python, and specialized single-cell analysis platforms (e.g., Seurat, Scanpy), as well as experience with data visualization and next-generation sequencing, is essential. Strong problem-solving abilities, effective communication, and collaboration skills help distinguish top candidates in interdisciplinary research environments. These skills enable accurate data interpretation, drive innovation, and support impactful scientific discoveries in complex biological systems.

What are some common challenges faced by postdocs working in single cell RNA sequencing analysis, and how can they be addressed?

Postdocs in single cell RNA sequencing analysis often encounter challenges such as managing large and complex datasets, integrating multi-omic data, and staying current with rapidly evolving bioinformatics tools. Collaborating closely with wet lab scientists and computational biologists is essential to interpret results accurately and to troubleshoot technical issues. Building strong programming and statistical skills, as well as actively participating in lab meetings and seminars, can help address these challenges and contribute to both personal growth and successful project outcomes.

What does a postdoc in single cell RNA sequencing analysis do?

A Postdoc in Single Cell RNA Sequencing (scRNA-seq) Analysis specializes in analyzing gene expression data from individual cells. Their main responsibilities include processing raw sequencing data, performing quality control, identifying cell types or states, and interpreting biological insights from the data. They often develop or apply computational methods to handle large datasets, collaborate with experimental biologists, and present findings through publications or conferences. The ultimate goal is to understand cellular heterogeneity and uncover new biological mechanisms at the single-cell level.

Postdoctoral Research Fellow - Bioinformatics Analyst (Lim)

Cincinnati Children's

Cincinnati, OH • On-site

$47K - $63K/yr

Full-time

Posted 9 days ago


Cincinnati Children's Hospital Medical Center rating

7.3

Company rating: 7.3 out of 10

Based on 150 frontline employees who took The Breakroom Quiz

386th of 1,055 rated hospitals


Job description

Primary Location
Exploration Avenue
Department
Biomedical Informatics
Shift
Day (United States of America)
Schedule
Full time
Weekly Hours
40
FTE
1
Employee Status
Regular
The Computational Regulatory Genomics Laboratory (https://computbio.org) at the Cincinnati Children's Hospital Medical Center (CCHMC) is seeking a highly motivated Postdoctoral Research Fellow. The primary research focus of the lab is to understand the fundamental mechanisms of gene transcriptional regulation across various biological contexts, including developmental biology, cancer biology, and metabolism. We are specifically interested in enhancer regulation and systems-level understanding of enhancer architectures and functions across diverse biological contexts. We integrate multi-omics data, including ChIP-seq, ChIP-exo, CUT&RUN, GRO-seq, csRNA-seq, RNA-seq, ATAC-seq, Hi-C, and single-cell technologies, to delineate heterogeneous architectures of transcription factor binding events and chromatin landscapes at high resolution. The lab collaborates with multiple experimental laboratories specialized in metabolism, cancer, and development. The lab's work has been published in many high-profile journals, including Nature, Cell Metabolism, Molecular Cell, Genes & Development, Circulation, Nature Communications, and the Journal of Clinical Investigation.
JOB RESPONSIBILITIES
  • Perform analysis and experiments - Design, execute, and record analysis and experiments; apply standard scientific protocols to research, and improve current methods and evaluate innovative techniques. Develop and implement human subject research protocols, vertebrate animal research protocols and design experimental procedures and documentation in accordance with the relevant laws and regulations. Prepare, clean and analyze data. Maintain optimal protocol and accuracy by conducting regular quality and reproducibility checks.
  • Communicate results/findings - Draft, write, and edit scientific reports, papers, journal articles, and abstracts. Present information on research and department work to others at department meetings, journal clubs, and seminars. Present results and discuss relevant insights with Faculty and provide useful recommendations and analysis.
  • Innovate and advance departmental capabilities - Independently reproduce, evaluate, research, and improve techniques currently used. Adapt new methods to existing procedures and modify current analysis/experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all analysis and experiments. Develop, set-up, and verify new procedures in the department. Standardize and establish new published procedures; evaluate innovative techniques. Develop new protocols; design formats. Maintain an integral role in the department's meetings, presentations, and publications. Troubleshoot and correct erroneous results or problems with department software/equipment. Maintain and repair software/equipment; monitor proper use by personnel.
  • Financial/Budgeting - Assist in preparing grant applications. Assist in preparing, writing, and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests. Prepare, approve, and initiate check requests; track funding, maintain accurate balance, and resolve any discrepancies.
  • Staff Leadership - May provide day-to-day functional leadership for a team or directly manage a minimal number of support staff. Establishes team goals. Gives input into, and performs employee performance reviews. Oversees and guides work assignments. Serves as the functional expert and provides guidance to the team.
  • Education and Training - May serve as course master and develop new courses at the undergraduate and graduate level, including appropriate plans for evaluating student performance; may deliver lectures as a guest lecturer in courses organized by other faculty. Assist in the training of new employees. Serve as a resource and/or mentor to coworkers. Assist in the development and presentation of department training. Identify training needs and provide necessary coaching.

JOB QUALIFICATIONS
  • Ph.D. in related discipline, MD, or equivalent degree
  • Preferred: PhD in Computer Science, Physics, Biomedical Informatics, Bioinformatics, Epidemiology, Biostatistics or other similar quantitative disciplines
  • Preferred: Experience in a related discipline

About Us
At Cincinnati Children's, we come to work with one goal: to make children's health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children's.
Cincinnati Children's is:
  • Recognized by U.S. News & World Report as a top 10best Children's Hospitals in the nation for more than 15 years
  • Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH) Funding
  • Recognized as one of America's Best Large Employers (2025), America's Best Employers for New Grads (2025)
  • One of the nation's America's Most Innovative Companies as noted by Fortune
  • Consistently certified as great place to work
  • A Leading Disability Employer as noted by the National Organization on Disability
  • Magnet® designated for the fourth consecutive time by the American Nurses Credentialing Center (ANCC)

We Embrace Innovation-Together. We believe in empowering our teams with the tools that help us work smarter and care better. That's why we support the responsible use of artificial intelligence. By encouraging innovation, we're creating space for new ideas, better outcomes, and a stronger future-for all of us.
Comprehensive job description provided upon request.
Cincinnati Children's is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/Veteran/Disability

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About Cincinnati Children's Hospital Medical Center

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Cincinnati Children's Hospital Medical Center, located in Cincinnati, OH, US, is a premier pediatric hospital renowned for its exceptional clinical services, research programs, and medical education. The healthcare institution, founded in 1883, holds a sterling reputation in the industry, with a mission to improve child health and transform delivery of care through fully integrated, globally recognized research, education and innovation. As one of the oldest and most distinguished pediatric hospitals in the United States, Cincinnati Children's continues to offer a broad range of high-quality, compassionate care to children in the community and around the globe. As a testament to its dedication, it has consistently been ranked among the top three US pediatric hospitals by U.S. News & World Report.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Cincinnati, OH, US

Year founded

1883